ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

10 Fibro-Friendly Foods with a Bonus: Beautiful Skin

Fight Back! Win the War Being Waged Against Your Immune System

Studies Show that Magnesium L-threonate Improves Brain Plasticity, Leading to Direct and Significant...

Clary Sage Oil May Be Pricey, but Its Benefits Are Priceless

Component of red wine, grapes can help to reduce inflammation, study finds

Poly MVA: A Novel Therapy for Increasing Energy, Repairing DNA, and Promoting Overall Health

Pumpkin Pie Turmeric Breakfast Smoothie - Vegan + Gluten-Free

Vitamin D supplementation extends life in mouse model of Huntington's disease

Omega-3 fatty acid stops known trigger of lupus

Conquer Your Email Inbox, Increase Productivity and Reduce Stress

Print Page
Email Article

National Research Study Seeks Female Lupus Patients & Their Sisters

  [ 12 votes ]   [ Discuss This Article ] • March 30, 2010

The nationwide study invites women ages 10 to 35 diagnosed with lupus if they have one or more sisters/half sisters ages 10 to 35 without a diagnosis of lupus.

Scientists at The Feinstein Institute for Medical Research have embarked on a national search for sisters.

The SisSLE (Sisters of Women with Systemic Lupus Erythematosus) research study is looking for sisters: one with a diagnosis of systemic lupus erythematosus (SLE), an autoimmune disease, and one (or more) who does not have lupus.

Betty Diamond, MD, and Peter Gregersen, MD, designed the study to understand how individuals may progress to lupus. By following sister(s) of a lupus patient the hope is to identify the disease in its earliest, pre-symptomatic stage and track its progression over time.

The pilot study will enroll 400 sisters over a 2-year period.

• Scientists will be able to identify auto-antibodies that play a role in lupus and study other changes in blood serum that may help predict disease.

• They will also be trying to figure out how auto-antibodies may interact with environmental factors to play a role in the development of lupus.

Lupus is nine times more common in women and the autoimmune disease can attack many different organs and tissues of the body. Lupus has a significant genetic component.

• The risk of developing SLE is 0.1 percent in the population and twice that in females.

• In first degree relatives the risk can be from 4 to 8 percent.

The Feinstein’s Dr. Diamond, a world-renowned lupus researcher and director of the Center for Autoimmune and Musculoskeletal Disorders, is teaming up with geneticist Peter K. Gregersen, MD, who is director of the Robert S. Boas Center for Genomics and Human Genetics.

They want to understand how people progress from the start of the autoimmune process to end up with severe disability.

What scientists know about the epidemiology of the illness is this:

• If they follow 4,000 sisters with a sibling with lupus that 80 of them will develop the autoimmune disease at some point in their lives.

• They also know that some sisters with anti-DNA antibody in their blood will never get lupus. The question is why.

Ultimately they want to figure out who those people are and whether the auto-antibodies in their blood can reveal something about why they got sick or not.

• Then, what if they can begin treating people at risk for lupus before the disease causes organ damage?

• Could they stave off more serious symptoms and provide people with a better quality of life?

They are hoping that this study will be able to help fit these puzzle pieces together.

This study will be a collaborative effort nationwide.

• There may be more than half a million lupus patients and more than half will have been diagnosed before their 35th birthday.

• By crude estimates, it means that there are 300,000 people who got lupus in their 30s.

• If 70 percent have a sister that means that they have a population of 200,000 potential recruits for the study.

• They are ultimately looking to recruit 4,000 sisters.

The plan is to also mine the genome to identify genes that put families at risk and start to link the various genes to the different symptoms of the disease.

The sisters who have anti-nuclear antibodies but no signs of disease will also help tell the story of how the body’s immune system fends off this autoimmune disease.

• Can they identify markers of progression to disease?

• Who will get lupus and when?

“The healthy person will help us understand the disease,” Dr. Diamond said.

For more information call Bonnie Gonzales, RN, or Sally Kaplan, RN, at 877-698-9467 or email or visit the website

Source: North Shore-Long Island Jewish Health System news release, Mar 29, 2010

Post a Comment

Featured Products From the ProHealth Store
FibroSleep™ Ultra ATP+, Double Strength Mitochondria Ignite™ with NT Factor®

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products

Article Comments

Be the first to comment on this article!

Post a Comment

Natural Pain Relief Supplements

Featured Products

Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils

Natural Remedies

Cell-Charging Compound Gives Steady Energy to Fibromyalgia & Chronic Fatigue Patients Cell-Charging Compound Gives Steady Energy to Fibromyalgia & Chronic Fatigue Patients
Strengthen Cell Function with Energy-Boosting Niagen Strengthen Cell Function with Energy-Boosting Niagen
Physically and Mentally Exhausted? How to Restore Energy at Its Source Physically and Mentally Exhausted? How to Restore Energy at Its Source
Carry a Massage Therapist in Your Pocket Carry a Massage Therapist in Your Pocket
Strontium - The Missing Mineral for Strong Bones Strontium - The Missing Mineral for Strong Bones

ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
Credit Card Processing
Be the first to know about new products, special discounts and the latest health news. *New subscribers only

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map