ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

15 Health Benefits of Chia Seeds, According to Science

Tangerine Oil: A Citrusy Essential Oil With Well-Rounded Uses

Magnesium Deficiency Raises Your Risk of Many Chronic Ailments

Resveratrol supplementation improves arterial stiffness in type 2 diabetics

CoQ10's Potential Capabilities for Your Health

How Can Melatonin Benefit You?

Testosterone replacement therapy associated with improved urinary, sexual function

Cloves: Boost Your Immune System the Sweet and Spicy Way

8 Chia Seed Recipes

The Many Potential Health Benefits of Curcumin

 
Print Page
Email Article

Diazinon-induced brain toxicity and protection by vitamins E plus C – Source: Toxicology and Industrial Health, May 4, 2011

  [ 21 votes ]   [ Discuss This Article ]
By N Yilmaz, et al. • www.ProHealth.com • May 13, 2011


[Note: The once-lavishly employed flea & insect killer diazenon is an example of an organophosphate that is highly toxic to the human nervous system.]

Diazinon (DI) is a widely used pesticide in agriculture, resulting in environmental deleterious effects on neural systems.

The current study was performed to investigate the effects of treatment with vitamins E plus C on brain toxicity, which is possibly induced by Diazinon.

Twenty-one male rats were divided into three groups (n = 7 per group) as follows:
1. Control group (C);
2. Diazinon-treated group (DI);
3. Diazinon + vitamins E and C-treated group (DI + Vitamins).

In order to examine lipid peroxidation [free radical destruction of lipids making up cell membranes] and antioxidant [free-radical defense] status in rats, the level of malondialdehyde (MDA), activities of two free radical scavenging enzymes superoxide dismutase (SOD), glutathione peroxidase (GSH-Px) and catalase (CAT) have been studied in brain of rat.

The results showed that:

• Treatment with diazinon induced significant (p < 0.05) increases in the level of serum malondialdehyde in rat brain. [Malondialdehyde is a marker for oxidative stress.]

• The vitamins E plus C combination reduced lipid peroxidation in rat brain. The activity of SOD level was significantly higher in DI + Vitamins group, compared to the control group.

• GSH-Px, SOD and CAT values were not significantly different in the Diazinon-treated group than in the control group.

Oxidative stress contributes to Diazinon-induced brain toxicity. Our results suggested that vitamins E plus C combination may have a protective effect on Diazinon-induced brain toxicity.

Source: Toxicology and Industrial Health, May 4, 2011. Yilmaz N, Yilmaz M, Altuntas I. Department of Biochemistry, Mustafa Kemal University Medical School and Department of Neurology, Antakya State Hospital, Hatay; Department of Biochemistry, Suleyman Demirel University Medical School, Isparta, Turkey. [Email: drniaratilgan@yahoo.com]





Post a Comment

Featured Products From the ProHealth Store
Ultra EPA  - Fish Oil Vitamin E with Mixed Tocopherols Optimized Curcumin Longvida®


Article Comments



Be the first to comment on this article!

Post a Comment


 
Optimized Curcumin Longvida with Omega-3

Featured Products

FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Vitamin E with Mixed Tocopherols Vitamin E with Mixed Tocopherols
The core antioxidant for everyday health
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Pro-C Complex™ Pro-C Complex™
Buffered Vitamin C for Enhanced Absorption

Natural Remedies

Guarding Against the Dangers of Vitamin D Deficiency Guarding Against the Dangers of Vitamin D Deficiency
Carry a Massage Therapist in Your Pocket Carry a Massage Therapist in Your Pocket
The Brain Boosting and Fatigue Fighting B-12 The Brain Boosting and Fatigue Fighting B-12
Coping When Colds or Flu Catch Up with You Coping When Colds or Flu Catch Up with You
Complete and Natural Menopause Relief Complete and Natural Menopause Relief

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map