Coenzyme Q-10 (CoQ-10) is an essential electron carrier in the mitochondrial respiratory chain and a strong antioxidant.
Low CoQ-10 levels have been detected in patients with Fibromyalgia (FM).
The purpose of the present work was to assess the effect of CoQ-10 on symptoms of five patients with FM.
Patients were evaluated clinically with Visual Analogical Scale of pain (VAS), and Fibromyalgia Impact Questionnaire (FIQ).
Patients with CoQ-10 deficiency showed a statistically significant reduction of symptoms after CoQ-10 treatment during 9 months (300mg/day).
Determination of deficiency and consequent supplementation in FM may result in clinical improvement.
Further analysis involving more scientifically rigorous methodology will be required to confirm this observation.
Source: Mitochondrion, Apr 7, 2011. PMID: 21496502, by Cordero MD, Alcocer-Gómez E, de Miguel M, Cano-García FJ, Luque CM, Fernández-Riejo P, Fernández AM, Sánchez-Alcazar JA. Centro Andaluz de Biología del Desarrollo, Universidad Pablo de Olavide-CSIC; Centro de Investigación Biomédica en Red de Enfermedades Raras, ISCIII; Dpto. Citología e Histología Normal y Patológica, Facultad de Medicina, Universidad de Sevilla, Sevilla, Spain. [Email: firstname.lastname@example.org]