ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Is a Good Night's Sleep at the Top of Your Wishlist?

Ashwagandha Helps Hormones - Aids Arthritis

Why You Should Be Eating More Porcini Mushrooms

A Breathalyzer for Disease?

How Bacopa Can Help Improve Your Cognitive Function

Magnesium Reduces Diabetes and Helps Keep You Young

Lavender Aromatherapy Can Ease Pre-Op Anxiety

Give Your Health a Much-Needed Boost With Geranium

The Role of Resveratrol in Achieving Optimal Health

Could Coconut Oil Help Reduce Antibiotics?

 
Print Page
Email Article

Lipid peroxidation products as potential bioindicators of Lyme arthritis - Source: European Journal of Microbiology & Infectious Diseases, Nov 6, 2010

  [ 16 votes ]   [ Discuss This Article ]
By W Luczaj, A Moniuszko, et al. • www.ProHealth.com • November 24, 2010


[Note: To read the full text of this article free, click HERE. Lipid peroxidation product levels are measures of free radical damage (oxidation) to fatty acids that form the membranes, energy-producing mitochondria, and other components of cells.]

Lipid peroxidation products, malondialdehyde (MDA), 4-hydroxynonenal (4-HNE) and [8 – isoPGF2a, a type of isoprostane], were determined in the plasma and urine of patients with Lyme arthritis and healthy people.

The group consisted of 19 patients with Lyme arthritis (mean age 47 years ) and the control group consisted of 16 healthy individuals (mean age 38 years).

Diagnosis of Lyme disease was confirmed by epidemiological anamnesis, clinical manifestation of arthritis and serological examinations.

Lipid peroxidation was estimated by the measurement of aldehydes (MDA and 4-HNE, determined by high-performance liquid chromatography [HPLC]) and prostaglandin derivatives ([8 – isoPGF2a], determined by liquid chromatography/mass spectrometry [LC/MS]).

MDA and 4-HNE levels were increased about 2- to 4-fold in the plasma, while in the urine, the increases were about 2-fold.

More significant increases were noted for the [8 – isoPGF2a] total plasma level, which was enhanced over 4-fold, and for the urine [8 – isoPGF2a] level, which was increased over 8-fold.

The [8 – isoPGF2a] total plasma level consists of free and esterified form. During infection, the ratio of free to esterified form is significantly smaller compared to healthy people.

The ratio of free to esterified form of [8 – isoPGF2a] may be a useful indicator of Lyme arthritis.

Moreover, the complementarities of three lipid peroxidation product levels may be helpful in the diagnosis of Lyme arthritis.

Source: European Journal of Microbiology & Infectious Diseases, Nov 6, 2010. PMID: 21057969, by Luczaj W, Moniuszko A, Rusak M, Pancewicz S, Zajkowska J, Skrzydlewska E. Department of Analytical Chemistry, Medical University of Bia?ystok, Bia?ystok, Poland. [Email: annamoniuszko@op.pl]





Post a Comment

Featured Products From the ProHealth Store
FibroSleep™ Energy NADH™ 12.5mg Ultra ATP+, Double Strength


Article Comments



Be the first to comment on this article!

Post a Comment


 
Optimized Curcumin Longvida with Omega-3

Featured Products

Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium

Natural Remedies

Break Free From Fibromyalgia Break Free From Fibromyalgia
The Remarkable Benefits of Reishi Medicinal Mushrooms The Remarkable Benefits of Reishi Medicinal Mushrooms
The Genetic Mutation That May Compromise Your Health - And What to Do About It The Genetic Mutation That May Compromise Your Health - And What to Do About It
IBS, Crohn’s Disease, Colitis, and Other Digestive Disorders IBS, Crohn’s Disease, Colitis, and Other Digestive Disorders
SAD? Coping with Seasonal Affective Disorder SAD? Coping with Seasonal Affective Disorder

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map