ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Can Autoimmune Conditions be Reversed? Researchers Make a Surprising Discovery

How One Tiny Molecule Turned into One Huge Health Breakthrough

Nutrients Boost Stem Cell Function

Humans have three times more brown body fat

B12 Proven Essential for Every Cell

Soy isoflavones may benefit breast cancer patients

How B Vitamins Improve Brain Health, Cognition, Psychiatric Problems and Mood Disorders

Dietary prebiotics improve sleep, buffer impacts of stress, says study

Ylang Ylang Oil Not Only Soothes Your Skin, but Your Mind as Well

Exercises to Help Prevent Urinary Incontinence

 
Print Page
Email Article

Efficacy and Safety Study of the Experimental Drug Aplindore in Patients With Restless Legs Syndrome – Now Recruiting Across the U.S.

  [ 5 votes ]   [ Discuss This Article ]
www.ProHealth.com • April 17, 2009


24 trial sites in 15 states are recruiting a total of 230 patients with moderate to severe restless legs syndrome for a six-week trial of the controlled release drug aplindore MS.

The trial targets 230 patients, who will be randomly assigned to five groups – four groups taking different dosages of the drug and one group taking a placebo (fake dose).

In a previous phase 2 trial for RLS symptoms, a 0.05 mg “starting dose” of aplindore reportedly achieved “statistically significant efficacy,” possibly indicating the drug may be better tolerated and not require the slow phasing in or titration needed with drugs now prescribed for RLS. As a “dopamine partial agonist,” aplindore activates dopamine receptors, but to a lesser extent than a full dopamine agonist. (The neurotransmitter dopamine has been shown to reduce RLS symptoms. It is responsible for arousal or alertness, by comparison with serotonin, which relaxes.)

• Patients ages 18-85 of both sexes may be eligible for the trial.

• Symptoms must be moderate to severe, disrupting sleep for at least 3 nights per week for a least 3 months,

• And the person must be off dopamine agonists or other meds taken for RLS for a specified period before Day 1 of the trial.

For more information about the trial and locations of the trial sites, and to contact the trial organizers, visit the ClinicalTrials.gov site for Efficacy and safety Study of Aplindore in Patients with Restless Legs Syndrome, Identifier NCT00834327




Post a Comment

Featured Products From the ProHealth Store
Ultra EPA  - Fish Oil Ultra ATP+, Double Strength FibroSleep™

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
NAD+ Ignite with Niagen

Featured Products

Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%

Natural Remedies

SAD? Coping with Seasonal Affective Disorder SAD? Coping with Seasonal Affective Disorder
Cocoa's Polyphenol Riches - All the Health Benefits without the Sugar, Calories or Guilt Cocoa's Polyphenol Riches - All the Health Benefits without the Sugar, Calories or Guilt
The Fast-Acting Solution for Healthy Digestive Function The Fast-Acting Solution for Healthy Digestive Function
D-ficient? Health Risks You Need to Know About D-ficient? Health Risks You Need to Know About
Rejuvenating the Brain - How PQQ Helps Power Up Mental Processing Rejuvenating the Brain - How PQQ Helps Power Up Mental Processing

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map