Activate Now
 
ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

The New Dual Activation Pain Relief Cream

SURVEY RESULTS: Medical Marijuana

Recipe: Mega-Golden Milk

Sweep Away Senile Cells

Vitamin D supplementation shows promise for Hashimoto's thyroiditis

A Paleolithic-type diet may help reduce future risk of diabetes and cardiovascular disease

Large whey protein breakfast may help manage type 2 diabetes

Decreased levels of vitamin D associated with reduced methylation in African American teens

Selenium — What Is it and Where Do I Get It?

Meta-analysis adds evidence to antidepressant effect for omega-3

 
Print Page
Email Article

Neuroendocrine and immune network re-modeling in chronic fatigue syndrome: An exploratory analysis – Source: Genomics, Sep 4, 2008

  [ 66 votes ]   [ Discuss This Article ]
By Jim Fuite, Suzanne D. Vernon, Gordon Broderick • www.ProHealth.com • September 10, 2008


This work investigates the significance of changes in association patterns linking indicators of neuroendocrine and immune activity in patients with chronic fatigue syndrome (CFS).

Gene sets preferentially expressed in specific immune cell isolates were integrated with neuroendocrine data from a large population-based study.

Co-expression patterns linking immune cell activity with hypothalamic-pituitary-adrenal (HPA), thyroidal (HPT) and gonadal (HPG) axis status were computed using mutual information criteria.

Networks in control and CFS subjects were compared globally in terms of a weighted graph edit distance. Local re-modeling of node connectivity was quantified by node degree and eigenvector centrality measures.

Results indicate statistically significant differences between CFS and control networks determined mainly by re-modeling around pituitary and thyroid nodes as well as an emergent immune sub-network.

Findings align with known mechanisms of chronic inflammation and support possible immune-mediated loss of thyroid function in CFS exacerbated by blunted HPA axis responsiveness.

Source: Genomics, Sep 4, 2008. [E-pub ahead of print]. PMID: 18775774, by Fuite J, Vernon SD, Broderick G. The Chronic Fatigue and Immune Dystunction Syndromes (CFIDS) Association of America, Charlotte, NC, USA (Dr. Vernon); Department of Medicine, Division of Pulmonary Faculty of Medicine and Dentistry University of Alberta; Walter Mackenzie Health Sciences Centre, Edmonton, Alberta, Canada. [E-mail: gordon.broderick@ualberta.ca]





Post a Comment

Featured Products From the ProHealth Store
Ultra EPA  - Fish Oil Optimized Curcumin Longvida® Ultra ATP+, Double Strength

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
20 Helpful Tips for Cleaning and Organizing When You're Chronically Ill

Featured Products

Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium

Natural Remedies

The Surprising Benefits of Probiotics - What You Didn't Know The Surprising Benefits of Probiotics - What You Didn't Know
Anti-Inflammatory Properties of Tart Cherry Anti-Inflammatory Properties of Tart Cherry
Ubiquinol - A More Advanced Form of the Energy Producing Nutrient CoQ-10 Ubiquinol - A More Advanced Form of the Energy Producing Nutrient CoQ-10
When a Good Night's Sleep Is Just a Daydream... When a Good Night's Sleep Is Just a Daydream...
Undenatured Type II Collagen - Chicken Soup for Your Joints Undenatured Type II Collagen - Chicken Soup for Your Joints

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler

· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE AND SAVE 15% NOW*
Be the first to know about new products, special discounts and the latest health news. *New subscribers only

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map