ProHealth health Vitamin and Natural Supplement Store and Health
Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

|
|
|
|

Trending News

Missing protein explains link between obesity, diabetes

Single tick bite can pack double pathogen punch

Fish oil use associated with brain volume preservation

The Brain Boosting and Fatigue Fighting B-12

Genetic basis for distinct type of autism uncovered

Higher vitamin D levels associated with better cancer prognosis

Genetic study suggests causal link between vitamin D deficiency and hypertension

Unsuspected aspect of immune regulation revealed: Role of B cells

Explaining 'Healthy' Obesity

IBS, Crohn’s Disease, Colitis, and Other Digestive Disorders

 
Print Page
Email Article

EPA [fish oil] supplementation improves teacher rated behavior and oppositional symptoms in children with ADHD – Source: Acta Paediatrica, May 19, 2010

  [ 23 votes ]   [ Post a Comment ]
By Per A Gustafsson, MD, PhD, et al • www.ProHealth.com • June 1, 2010


Aim: Measure efficacy of EPA in children with ADHD. [Note: EPA is eicosapentaenoic acid – an omega-3 essential fatty acid derived from oily fish or fish oil (or for nursing infants, breast milk). Physiologically it is required in high levels in the brain and is essential for optimal neuronal functioning.]

Methods: Randomized controlled trial of 0.5g EPA or placebo (15 weeks) in 92 children (7-12 years) with ADHD. Efficacy measure was Conners' Parent/Teacher Rating Scales (CPRS/CTRS).

Fatty acids were analyzed in serum phospholipids and red blood cell membranes (RBC) at baseline and endpoint with gas chromatography.

Results:

• EPA improved CTRS inattention/cognitive subscale (p = 0.04), but not Conners' total score.

• In oppositional children (n = 48) CTRS total score improved 25% or more in 48% of the children receiving EPA vs. 9% for placebo (ES 0.63, p = 0.01). [Note: oppositional children may express defiance and anger along with attention/hyperactivity problems.]

• In less hyperactive/impulsive children (n = 44), 25% or greater improvement was seen in 36% vs. 18% (ES 0.41, n.s.),

• And with both these types of symptoms 8 of 13 with EPA vs. 1 of 9 for placebo improved 25% or more (p = 0.03).

• Children responding to treatment had lower EPA concentrations (p = 0.02), higher AA/EPA (p = 0.005) and higher AA/DHA ratios (p = 0.03) in serum at baseline.

• Similarly, AA/EPA (p = 0.01), AA/DHA (p = 0.038) and total omega-6/omega-3 ratios (p = 0.028) were higher in RBC, probably due to higher AA (p = 0.011).

Conclusion:

• Two ADHD subgroups (oppositional and less hyperactive/impulsive children) improved after 15 weeks EPA treatment.

• Increasing EPA and decreasing omega-6 fatty acid concentrations in phospholipids were related to clinical improvement. [Note: plant oil-derived omega-6 fatty acids are also essential, but the average Western diet includes more than 10 times the proper amount via commercial/processed foods.]

Source: Acta Paediatrica, May 19, 2010. PMID: 20491709, by Gustafsson PA, Birberg-Thornberg U, Duchén K, Landgren M, Malmberg K, Pelling H, Strandvik B, Karlsson T. Departments of Child Psychiatry, Behavioral Sciens and Learning, and Pediatrics, Linköping University; Dept of Pediatrics, Mariestad, Dept of Child Psychiatry  Karolinska Institute,  Uppsala University ;  Dept of Pediatrics, Gothenburg University; Dept of Biosciences and Nutrition, NOVUM, Karolinska Institute, Stockholm, Sweden.  [Email: Per.A.Gustafsson@liu.se]





Join the Discussion Post a Comment 




[ Be the first to comment on this article ]




 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Save on Your Next Order

Featured Products

FibroSleep™ by ProHealth FibroSleep™ by ProHealth
The All-in-One Natural Sleep Aid
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium

Natural Remedies

Running on Empty? Fuel Up with NADH Running on Empty? Fuel Up with NADH
More Weight Loss than Any Other Discovery in Supplement History More Weight Loss than Any Other Discovery in Supplement History
The Revolutionary 'Good Fat' That Promotes Heart, Brain, Bone and Joint Health The Revolutionary 'Good Fat' That Promotes Heart, Brain, Bone and Joint Health
Three-Step Strategy to Reverse Mitochondrial Aging Three-Step Strategy to Reverse Mitochondrial Aging
Repair Damaged Mitochondria and Reduce Fatigue Up to 45% Repair Damaged Mitochondria and Reduce Fatigue Up to 45%

FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia 101
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS 101
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE
CONTACT US
PRIVACY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing