ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

10 Fibro-Friendly Foods with a Bonus: Beautiful Skin

Fight Back! Win the War Being Waged Against Your Immune System

Studies Show that Magnesium L-threonate Improves Brain Plasticity, Leading to Direct and Significant...

Clary Sage Oil May Be Pricey, but Its Benefits Are Priceless

Component of red wine, grapes can help to reduce inflammation, study finds

Poly MVA: A Novel Therapy for Increasing Energy, Repairing DNA, and Promoting Overall Health

Pumpkin Pie Turmeric Breakfast Smoothie - Vegan + Gluten-Free

Vitamin D supplementation extends life in mouse model of Huntington's disease

What’s Fenugreek Good For?

Omega-3 fatty acid stops known trigger of lupus

Print Page
Email Article

Rice Researchers Develop First Fully Automatic Method to Track 3-D Movement of Cancer Cells

  [ 15 votes ]   [ Discuss This Article ] • September 17, 2002

Study could aid the development of cancer-slowing drugs

HOUSTON-- Sept. 16, 2002 -- Cancer researchers know the disease spreads from organ to organ in a non random pattern, but they are unable to predict exactly how cancer will spread, in part because of the limited tools available to study cancer cell migration in a controlled laboratory setting.

In groundbreaking new research, Rice University scientists have designed a computerized system that can track the movement of individual cancer cells growing in a three-dimensional culture of model living tissue. The system can be used to categorize the metastatic patterns of different cancers and to help test the effectiveness of cancer-slowing or proposed cancer prevention drugs.

Described in the current issue of Cancer Research, the Rice study involved experiments on two types of cancer cells -- a strain of breast cancer and a variant of skin cancer. The researchers placed cancer cells from each strain into two types of simulated soft tissue. Using computer automation, the researchers tracked and analyzed the movement of individual cells as they migrated through the tissue.

The skin cancer migrated faster, spread further and penetrated deeper in both types of tissue. However, the research also revealed similarities between the strains. For example, both types of cells showed a tendency to oscillate, burrowing into tissue, reversing briefly and burrowing back along a slightly different vertical path. This suggests that both types of cancer invade tissue by seeking or creating a path of least resistance.

"The most important element of this work is not the differences we observed in the metastatic patterns of these two types of cancer, it's the methodology we developed to study the movement of cancer cells in living tissue," said study co-author Larry McIntire, chair of Rice's Institute of Biosciences and Bioengineering. "Studying tumor cell invasion in live cultures in real time is a significant advance."

Only with in vitro studies of 3-D cell migration can scientists gather data on critical factors that influence metastasis, including:

* the percentage of mobile cells in a specific cancer strain
* the speed of cell movement
* the direction that cells move
* how long cells move in a particular direction
* how often cells turn and in which direction
* the way movement changes in reaction to chemicals or obstructions

McIntire's co-author on the ararticle is Zoe N. Demou, now a post-doctoral fellow at the Steele Laboratory for Tumor Biology at Harvard Medical School in Boston.

Cancer Research, published by the American Association for Cancer Research, is the most frequently cited cancer journal in the world and among the 15 most-cited scientific journals in the world.

Contact: Jade Boyd, email:,
Rice University

Post a Comment

Featured Products From the ProHealth Store
Vitamin D3 Extreme™ Ultra EPA  - Fish Oil Optimized Curcumin Longvida®

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products

Article Comments

Be the first to comment on this article!

Post a Comment

Natural Pain Relief Supplements

Featured Products

FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils

Natural Remedies

Cocoa's Polyphenol Riches - All the Health Benefits without the Sugar, Calories or Guilt Cocoa's Polyphenol Riches - All the Health Benefits without the Sugar, Calories or Guilt
Anti-Inflammatory Properties of Tart Cherry Anti-Inflammatory Properties of Tart Cherry
Red Yeast Rice - Natural Option for Supporting Healthy Cholesterol Red Yeast Rice - Natural Option for Supporting Healthy Cholesterol
Itching to Find Dry Skin Relief? Itching to Find Dry Skin Relief?
The Revolutionary 'Good Fat' That Promotes Heart, Brain, Bone and Joint Health The Revolutionary 'Good Fat' That Promotes Heart, Brain, Bone and Joint Health

ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
Credit Card Processing
Be the first to know about new products, special discounts and the latest health news. *New subscribers only

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map