ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Fighting Heartburn and Gerd Naturally – And Safely!

Natural Bladder Control, Go Less and Live More

Vital Molecule Increases Cellular Energy and Improves Cognitive Function

Top Vitamin and Mineral Deficiencies — Are You at Risk?

Trimming the spare tire: Canola oil may cut belly fat

How Pomegranate May Protect Against Cancer

Omega Fix for Obesity: How the Right Fats Fight Fat

The Onion: Cancer Fighter and Food Preserver

Probiotics improve cognition in Alzheimer's patients

Curcumin Reverses the Cellular Damage of Chronic Stress

 
Print Page
Email Article

Acetaminophen Most Cost-Effective Treatment For Osteoarthritis Pain

  [ 56 votes ]   [ Discuss This Article ]
www.ProHealth.com • November 22, 2002


Research presented at the American College of Rheumatology's (ACR) Annual Scientific Meeting suggests that acetaminophen -- the medicine in the pain reliever Tylenol(R) – should be the initial therapy for the treatment of osteoarthritis (OA) pain based on cost, safety, and efficacy versus other common over-the-counter (OTC) and prescription (Rx) drugs.

"We performed a cost-effectiveness analysis of different OTC and Rx medication strategies for the treatment of OA of the knee and found that acetaminophen was most cost-effective," says lead investigator Lisa Mandl, MD, of Brigham and Women's Hospital in Boston. "While there is no one known cure for this potentially debilitating condition, acetaminophen is a very safe and effective option to help manage OA pain, without the cost and potential side effects of more expensive medications."

Clinical studies have demonstrated comparable effectiveness of acetaminophen when compared with prescription anti-inflammatory medications and some doses of celecoxib and rofecoxib. According to Dr. Mandl, this study confirms the guidelines set forth in the ACR's "Recommendations for the Medical Management of Osteoarthritis of the Hip and Knee: 2000 Update," which recommends acetaminophen as initial drug therapy for pain of osteoarthritis, the most common form of arthritis among Americans.

Modeling different therapeutic interventions using TreeAge DATA software 3.5, Dr. Mandl's team obtained data on drug efficacy, tolerance, and complications from reviews of published studies, with a particular focus on data from long-term randomized controlled clinical trials. Eight medication strategies were examined, and included combinations of non-steroidal anti-inflammatory drugs (NSAIDs), NSAIDs and misoprostol 200mg four times per day, a selective COX-2 inhibitor (celecoxib 200mg twice a day or rofecoxib 25mg a day), or acetaminophen 650mg four times per day. Costs for each therapeutic combination were derived from published databases. Outcome measures were quality-adjusted life expectancy (QALE) and incremental cost-effectiveness (C/E) ratios.

Osteoarthritis, the most common type of arthritis, affects more than 21 million Americans and is a leading cause of disability in the U.S. The condition is characterized by joint pain or stiffness, usually without inflammation. Specific risk factors for developing osteoarthritis include obesity, certain occupations where joints are repeatedly used, past injury, family history, and age. Before starting treatment with medications such as acetaminophen, nonpharmacologic treatment options should be tried first, including exercise and weight loss, which is consistent with the ACR guidelines.



Post a Comment

Featured Products From the ProHealth Store
Vitamin D3 Extreme™ Ultra ATP+, Double Strength Energy NADH™ 12.5mg


Article Comments



Be the first to comment on this article!

Post a Comment


 
Natural Pain Relief Supplements

Featured Products

Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength

Natural Remedies

Bone Broth Benefits for Digestion, Arthritis and Cellulite Bone Broth Benefits for Digestion, Arthritis and Cellulite
Cocoa's Polyphenol Riches - All the Health Benefits without the Sugar, Calories or Guilt Cocoa's Polyphenol Riches - All the Health Benefits without the Sugar, Calories or Guilt
D-ficient? Health Risks You Need to Know About D-ficient? Health Risks You Need to Know About
Red Yeast Rice - Natural Option for Supporting Healthy Cholesterol Red Yeast Rice - Natural Option for Supporting Healthy Cholesterol
Strengthen Cell Function with Energy-Boosting Niagen Strengthen Cell Function with Energy-Boosting Niagen

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map