ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Can Autoimmune Conditions be Reversed? Researchers Make a Surprising Discovery

Scientifically-designed fasting diet lowers risks for major diseases

How One Tiny Molecule Turned into One Huge Health Breakthrough

Acupuncture boosts effectiveness of standard medical care for chronic pain, depression

Research on Astaxanthin Demonstrates Significant Whole Body Benefits

Humans have three times more brown body fat

Nutrients Boost Stem Cell Function

B12 Proven Essential for Every Cell

Soy isoflavones may benefit breast cancer patients

Dietary prebiotics improve sleep, buffer impacts of stress, says study

 
Print Page
Email Article

Altered amino acid homeostasis in subjects affected by Fibromyalgia - Source: Clinical Biochemistry, Mar 9, 2009

  [ 6 votes ]   [ 2 Comments ]
By Laura Bazzichi, et al. • www.ProHealth.com • March 14, 2009


[Note: Amino acids are building blocks of the proteins responsible for virtually all metabolic activities in living cells. The body can produce 10 of these acids, but the other 10 (“essential” amino acids) must be supplied via protein in the diet or supplements. These can’t be stored, and failure to obtain even 1 of the essential 10 every day results in degradation of the body’s muscle & other proteins.]

Objectives: To evaluate plasma amino acids (AA) concentrations in patients affected by fibromyalgia (FM) and to study the relationships between their levels and FM clinical parameters.

Design and Methods: 20 amino acids were assessed in 34 FM patients and in 18 healthy volunteers by means of a modified version of the Waters picotag method.

Results: Significant lower plasma
• Taurine,
• Alanine,
• Tyrosine (Tyr),
• Valine,
• Methionine,
• Phenylalanine,
• Threonine concentrations
• And sum of essential amino acids were observed in FM patients vs. healthy controls (P<0.05).

Tyrosine CAAs [competing amino acids] ratio and the sum of amino acids competing with tryptophan for brain uptake resulted significantly reduced in FM (p<0.05).

Significant correlations were found between FM clinical parameters and certain amino acids.

Conclusion:

• Our results suggest a probable defects of gut malabsorption of certain amino acids in FM patients.

• Moreover, given the reduced Tyr CAAs ratio in FM patients, a possible impairment of catecholaminergic system in the FM syndrome may be suggested. [Catecholamines are substances derived from the amino acid tyrosine and produced in the medulla of the adrenal gland that act as neurotransmitters or hormones, such as dopamine and adrenaline.]

Source: Clinical Biochemistry, Mar 9, 2009. PMID: 19281806, by Bazzichi L, Palego L, Giannaccini G, Rossi A, De Feo F, Giacomelli C, Betti L, Giusti L, Bombardieri S, Lucacchini A. Department of Internal Medicine, Division of Rheumatology, University of Pisa, Pisa, Italy. [E-mail: l.bazzichi@int.med.unipi.it]





Post a Comment

Featured Products From the ProHealth Store
FibroSleep™ Optimized Curcumin Longvida® Mitochondria Ignite™ with NT Factor®

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments Post a Comment

RE:supplement
Posted by: limbo
Mar 15, 2009
Would you recommend a supplement of all amino acids or just the listed? Would we absorb them or is this a defect in fibromyalgia patients untreatable. I came upon this with interest as I feel this is what my instinct is directing me to.
Reply Reply

AMINO ACIDS
Posted by: Shirleend
Mar 17, 2009
Having been misdiagnosed with Fibromyalgia, I now know that I have a metabolic disorder that is specifically a problem with the process amino acids go through. Please, please take this study as a strong indication that if you have been diagnosed with Fibromyalgia/chronic fatigue, please get a plasma amino acid panel done before you take any supplements. Email me for any questions, Shirleen_D@hotmail.com
Reply Reply
 
NAD+ Ignite with Niagen

Featured Products

Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%

Natural Remedies

Breaking Through the Mental Fog Breaking Through the Mental Fog
Can Autoimmune Conditions be Reversed? Researchers Make a Surprising Discovery Can Autoimmune Conditions be Reversed? Researchers Make a Surprising Discovery
Ubiquinol - A More Advanced Form of the Energy Producing Nutrient CoQ-10 Ubiquinol - A More Advanced Form of the Energy Producing Nutrient CoQ-10
Itching to Find Dry Skin Relief? Itching to Find Dry Skin Relief?
Clinically Studied Joint Relief Product for FM & ME/CFS Clinically Studied Joint Relief Product for FM & ME/CFS

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map