ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

10 Fibro-Friendly Foods with a Bonus: Beautiful Skin

Studies Show that Magnesium L-threonate Improves Brain Plasticity, Leading to Direct and Significant...

Clary Sage Oil May Be Pricey, but Its Benefits Are Priceless

Pumpkin Pie Turmeric Breakfast Smoothie - Vegan + Gluten-Free

Component of red wine, grapes can help to reduce inflammation, study finds

Poly MVA: A Novel Therapy for Increasing Energy, Repairing DNA, and Promoting Overall Health

Vitamin D supplementation extends life in mouse model of Huntington's disease

Omega-3 fatty acid stops known trigger of lupus

Conquer Your Email Inbox, Increase Productivity and Reduce Stress

The Significance of Selenium

Print Page
Email Article

Acetaminophen Most Cost-Effective Treatment For Osteoarthritis Pain

  [ 56 votes ]   [ Discuss This Article ] • November 22, 2002

Research presented at the American College of Rheumatology's (ACR) Annual Scientific Meeting suggests that acetaminophen -- the medicine in the pain reliever Tylenol(R) – should be the initial therapy for the treatment of osteoarthritis (OA) pain based on cost, safety, and efficacy versus other common over-the-counter (OTC) and prescription (Rx) drugs.

"We performed a cost-effectiveness analysis of different OTC and Rx medication strategies for the treatment of OA of the knee and found that acetaminophen was most cost-effective," says lead investigator Lisa Mandl, MD, of Brigham and Women's Hospital in Boston. "While there is no one known cure for this potentially debilitating condition, acetaminophen is a very safe and effective option to help manage OA pain, without the cost and potential side effects of more expensive medications."

Clinical studies have demonstrated comparable effectiveness of acetaminophen when compared with prescription anti-inflammatory medications and some doses of celecoxib and rofecoxib. According to Dr. Mandl, this study confirms the guidelines set forth in the ACR's "Recommendations for the Medical Management of Osteoarthritis of the Hip and Knee: 2000 Update," which recommends acetaminophen as initial drug therapy for pain of osteoarthritis, the most common form of arthritis among Americans.

Modeling different therapeutic interventions using TreeAge DATA software 3.5, Dr. Mandl's team obtained data on drug efficacy, tolerance, and complications from reviews of published studies, with a particular focus on data from long-term randomized controlled clinical trials. Eight medication strategies were examined, and included combinations of non-steroidal anti-inflammatory drugs (NSAIDs), NSAIDs and misoprostol 200mg four times per day, a selective COX-2 inhibitor (celecoxib 200mg twice a day or rofecoxib 25mg a day), or acetaminophen 650mg four times per day. Costs for each therapeutic combination were derived from published databases. Outcome measures were quality-adjusted life expectancy (QALE) and incremental cost-effectiveness (C/E) ratios.

Osteoarthritis, the most common type of arthritis, affects more than 21 million Americans and is a leading cause of disability in the U.S. The condition is characterized by joint pain or stiffness, usually without inflammation. Specific risk factors for developing osteoarthritis include obesity, certain occupations where joints are repeatedly used, past injury, family history, and age. Before starting treatment with medications such as acetaminophen, nonpharmacologic treatment options should be tried first, including exercise and weight loss, which is consistent with the ACR guidelines.

Post a Comment

Featured Products From the ProHealth Store
Ultra EPA  - Fish Oil Optimized Curcumin Longvida® Energy NADH™ 12.5mg

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products

Article Comments

Be the first to comment on this article!

Post a Comment

Natural Pain Relief Supplements

Featured Products

Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength

Natural Remedies

Why Berries Offer a Rainbow of Health Benefits Why Berries Offer a Rainbow of Health Benefits
IBS, Crohn’s Disease, Colitis, and Other Digestive Disorders IBS, Crohn’s Disease, Colitis, and Other Digestive Disorders
Probiotic Mint Promotes Healthy Gums & Teeth, Freshens Breath and Whitens Teeth Probiotic Mint Promotes Healthy Gums & Teeth, Freshens Breath and Whitens Teeth
Bone Broth Benefits for Digestion, Arthritis and Cellulite Bone Broth Benefits for Digestion, Arthritis and Cellulite
Three-Step Strategy to Reverse Mitochondrial Aging Three-Step Strategy to Reverse Mitochondrial Aging

ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
Credit Card Processing
Be the first to know about new products, special discounts and the latest health news. *New subscribers only

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map