ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Astaxanthin Is a Longevity Promoter

Meta-analysis links vitamin D deficiency with increased risk of mortality during 10.5 year median pe...

Prevent Or Reverse Diabetes: An Amazing Herbal Intervention

Exercise and Vitamin D Better Together for Heart Health

VIDEO: Essential Oils for Weight Loss

Can Valerian Root Help You Sleep Better?

Eight servings of veggies a day is clearly best for the heart

The Many Wonders of Calming Sandalwood Oil

Can Ginkgo Give Your Brain a Boost?

Fighting Statin-Induced Diabetes with CoQ10

 
Print Page
Email Article

Lipid peroxidation products as potential bioindicators of Lyme arthritis - Source: European Journal of Microbiology & Infectious Diseases, Nov 6, 2010

  [ 16 votes ]   [ Discuss This Article ]
By W Luczaj, A Moniuszko, et al. • www.ProHealth.com • November 24, 2010


[Note: To read the full text of this article free, click HERE. Lipid peroxidation product levels are measures of free radical damage (oxidation) to fatty acids that form the membranes, energy-producing mitochondria, and other components of cells.]

Lipid peroxidation products, malondialdehyde (MDA), 4-hydroxynonenal (4-HNE) and [8 – isoPGF2a, a type of isoprostane], were determined in the plasma and urine of patients with Lyme arthritis and healthy people.

The group consisted of 19 patients with Lyme arthritis (mean age 47 years ) and the control group consisted of 16 healthy individuals (mean age 38 years).

Diagnosis of Lyme disease was confirmed by epidemiological anamnesis, clinical manifestation of arthritis and serological examinations.

Lipid peroxidation was estimated by the measurement of aldehydes (MDA and 4-HNE, determined by high-performance liquid chromatography [HPLC]) and prostaglandin derivatives ([8 – isoPGF2a], determined by liquid chromatography/mass spectrometry [LC/MS]).

MDA and 4-HNE levels were increased about 2- to 4-fold in the plasma, while in the urine, the increases were about 2-fold.

More significant increases were noted for the [8 – isoPGF2a] total plasma level, which was enhanced over 4-fold, and for the urine [8 – isoPGF2a] level, which was increased over 8-fold.

The [8 – isoPGF2a] total plasma level consists of free and esterified form. During infection, the ratio of free to esterified form is significantly smaller compared to healthy people.

The ratio of free to esterified form of [8 – isoPGF2a] may be a useful indicator of Lyme arthritis.

Moreover, the complementarities of three lipid peroxidation product levels may be helpful in the diagnosis of Lyme arthritis.

Source: European Journal of Microbiology & Infectious Diseases, Nov 6, 2010. PMID: 21057969, by Luczaj W, Moniuszko A, Rusak M, Pancewicz S, Zajkowska J, Skrzydlewska E. Department of Analytical Chemistry, Medical University of Bia?ystok, Bia?ystok, Poland. [Email: annamoniuszko@op.pl]





Post a Comment

Featured Products From the ProHealth Store
Vitamin D3 Extreme™ Mitochondria Ignite™ with NT Factor® Optimized Curcumin Longvida®

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
NAD+ Ignite with Niagen

Featured Products

FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium

Natural Remedies

Quercetin: Natural Support for Allergy & Inflammation Relief and More Quercetin: Natural Support for Allergy & Inflammation Relief and More
Magnesium + Malic Acid: One-Two Punch for Pain & Fatigue Magnesium + Malic Acid: One-Two Punch for Pain & Fatigue
Block Acid Reflux to Prevent Esophageal Problems! Block Acid Reflux to Prevent Esophageal Problems!
How Glutathione Can Save Your Life How Glutathione Can Save Your Life
Natural Relief for Soreness, Pain and Swelling - Putting Out the Fire Natural Relief for Soreness, Pain and Swelling - Putting Out the Fire

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map