ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

15 Health Benefits of Chia Seeds, According to Science

Tangerine Oil: A Citrusy Essential Oil With Well-Rounded Uses

Natural Remedies for the Prevention of Dry Eyes

Magnesium Deficiency Raises Your Risk of Many Chronic Ailments

Resveratrol supplementation improves arterial stiffness in type 2 diabetics

CoQ10's Potential Capabilities for Your Health

How Can Melatonin Benefit You?

Cloves: Boost Your Immune System the Sweet and Spicy Way

Testosterone replacement therapy associated with improved urinary, sexual function

8 Chia Seed Recipes

 
Print Page
Email Article

Gene That Regulates Development Of Heart Cells Identified, Described By Penn Researchers

  [ 5 votes ]   [ Discuss This Article ]
www.ProHealth.com • September 20, 2002


Philadelphia, PA -- Scientists at the University of Pennsylvania School of Medicine have identified and described a small gene that regulates the delicate balance involved in the healthy growth and replication of heart muscle cells.

"This finding is likely to be important for our understanding of the causes of congenital heart disease. It is also relevant to our attempts to regrow damaged heart muscle," said the corresponding author of the study, Jonathan A. Epstein, MD, of Penn's Departments of Medicine and Cell & Developmental Biology. The study is scheduled to appear in the September 20 issue of the journal Cell.

The newly identified heart gene, Hop (an acronym for homeodomain only protein), is a small protein that lacks certain residues required for DNA binding, but is activated early in fetal development and continues modulating the expression of cardiac-specific genes throughout life. Hop appears to bind directly to another important regulator of development, serum response factor (SRF), and block SRF from binding to DNA. By inhibiting the expression of SRF, Hop protects cardiac muscle cells from over-development, and from developing fatal abnormalities.

"There has been a lot of effort to try to determine how SRF is regulated in different tissues," Epstein said. "Now we see that Hop plays a vital part."


The study was funded by the National Institutes of Health, the American Heart Association, and the W.W. Smith Foundation.

Others who participated in the research are: Fabian Chen, MD; Hyun Kook, MD; Rita Milewski, MD; Aaron D. Gitler, MD; Min Min Lu, MD; Jun Li, MD; Ronniel Nazarian, MD; Robert Schnepp, MD; Kuangyu Jen, MD; Greg Runke, MD, and Mary C, Mullins, MD, all of Penn; Christine Biben, MD; Joel P. Mackay, MD, Jiri Novotny, MD, all of the Victor Chang Cardiac Research Institute, Carlinghurst, Australia; Robert Schwartz, MD, of Baylor College of Medicine, Houston, TX, and Richard P. Harvey, MD, of the Chang Institute and the University of New South Wales, Australia.






Post a Comment

Featured Products From the ProHealth Store
Optimized Curcumin Longvida® Ultra EPA  - Fish Oil Energy NADH™ 12.5mg


Article Comments



Be the first to comment on this article!

Post a Comment


 
Optimized Curcumin Longvida with Omega-3

Featured Products

Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function

Natural Remedies

Fight Inflammation and Promote Cognitive Health with High-OPC Grape Seed Fight Inflammation and Promote Cognitive Health with High-OPC Grape Seed
Research Links Green Tea to Weight Loss Research Links Green Tea to Weight Loss
D-ficient? Health Risks You Need to Know About D-ficient? Health Risks You Need to Know About
Natural Bladder Control, Go Less and Live More Natural Bladder Control, Go Less and Live More
Aching Muscles? Top 10 Nutrients to Take Back Your Life Aching Muscles? Top 10 Nutrients to Take Back Your Life

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map