ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Meta-analysis links vitamin D deficiency with increased risk of mortality during 10.5 year median pe...

Prevent Or Reverse Diabetes: An Amazing Herbal Intervention

Exercise and Vitamin D Better Together for Heart Health

VIDEO: Essential Oils for Weight Loss

Can Valerian Root Help You Sleep Better?

Can Ginkgo Give Your Brain a Boost?

Fighting Statin-Induced Diabetes with CoQ10

Eight servings of veggies a day is clearly best for the heart

The Many Wonders of Calming Sandalwood Oil

Curcumin — A Novel Treatment Alternative for Depression

 
Print Page
Email Article

TMS treatment offers long-term benefit for majority of major depression patients – Rush University

  [ 19 votes ]   [ Discuss This Article ]
www.ProHealth.com • October 11, 2010


“After acute response to TMS, a standardized regimen of antidepressant medication maintained the acute benefit in the majority of patients over a six-month period.”

In a study to determine the durability and long-term effects of transcranial magnetic stimulation (TMS), a consortium of psychiatric researchers has found the non-invasive, non-drug therapy to be an effective, long-term treatment for major depression.

Results of the study, led by Philip G Janicak, MD, a professor at Chicago's Rush University Medical Center, were published in the October issue of Brain Stimulation.(1)

TMS therapy is a non-invasive technique (using a device about the size of a hairdryer applied externally to the scalp) that delivers highly focused magnetic field pulses to a specific portion of the brain - the left prefrontal cortex - in order to stimulate the areas of the brain linked to depression.

[Note: seemingly, the right half of the prefrontal cortex is involved in establishing negative feelings, while the left half inhibits negative feelings, and appears to be less active in depressed people.]

These pulses are of a similar intensity to the magnetic field produced during an MRI imaging scan. The repeated short bursts of magnetic energy introduced through the scalp excite neurons locally and in connected areas in the brain.

There Was Limited Info on Long-Term Benefits

TMS received clearance from the U.S. Food and Drug Administration (FDA) in October 2008. This novel treatment option is a safe and effective, acute antidepressant therapy, but there had been limited information on its long-term benefits.

“This is the only prospective, maintenance, follow-up study which assesses the durability of acute TMS benefit in patients with major depression,” said Dr. Janicak.

In the study:

• 301 patients suffering from major depression were randomly assigned to receive active or sham TMS using an FDA-approved TMS device in an acute, six-week, controlled trial. (Patients treated with TMS therapy do not require anesthesia or sedation and remain awake and alert. It is a 40-minute outpatient procedure that is prescribed by a psychiatrist and performed in an outpatient setting. The treatment is typically administered daily for four-to-six weeks.)

• Patients who responded then underwent a three-week transition period where they were tapered off of active or sham TMS treatment and started on a standard antidepressant for maintenance. After any successful acute treatment for depression such as TMS, antidepressant medications, or electroconvulsive (ECT) therapy, it is usual practice to introduce maintenance medication to lessen the chance of relapsing.

In the acute, randomized trial:

• 142 patients who received active TMS therapy responded and entered the three-week transition phase.

• 121 patients completed this phase without relapse.

• Of those patients, 99 (81.8%) then agreed to be followed for an additional 24-week period, during which only 10 patients relapsed.

In addition, TMS was successfully used as an intermittent rescue strategy to preclude impending relapse in 32 (84%) of 38 patients.

This indicated that:

• The therapeutic effects of TMS are durable in the majority of acute responders,

• And that reintroduction of TMS as an adjunct to medication was effective and safe in preventing relapse.

“The results of the follow-up study further support TMS as a viable treatment option for patients with major depression who have not responded to conventional antidepressant medications,” said Janicak.

“After acute response to TMS, a standardized regimen of antidepressant medication maintained the acute benefit in the majority of patients over a six-month period.”

One-Third Don’t Benefit from Current Antidepressants

Depression affects at least 14 million American adults each year. Researchers estimate that by the year 2020, depression will be the second leading cause of disability worldwide. About two-thirds of those who experience an episode of depression will have at least one other episode in their lives.

Depression is a debilitating illness, and existing treatment options are frequently ineffective or intolerable due to side effects. Current antidepressant therapies are not beneficial for at least a third of depressed individuals, leaving many with a lack of adequate treatment options.

___

1. "Durability of clinical benefit with transcranial magnetic stimulation (TMS in the treatment of pharmacoresistant major depression: Assessment of relapse during a 6-month, multisite, open-label study."

Source: Rush University Medical Center news release, Oct 11, 2010




Post a Comment

Featured Products From the ProHealth Store
Mitochondria Ignite™ with NT Factor® Optimized Curcumin Longvida® FibroSleep™

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
NAD+ Ignite with Niagen

Featured Products

Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils

Natural Remedies

Top 3 Nutrients to Detox the Liver and Soothe Digestion Top 3 Nutrients to Detox the Liver and Soothe Digestion
Rejuvenating the Brain - How PQQ Helps Power Up Mental Processing Rejuvenating the Brain - How PQQ Helps Power Up Mental Processing
Magnesium + Malic Acid: One-Two Punch for Pain & Fatigue Magnesium + Malic Acid: One-Two Punch for Pain & Fatigue
The Revolutionary 'Good Fat' That Promotes Heart, Brain, Bone and Joint Health The Revolutionary 'Good Fat' That Promotes Heart, Brain, Bone and Joint Health
Thyroid Health and Fibromyalgia Thyroid Health and Fibromyalgia

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map