Activate Now
 
ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Chocolate's Potential Health Benefits – and its Effect on Chronic Fatigue Syndrome Patients

High dose vitamin D3 supplementation lowers inflammatory T cells in multiple sclerosis patients

Repair Damaged Mitochondria and Reduce Fatigue Up to 45%

Essential Oils - How and Where to Use Them

The Link Between Vitamin C And Optimal Immunity

SURVEY: What Is Your Diagnosis?

Liposomes Deliver Optimal Nutrient Absorption

Why Does Your Nose Run When It's Cold Outside?

What's So Great About Grape Seed?

How Your Mitochondria Influence Your Health

 
Print Page
Email Article

Capsaicin patch for long-lasting post-shingles pain relief now available

  [ 32 votes ]   [ Discuss This Article ]
www.ProHealth.com • April 7, 2010


A single one-hour localized, office-applied treatment with prescription-strength 8% capsaicin (a synthetic form of the ‘heat’-producing compound found in chili peppers) can provide three months relief from postherpetic neuralgia – (PHN), the ‘nerve pain’ that can follow shingles.

Originally limited to over-the-counter, lower-strength topical applications, capsaicin works by depleting or interfering with substance P, a chemical that transmits pain impulses along nerve pathways to the brain. The drug (Qutenza®) was FDA approved in Nov 2009 for management of neuropathic pain associated with postherpetic neuralgia. Potentially useful for HIV neuropahy and diabetic neuropathy as well based on early testing, the drug is:

•  Locally-acting

•  Non-narcotic,

•  Unlikely to cause drowsiness or interact with other drugs.

•  And can be used alone or with other pain medications.

What is Post Herpetic Pain?
Each year, about one million Americans develop shingles, a painful viral infection caused by a reactivation of the same virus that causes chickenpox. It is estimated that up to one in five people with shingles will experience prolonged pain after shingles, known as PHN. The pain can persist long after the shingles rash clears up and can disrupt sleep, mood, work and the activities of daily living.

“PHN can be an excruciatingly painful condition that can greatly affect many aspects of a person’s daily living,” said Lynn Webster, MD, medical director, Lifetree Clinical Research, Salt Lake City, Utah. “Despite the current availability of a variety of pain medications, undesirable side effects, such as drowsiness and interactions with other drugs, often limit their use.

“Because of these limitations, there is still a need for new treatment options for PHN, and, more importantly, many patients are still suffering. Qutenza may provide a unique treatment option for patients. It is targeted directly to the site of the pain and may be used alone or in combination with existing therapies.”

One-Hour Application, Lasting Effect

Qutenza is applied directly to the painful site by a physician, or health care professional under the close supervision of a physician.

•  Applied to marked areas on the skin, the treatment is accompanied by a numbing agent applied to these areas, possibly along with cold packs and pain medicine. (The initial effect of application is an intense burning sensation, which later subsides.)

•  Up to four patches may be used.  

•  They may be cut to conform to the size and shape of the painful area.  

•  Treatment may be repeated every three or more months as warranted by the return of pain,

•  But not more frequently than every three months.

Side Effects
In clinical trials, the most common side effects were application-site redness, pain, itching, and papules (small bumps). The majority of these reactions were local, transient and self limited. Among patients treated with Qutenza, 1 percent discontinued prematurely due to an adverse event. Serious adverse reactions included application-site pain and increased blood pressure.

Increases in blood pressure occurred during or shortly after exposure to Qutenza and were associated with treatment-related increases in pain. The changes were on average less than 10 mm Hg, although some patients had greater increases, and these changes lasted for approximately two hours after patch removal.

Educational in-service training will be available online and on DVD for health care professionals interested in prescribing and administering the drug; and patients will be able to locate doctors who may prescribe the drug at Qutenza.com.

Another Capsaicinoid in Trials for Advanced Cancer Pain
Another high strength capsaicin compound (Resiniferatoxin), from the sap of a Moroccan plant is now in NIH-funded human trials as a potential morphine alternative for severe advanced cancer pain. At 1,000 times the potency of capsaicin in chilis, this experimental drug does more than numb neurons in the pain messaging system; it ‘shatters’ and kills them. Injected under general anesthesia in the spinal cord of dogs with bone cancer in earlier animal trials, it enabled the animals to move and play again, apparently pain free, for weeks to months.
___
Sources: NeurogesX, Inc. news release Apr 6; Southern Illinois University School of Medicine news release, Nov 3, 2009.




Post a Comment

Featured Products From the ProHealth Store
Mitochondria Ignite™ with NT Factor® FibroSleep™ Vitamin D3 Extreme™

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS, Fibromyalgia & Lyme Disease treatment and research news
 Privacy Guaranteed  |  View Archives

How Glutathione Can Save Your Life

Featured Products

Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health

Natural Remedies

Astaxanthin - A Little-Known but Power-Packed Nutrient Astaxanthin - A Little-Known but Power-Packed Nutrient
Fighting Fatigue with Ground-breaking French Oak Wood Extract Fighting Fatigue with Ground-breaking French Oak Wood Extract
Prepare Yourself for Cold & Flu Season Prepare Yourself for Cold & Flu Season
The Most Powerful Natural Antioxidant Discovered to Date - Hydroxytyrosol The Most Powerful Natural Antioxidant Discovered to Date - Hydroxytyrosol
Sleep Like a Baby in Nature's Cradle Sleep Like a Baby in Nature's Cradle

FIBROMYALGIA
What is Fibromyalgia?
Fibromyalgia Diagnosis
Fibromyalgia Symptoms
Fibromyalgia Causes
Fibromyalgia Treatments
Fibromyalgia Diet
Fibromyalgia Medications
M.E. & CFS
What is M.E./CFS?
M.E./CFS Diagnosis
M.E./CFS Symptoms
M.E./CFS Causes
M.E./CFS Treatments
M.E./CFS Diet
M.E./CFS Medications
LYME DISEASE
What is Lyme Disease?
Lyme Disease Diagnosis
Lyme Disease Symptoms
Lyme Disease Causes
Lyme Disease Treatments
Lyme Disease Diet
Lyme Disease Medications
FORUMS
Fibromyalgia
M.E. & CFS
Lyme Disease
General Health
WHOLESALE
AFFILIATES GUARANTEE
PRIVACY
CONTACT US
LIBRARY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing