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Detection of herpesviruses and parvovirus b19 in gastric and intestinal mucosa of chronic fatigue syndrome patients – Source: In Vivo, Mar-Apr 2009

  [ 7 votes ]   [ 3 Comments ]
By M Fremont, K De Meirleir, et al. • www.ProHealth.com • May 6, 2009


Background: Human herpesvirus-6 (HHV-6), Epstein-Barr virus and parvovirus B19 have been suggested as etiological agents of chronic fatigue syndrome, but none of these viruses is consistently detected in all patients.

However, active viral infections may be localized in specific tissues, and, therefore, are not easily detectable.

The aim of this study was to investigate the presence of HHV-6, HHV-7, EBV and parvovirus B19 in the gastro-intestinal tract of CFS patients.

Patients and Methods: Using real-time PCR, viral DNA loads were quantified in gastro-intestinal biopsies of 48 CFS patients and 35 controls.

Results:

• High loads of HHV-7 DNA were detected in most CFS and control biopsies. EBV and HHV-6 were detected in 15%-30% of all biopsies.

• Parvovirus B19 DNA was detected in 40% of the patients versus less than 15% of the controls.

Conclusion:

Parvovirus B19 may be involved in the pathogenesis of CFS, at least for a subset of patients.

The gastro-intestinal tract appears as an important reservoir of infection for several potentially pathogenic viruses.

Source: In Vivo, Mar-Apr 2009;23(2):209-13. PMID: 19414405, by Frémont M, Metzger K, Rady H, Hulstaert J, De Meirleir K. Protea Biopharma, Zellik, Belgium. [E-mail: mfremont@proteabiopharma.com]




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Article Comments Post a Comment

Epstein-Barr virus, very interesting !
Posted by: tuuli
May 20, 2009
I have tested positive for Epstein-barr and also have been re-activated by the same virus.I have been having chronic fatigue on and off for the past 20 years and always have gastric problems assosiated with everything else. Do you have answers for the cure ? I am getting older and would love to be feeling better.
Reply Reply

Epstein Barr Virus
Posted by: angel_wings1953
May 22, 2009
After being in and out of work for many weeks and blood work coming back with possible virus, I finally tested positive for EBV. They say it is very much like having Mono and a kin to it. I can agree with that. But it seemed I just went down hill after that, Fibro diagnosed finally, pain, Fibro Fog, Fatigue, etc. Finally, had to go on disability. Of which I'm still awaiting a hearing.
Reply Reply

Epstein Barr Virus & Fibro
Posted by: angel_wings1953
May 22, 2009
After being in and out of work for many weeks and blood work coming back with possible virus, I finally tested positive for EBV. They say it is very much like having Mono and a kin to it. I can agree with that. But it seemed I just went down hill after that, Fibro diagnosed finally, pain, Fibro Fog, Fatigue, IBS-D etc. Finally, had to go on disability. Of which I'm still awaiting a hearing. I have other symptoms as well for Fibro and pain in back and neck from past injuries as well as Degenerative Discs.
Reply Reply


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