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Coenzyme Q-10: A novel therapeutic approach for Fibromyalgia? Case series with 5 patients – Source: Mitochondrion, Apr 7, 2011

  [ 26 votes ]   [ 1 Comment ]
By Mario D Cordero, et al. • • April 22, 2011

Coenzyme Q-10 (CoQ-10) is an essential electron carrier in the mitochondrial respiratory chain and a strong antioxidant.

Low CoQ-10 levels have been detected in patients with Fibromyalgia (FM).

The purpose of the present work was to assess the effect of CoQ-10 on symptoms of five patients with FM.

Patients were evaluated clinically with Visual Analogical Scale of pain (VAS), and Fibromyalgia Impact Questionnaire (FIQ).

Patients with CoQ-10 deficiency showed a statistically significant reduction of symptoms after CoQ-10 treatment during 9 months (300mg/day).

Determination of deficiency and consequent supplementation in FM may result in clinical improvement.

Further analysis involving more scientifically rigorous methodology will be required to confirm this observation.

Source: Mitochondrion, Apr 7, 2011. PMID: 21496502, by Cordero MD, Alcocer-Gómez E, de Miguel M, Cano-García FJ, Luque CM, Fernández-Riejo P, Fernández AM, Sánchez-Alcazar JA. Centro Andaluz de Biología del Desarrollo, Universidad Pablo de Olavide-CSIC; Centro de Investigación Biomédica en Red de Enfermedades Raras, ISCIII; Dpto. Citología e Histología Normal y Patológica, Facultad de Medicina, Universidad de Sevilla, Sevilla, Spain. [Email:]

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Article Comments Post a Comment

not a surprise
Posted by: Sandy10m
May 7, 2011
This isn't a surprise to those of us with fibro and ME/CFS that used Co-Q-10 with much success. Since it's an anti-oxidant and anti-inflammatory, it reduces the already super-elevated inflammation that our bodies produce for some unknown reason. By reducing the inflammation, the pain is reduced. The same thing happens for the other anti-inflammatories like fish oil and quercetin. This is also why arthritis sufferers find relief from the same supplements.
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