ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Is Magnesium the Missing Link in Your Heart Healthy Routine?

A Little Zinc Goes a Long Way

Supplementation with vitamin D associated with improved testosterone, erectile function among middle...

More evidence for calorie restriction’s longevity effect

Vitamin D deficiency increases risk of chronic headache

Wearable biosensors can flag illness, Lyme disease, risk for diabetes; low airplane oxygen

VIDEO: The Best Brain Foods That Help Increase Your Memory!

Iron (And More) For Lasting, Natural Energy

Get the Most From Your Green Tea

Affordable Care Act made cancer screening more accessible for millions, study finds

 
Print Page
Email Article

Omega-3 Levels Linked to Speed of Biological Aging

  [ 30 votes ]   [ 2 Comments ]
www.ProHealth.com • January 19, 2010


Omega-3 fatty acids may protect against cellular aging, according to a 5-year tracking study published Jan 19 in JAMA.(1)

The study of patients with cardiovascular disease found that higher omega-3 fatty acid blood levels were associated with less shortening of the telomeres – ‘caps’ on the ends of chromosomes that protect them from deterioration and are emerging as a marker of biological age.

Several studies have also shown increased survival rates among individuals with established cardiovascular disease who consume generous amounts of marine omega-3 fatty acids (fish & krill oil).

It is known that telomeres are involved in the replication and stability of the chromosome, and that genetic factors and environmental stressors can shorten them. But the mechanisms underlying the omega-3 oils’ protective effect are not well understood, according to background information in the article.

Ramin Farzaneh-Far, MD, of the University of California, San Francisco, and colleagues conducted a study to determine whether omega-3 fatty acid blood levels were associated with changes in leukocyte (a type of blood cell) telomere length in a study of 608 outpatients with stable coronary artery disease. The patients were recruited between September 2000 and December 2002 for the Heart and Soul Study, and followed up to January 2009 (median [midpoint], 6.0 years).

The researchers measured leukocyte telomere length at the beginning of the study and again after 5 years of follow-up. Multivariable models were used to examine the association of baseline levels of omega-3 fatty acids (docosahexaenoic acid [DHA] and eicosapentaenoic acid [EPA]) with subsequent change in telomere length.

The researchers found that individuals in the lowest quartile of DHA+EPA experienced the most rapid rate of telomere shortening, whereas those in the highest quartile experienced the slowest rate of telomere shortening.

“Levels of DHA+EPA were associated with less telomere shortening before and after sequential adjustment for established risk factors and potential confounders,” the researchers write. "Each 1-standard deviation increase in DHA+EPA levels was associated with a 32 percent reduction in the odds of telomere shortening.

"In summary, among patients with stable coronary artery disease, there was an inverse relationship between baseline blood levels of marine omega-3 fatty acids and the rate of telomere shortening over 5 years. These findings raise the possibility that omega-3 fatty acids may protect against cellular aging in patients with coronary heart disease.”
___
1. Article cited: “Association of marine omega-3 fatty acid levels with telomeric aging in patients with coronary heart disease,”   Rarzaney-Far R, et al., JAMA, Jan 20, 2010.

Source: American Medical Association news release, Jan 19, 2009




Post a Comment

Featured Products From the ProHealth Store
Ultra EPA  - Fish Oil

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments Post a Comment

JAMA 2010; 303: 250-257: Omega-3 Fatty Acids and Telomeres in Coronary Heart Disease
Posted by: James Michael Howard
Jan 20, 2010
JAMA. 2010;303(3):250-257: Association of Marine Omega-3 Fatty Acid Levels With Telomeric Aging in Patients With Coronary Heart Disease It is my hypothesis that DHEA was selected by evolution because it optimizes replication and transcription of DNA. Therefore, all tissues will be affected by the reduction in DHEA which naturally begins around age twenty, reaching very low levels in old age. Low DHEA will be involved in coronary artery disease. It has been determined that docosahexaenoic acid positively affects levels of DHEA in a "concentration-dependent" manner (J Vet Med Sci. 2007 Jan;69(1):49-54). I wrote a paper explaining the connection of DHEA and telomere length in 2004: http://anthropogeny.com/Telomeres.htm . I suggest these findings may be explained by increases in DHEA and that the benefits of fish oil, that is, docosahexaenoic acid, are due to increases in DHEA. James Michael Howard, Fayetteville, Arkansas, U.S.A.
Reply Reply

JAMA 2010; 303: 250-257: Omega-3 Fatty Acids and Telomeres in Coronary Heart Disease
Posted by: James Michael Howard
Jan 20, 2010
JAMA. 2010;303(3):250-257: Association of Marine Omega-3 Fatty Acid Levels With Telomeric Aging in Patients With Coronary Heart Disease It is my hypothesis that DHEA was selected by evolution because it optimizes replication and transcription of DNA. Therefore, all tissues will be affected by the reduction in DHEA which naturally begins around age twenty, reaching very low levels in old age. Low DHEA will be involved in coronary artery disease. It has been determined that docosahexaenoic acid positively affects levels of DHEA in a "concentration-dependent" manner (J Vet Med Sci. 2007 Jan;69(1):49-54). I wrote a paper explaining the connection of DHEA and telomere length in 2004: http://anthropogeny.com/Telomeres.htm . I suggest these findings may be explained by increases in DHEA and that the benefits of fish oil, that is, docosahexaenoic acid, are due to increases in DHEA. James Michael Howard, Fayetteville, Arkansas, U.S.A.
Reply Reply
 
NAD+ Ignite with Niagen

Featured Products

Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils

Natural Remedies

Cocoa's Polyphenol Riches - All the Health Benefits without the Sugar, Calories or Guilt Cocoa's Polyphenol Riches - All the Health Benefits without the Sugar, Calories or Guilt
Aching Muscles? Top 10 Nutrients to Take Back Your Life Aching Muscles? Top 10 Nutrients to Take Back Your Life
Nutrients to Combat the Modern Stress Epidemic Nutrients to Combat the Modern Stress Epidemic
Energy Breakthrough - One Fibromyalgia Patient’s Fortuitous Discovery Energy Breakthrough - One Fibromyalgia Patient’s Fortuitous Discovery
Prepare Yourself for Cold & Flu Season Prepare Yourself for Cold & Flu Season

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map