ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

The Health Benefits of Manuka Honey

Increase Your Magnesium Intake

Vitamin D supplementation could ease IBS symptoms

Top Tips to Boost Your Immunity

11 Amazing Health Benefits of Using Baking Soda

Nicotinamide riboside shows promise for treatment of Alzheimer’s disease

Exercise, calcium, vitamin D, and other factors linked with fewer injurious falls

Vitamin D3 Is a Powerhouse for Your Heart

Curcumin Supplementation May Impart Long-Term Cognitive Benefits

Rhodiola — A Powerful Adaptogen That Boosts Vitality and Performance, Eases Depression and Combats B...

 
Print Page
Email Article

XMRV Just Mouse DNA Contamination? Responses Continue

  [ 57 votes ]   [ Discuss This Article ]
www.ProHealth.com • December 21, 2010


On Dec 20, the journal Retrovirology published a suite of 4 articles & a commentary(1) essentially giving the impression that studies reporting evidence of XMRV infection in ME/CFS and prostate cancer patient samples is owing to contamination by mouse DNA or RNA, and suggesting “XMRV might not be a genuine human pathogen.” The articles put some reporters into an ‘XMRV is Dead’ mode.

But not so FAST.

“What these 5 are doing to the patients is a crime against humanity,” fired back the internationally known Belgian clinician/researcher, Dr. Kenny DeMeirleir. Expect much more research to be published in the first half of 2011 that contradicts their inferences, he promised.

And as for the Whittemore Peterson Institute, which directed the first study finding evidence of XMRV infection in ME/CFS patients, "The coauthors stand by the conclusions of Lombardi et al. Nothing that has been published to date refutes our data," wrote WPI research director Dr. Judy Mikovits in a special statement (attached below).

Specifically, “You will not make an immune response to a lab contaminant,” Dr. Mikovits commented to Wall Street Journal reporter Amy Dockser-Marcus (“XMRV: Raising the Issue of Contamination”).

And as for the Canadian Broadcasting Company (CBC) headline article - "Chronic fatigue [syndrome] study tainted: Scientist" - XMRV Global Action quickly responded, describing it as "a journalistic embarrassment", itself "tainted" by "slothful" failure to conduct any "interviews which capture a balance of credible opinion on the emerging XMRV science." To see XMRV Global Action's full response with expert quotes and an invitation to use the material in blogs and letters to the media, click HERE.

__________________________________

WPI STATEMENT REGARDING RETROVIROLOGY ARTICLE

Dec 20, 2010:
The Lombardi et al.(2) and Lo et al. (3) studies were done using four different methods of detection.

They were not simply PCR experiments, as were the studies by McClure et al. and others who have recently reported their difficulties with contamination.

Experienced researchers such as Mikovits, Lombardi, Lo and their collaborators understand the limitations of PCR technology, especially the possibility of sample contamination.

As a result, we and Lo et al. conducted rigorous studies to prevent and rule out any possibility that the results reported were from contamination.

In addition to the use of PCR methodology, the Lombardi team used two other scientific techniques to determine whether, in fact, we had found new retroviruses in human blood samples.

We identified a human antibody response to a gamma retroviral infection and we demonstrated that live gamma retrovirus isolated from human blood could infect human cells in culture.

These scientific findings cannot be explained by contamination with mouse cells, mouse DNA or XMRV-related virus-contaminated human tumor cells.

No mouse cell lines and none of the human cell lines reported today by Hue et al. to contain XMRV were ever cultured in the WPI lab where our PCR experiments were performed.

Humans cannot make antibodies to viruses related to murine leukemia viruses unless they have been exposed to virus proteins.

Therefore, recent publications regarding PCR contamination do not change the conclusions of the Lombardi et al. and Lo et al. studies that concluded that patients with ME/CFS are infected with human gammaretroviruses.

We have never claimed that CFS was caused by XMRV, only that CFS patients possess antibodies to XMRV related proteins and harbor infectious XMRV, which integrates into human chromosomes and thus is a human infection of as yet unknown pathogenic potential

"The coauthors stand by the conclusions of Lombardi et al. Nothing that has been published to date refutes our data."

Judy A. Mikovits
____

1. www.retrovirology.com/articles/browse.asp?date=12-2010

2. www.prohealth.com//library/showArticle.cfm?libid=14914

3. www.prohealth.com//library/showArticle.cfm?libid=15704




Post a Comment

Featured Products From the ProHealth Store
Ultra EPA  - Fish Oil Mitochondria Ignite™ with NT Factor® Vitamin D3 Extreme™


Article Comments



Be the first to comment on this article!

Post a Comment


 
Optimized Curcumin Longvida with Omega-3

Featured Products

FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health

Natural Remedies

Aches and Pains? A Simple Solution You'll Love Aches and Pains? A Simple Solution You'll Love
When a Negative is Positive - Goodnighties Recovery Sleepwear When a Negative is Positive - Goodnighties Recovery Sleepwear
A Hard-Working Molecule that May Help Ease Pain & Brighten Mood A Hard-Working Molecule that May Help Ease Pain & Brighten Mood
Curcumin and Fish Oil: A Winning Combination for Metabolic Syndrome Curcumin and Fish Oil: A Winning Combination for Metabolic Syndrome
Eating Fat is Good... Maybe... Could Be... Sometimes Eating Fat is Good... Maybe... Could Be... Sometimes

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2018 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map