ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Increase Your Magnesium Intake

Vitamin D supplementation could ease IBS symptoms

Top Tips to Boost Your Immunity

11 Amazing Health Benefits of Using Baking Soda

Nicotinamide riboside shows promise for treatment of Alzheimer’s disease

Exercise, calcium, vitamin D, and other factors linked with fewer injurious falls

Vitamin D3 Is a Powerhouse for Your Heart

Rhodiola — A Powerful Adaptogen That Boosts Vitality and Performance, Eases Depression and Combats B...

Curcumin Supplementation May Impart Long-Term Cognitive Benefits

Vitamin D deficiency during pregnancy can program obesity in children

 
Print Page
Email Article

Omega-3 Fatty Acids [fish oil] and Dementia - Source: Prostaglandins, Leukotrienes, and Essential Fatty Acids, Jun 10, 2009

  [ 32 votes ]   [ Discuss This Article ]
By Gregory M Cole, et al. • www.ProHealth.com • June 19, 2009


More than a dozen epidemiological studies have reported that reduced levels or intake of omega-3 fatty acids or fish consumption is associated with increased risk for age-related cognitive decline or dementia such as Alzheimer's disease (AD).

Increased dietary consumption or blood levels of docosahexaenoic acid (DHA) appear protective for Alzheimer's disease and other dementia in multiple epidemiological studies; however, three studies suggest that the ApoE4 genotype limits protection.

DHA is broadly neuroprotective via multiple mechanisms that include:
• Neuroprotective DHA metabolites,
• Reduced arachidonic acid metabolites,
• And increased trophic factors or downstream trophic signal transduction.

DHA is also protective against several risk factors for dementia including:
• Head trauma,
• Diabetes,
• And cardiovascular disease.

DHA is specifically protective against Alzheimer’s disease via additional mechanisms:
• It limits the production and accumulation of the amyloid beta peptide toxin that is widely believed to drive the disease;
• And it also suppresses several signal transduction pathways induced by Abeta, including two major kinases that phosphorylate the microtubule-associated protein tau and promote neurofibrillary tangle pathology.

Based on the epidemiological and basic research data, expert panels have recommended the need for clinical trials with omega-3 fatty acids, notably DHA, for the prevention or treatment of age-related cognitive decline - with a focus on the most prevalent cause, Alzheimer’s disease.

Clinical trials are under way to prevent and treat Alzheimer’s disease. Results to date suggest that DHA may be more effective if:
• It is begun early
• Or used in conjunction with antioxidants.

Source: Prostaglandins, Leukotrieines, and Essential Fatty Acids, Jun 10, 2009. PMID: 19523795, by Cole GM, Ma OL, Frautschy SA. Department of Medicine and Department of Neurology at University of California, Los Angeles; GRECC Veterans Affairs, Greater Los Angeles Healthcare System, North Hills, California, USA. [E-mail: gmcole@ucla.edu]





Post a Comment

Featured Products From the ProHealth Store
Ultra ATP+, Double Strength Energy NADH™ 12.5mg Mitochondria Ignite™ with NT Factor®


Article Comments



Be the first to comment on this article!

Post a Comment


 
Optimized Curcumin Longvida with Omega-3

Featured Products

Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get Energized with Malic Acid & Magnesium
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function

Natural Remedies

Everything You Always Wanted to Know About Sleep But Were Too Tired to Ask Everything You Always Wanted to Know About Sleep But Were Too Tired to Ask
Live Without Anxiety or Stress Live Without Anxiety or Stress
Enhance Eyelashes Naturally Enhance Eyelashes Naturally
Health Benefits Are Brewing in Green Tea Health Benefits Are Brewing in Green Tea
Anti-Inflammatory Properties of Tart Cherry Anti-Inflammatory Properties of Tart Cherry

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2018 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map