Activate Now
 
ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Patient Insights into the Design of Technology to Support a Strengths-Based Approach to Health Care.

SURVEY: Weight Management & Chronic Illness

Japanese green tea consumers have reduced risk of dementia

Do Nothing, Accomplish Everything! The Connection Between Breathing and Healing

Meet the ProHealth Editors

Best Herbs to Help With Insomnia

Choline: Why You Should Eat Your Egg Yolks and Take Krill

Calcium, vitamin D supplementation associated improved stroke recovery

Acupressure reduced fatigue in breast cancer survivors

More positive evidence for melatonin in breast cancer battle

 
Print Page
Email Article

Rapid increase in myocardial infarction risk following diagnosis of rheumatoid arthritis amongst patients diagnosed between 1995 and 2006 – Source: Journal of Internal Medicine, Dec 2010

  [ 10 votes ]   [ Discuss This Article ]
By Mary E Holmqvist, et al. • www.ProHealth.com • December 9, 2010


Background: The risk of ischemic heart disease (IHD) [reduced blood flow/oxygen supply to the heart muscle], and in particular myocardial infarction (MI) [“heart attack”], is increased amongst patients with established rheumatoid arthritis (RA). Few studies have included contemporary patients with RA.

• We recently reported that the risk of IHD is not elevated before the onset of RA symptoms.

• However, when, in relation to RA diagnosis, the risk is increased is unknown.

Objective: To assess the risk of MI and other IHD events amongst patients diagnosed with RA during the last decade and within 18 months following RA symptom onset, compared to the general population, by time since RA diagnosis, year of RA diagnosis and by rheumatoid factor (RF) status.

Methods and patients: A Swedish inception cohort of RA (number = 7,469) diagnosed between 1995 and 2006 and a matched general population comparator cohort (number = 37,024), was identified and linked to national registers of morbidity and mortality from IHD. Relative risks (RRs) of MI and other IHD events were estimated using Cox regression.

Results:

During follow-up, 233 patients with RA and 701 controls developed a first MI, corresponding to an overall RR of MI of 1.6 (95% confidence interval 1.4, 1.9). Note: a risk ratio of 1.0 would indicate no difference in average risk. [Note: The RR of 1.6 indicates average risk in these RA patients was increased by 60%.]

Increased risks of MI were already detected within 1 to 4 years following RA diagnosis, as well as in:

• Patients diagnosed with RA during the last 5 years,

• In RF-negative patients [Note: RF (rheumatoid factor) is an antibody considered an indicator of RA not normally found in healthy people. It escalates so that it is detected via blood tests in 33% of patients at 3 months after diagnosis and in 75% at one year. As many as 20% of RA patients remain RF negative.]

• And for transmural as well as nontransmural MIs [a transmural MI affects the full thickness of the heart wall].

Conclusions:

MI risk increases rapidly following RA diagnosis, suggesting the importance of additional mechanisms other than atherosclerosis [plaque buildup in artery walls].

The elevated short-term risk is present amongst patients diagnosed in recent years, underscoring the importance of MI prevention from the time of RA diagnosis.

Source: Journal of Internal Medicine, Dec 2010;268: 578–585. Holmqvist ME, Wedren S, Jacobsson LTH, Klareskog L, Nyberg F, Rantapa-Dahlzvist S, Alfresson L, Askling J. Institute of Environmental Medicine, Karolinska Institutet, Stockholm; Karolinska Institutet/Karolinska Hospital, Stockholm; Malmö University Hospital, Malmö; AstraZeneca R&D, Mölndal; and Umea University Hospital, Umea, Sweden. [Email: marie.holmqvist@ki.se]





Post a Comment

Featured Products From the ProHealth Store
Ultra EPA  - Fish Oil FibroSleep™ Optimized Curcumin Longvida®

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
Natural Pain Relief Supplements

Featured Products

Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils

Natural Remedies

Bone Broth Benefits for Digestion, Arthritis and Cellulite Bone Broth Benefits for Digestion, Arthritis and Cellulite
Green Coffee Extract: Unique Obesity Intervention Green Coffee Extract: Unique Obesity Intervention
Three-Step Strategy to Reverse Mitochondrial Aging Three-Step Strategy to Reverse Mitochondrial Aging
Guarding Against the Dangers of Vitamin D Deficiency Guarding Against the Dangers of Vitamin D Deficiency
Can Glycine + Amino Acids Be the Secret to Deep, Rejuvenating Sleep? Can Glycine + Amino Acids Be the Secret to Deep, Rejuvenating Sleep?

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE AND SAVE 15% NOW*
Be the first to know about new products, special discounts and the latest health news. *New subscribers only

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map