ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

SURVEY RESULTS: Cognitive Impairment II

Fighting Heartburn and Gerd Naturally – And Safely!

Vital Molecule Increases Cellular Energy and Improves Cognitive Function

Top Vitamin and Mineral Deficiencies — Are You at Risk?

Trimming the spare tire: Canola oil may cut belly fat

How Pomegranate May Protect Against Cancer

Omega Fix for Obesity: How the Right Fats Fight Fat

Curcumin Reverses the Cellular Damage of Chronic Stress

Probiotics improve cognition in Alzheimer's patients

The Onion: Cancer Fighter and Food Preserver

 
Print Page
Email Article

Glucosamine associated with reduced lung cancer risk

  [ 5 votes ]   [ Discuss This Article ]
www.ProHealth.com • July 11, 2011


Long used for support of healthy cartilage and joint structure, research indicates glucosamine supports free-radical scavenging and immunostimulating activities as well.

Article:
Use of glucosamine and chondroitin and lung cancer risk in the VITamins And Lifestyle (VITAL) cohort
- Source: Cancer Causes & Control, Jun 25, 2011

By Theodore M Brasky, et al.

Objective: Inflammation plays an important role in lung carcinogenesis. Epidemiologic studies have reported inverse associations of non-steroidal anti-inflammatory drug (NSAID) use and lung cancer risk [more NSAID use, less lung cancer incidence].

Previously, we found that use of glucosamine and chondroitin, which have anti-inflammatory properties, were inversely associated with lung cancer risk.

After an additional year of follow-up, we further examined the association including frequency/duration of use, interaction with factors associated with inflammation, and lung cancer histology.

Methods: Participants were members of the VITamins And Lifestyle cohort. A study of dietary supplements and cancer risk, run by the Fred Hutchinson Cancer Research Center.] Adults, aged 50-76 years, who were residents of western Washington State, completed a baseline questionnaire in 2000-2002 (number = 76,904).

Participants were queried on their use of glucosamine and chondroitin, over the 10 years prior to baseline, and categorized as:

• Non-user,

• Low use (less than 4 days/week or less than 3 years),

• Or high use (4 days/week or more and 3 years or more).

Lung cancer cases (n = 808) were ascertained through linkage to the Surveillance, Epidemiology, and End Results cancer registry.

Results: High 10-year use of glucosamine [hazard ratio (HR), 0.77; 95% CI: 0.56-1.07; p trend = 0.04] but not chondroitin was associated with a reduction in lung cancer risk.

The association with glucosamine was limited to adenocarcinoma (HR, 0.49; 95% CI: 0.27-0.90; p trend <0.01) and was not modified by NSAID use or smoking status. [A hazard ratio of 1.00 would indicate no difference in risk between high glucosamine use group and others. An HR of 0.49 indicates risk is reduced by half, or 51% lower.]

Conclusion: Our results for glucosamine use are similar to the prior human studies of NSAID use and lung cancer, both in magnitude and the limitation of the association to adenocarcinoma.

Unlike NSAIDs, glucosamine has no known adverse effects.

Although confirmatory studies are needed, glucosamine is an attractive candidate for lung cancer chemoprevention.

Source: Cancer Causes & Control, Jun 25, 2011. PMID: 21706174, by Brasky TM, Lampe JW, Slatore CG, White E. Cancer prevention Unit, The Fred Hutchinson Cancer Research Center, Seattle Washington, USA. [Email: tbrasky@fhcrc.org]





Post a Comment

Featured Products From the ProHealth Store
Energy NADH™ 12.5mg Optimized Curcumin Longvida® Glucosamine Chondroitin Extra Strength


Article Comments



Be the first to comment on this article!

Post a Comment


 
Natural Pain Relief Supplements

Featured Products

Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Glucosamine Chondroitin Extra Strength Glucosamine Chondroitin Extra Strength
Move More Freely and Stay Healthier Longer
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium

Natural Remedies

Physically and Mentally Exhausted? How to Restore Energy at Its Source Physically and Mentally Exhausted? How to Restore Energy at Its Source
The Curcumin Revolution: 'Golden' Ticket to Better Health The Curcumin Revolution: 'Golden' Ticket to Better Health
Vitamin K-2 – A Key Player in Cardiovascular and Bone Health Vitamin K-2 – A Key Player in Cardiovascular and Bone Health
When a Good Night's Sleep Is Just a Daydream... When a Good Night's Sleep Is Just a Daydream...
Running on Empty? Fuel Up with NADH Running on Empty? Fuel Up with NADH

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map