ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Vitamin D supplements, sleep could help manage pain

Bacopa: The Herb That May Increase Your Brain Power

Eat More Yogurt and Avoid Osteoporosis

Lilac Oil: More Than Just for Fragrance

Coffee, herbal tea may help prevent liver fibrosis

Crafty Uses for Carrot Seed Oil

Higher omega 3 levels linked to improved brain blood flow

Curcumin, resveratrol, ursolic acid show promise against prostate cancer

Olive oil compound could help protect against brain cancer

Probiotic use linked to improved symptoms of depression

 
Print Page
Email Article

Emory reports developing diagnostic test for XMRV infection – finds the retrovirus infects some prostate cancer patients

  [ 42 votes ]   [ 1 Comment ]
www.ProHealth.com • April 8, 2010


“This assay has been rigorously confirmed by two independent labs and two independent technologies (PCR and FISH); thus confidence in the accuracy of the test is high.”

The recently discovered retrovirus, xenotropic murine leukemia virus-related virus (XMRV), has been identified in some prostate cancer patients. In light of conflicting data concerning XMRV, standardized diagnostic testing is important to identify patients in which XMRV is present and to determine whether it plays a role in the incidence of prostate cancer.

An article published in the April issue of Urology® is a step in this direction as researchers from Emory University report the successful development of an experimental clinical test for XMRV. To read the free full text article (“XMRV Infection in Patients With Prostate Cancer: Novel Serologic Assay and Correlation With PCR and FISH”) click here.

"We cannot as a scientific community begin to answer the basic questions of XMRV transmission, frequency in the population, association with disease, etc. until we can effectively test for infection," according to lead investigator John A. Petros, MD, Associate Professor of Urology, Emory University School of Medicine and Veterans Administration Hospital.

Dr. Petros and co-investigators adapted technology developed in the HIV arena (neutralizing antibody assay) and have developed a serum test that can identify patients who have previously been infected with the virus. This assay has been rigorously confirmed by two independent labs and two independent technologies (PCR and FISH), thus confidence in the accuracy of the test is high.

The mode of transmission of the virus is unknown. No method is available to screen either blood or tissue donors for infection and no data are available regarding whether the virus can be transmitted by blood transfusion or tissue transplantation.

Dr. Petros comments, "The public deserves to know if the next blood transfusion or organ donation will give them XMRV retrovirus, an infection which lasts for life, and could possibly be related to prostate cancer. The failure to develop accurate tests for this virus is a serious public health oversight."

Although the assay used in the present report involved the inhibition of infection of target cells by viral-like particles with the XMRV envelope protein expressed on their surface, results also suggest that more standard serologic tests for antibodies against specific viral antigens can be developed in the future.

The authors conclude that:

"Our report adds to the growing body of evidence that XMRV is indeed a novel gamma-retrovirus capable of infecting humans and that at least some patients with prostate cancer have been infected with XMRV. We have reported serologic evidence of infection and that the serology correlated with tissue-based assays.

“The concordance of 3 independent methods of detecting infection added confidence to the assertion that this recently discovered virus is real and possibly related to human disease.

“Robust clinical assays are needed to detect XMRV infection, and much work remains to be done in determining whether XMRV is indeed an oncogenic [tumor-causing] virus or simply an associated epiphenomenon."

___
Source: Elsevier Health Sciences news release, Apr 5, 2010




Post a Comment

Featured Products From the ProHealth Store
Optimized Curcumin Longvida® Ultra EPA  - Fish Oil Vitamin D3 Extreme™

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments Post a Comment

XMRV test
Posted by: olyred
Apr 14, 2010
Well, it would have been helpful to know how to obtain this test.
Reply Reply
 
NAD+ Ignite with Niagen

Featured Products

Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium

Natural Remedies

Improve Cardiovascular and Metabolic Health with Omega-7 Improve Cardiovascular and Metabolic Health with Omega-7
Aches and Pains? A Simple Solution You'll Love Aches and Pains? A Simple Solution You'll Love
Nutrients to Combat the Modern Stress Epidemic Nutrients to Combat the Modern Stress Epidemic
Fatigue & Fibro Fog: Could You Have a B-12 Deficiency? Fatigue & Fibro Fog: Could You Have a B-12 Deficiency?
Natural Bladder Control, Go Less and Live More Natural Bladder Control, Go Less and Live More

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map