ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Can Autoimmune Conditions be Reversed? Researchers Make a Surprising Discovery

How One Tiny Molecule Turned into One Huge Health Breakthrough

Nutrients Boost Stem Cell Function

Humans have three times more brown body fat

B12 Proven Essential for Every Cell

Soy isoflavones may benefit breast cancer patients

How B Vitamins Improve Brain Health, Cognition, Psychiatric Problems and Mood Disorders

Dietary prebiotics improve sleep, buffer impacts of stress, says study

Exercises to Help Prevent Urinary Incontinence

Higher red blood cell omega 3 levels in women linked to lower risk of mortality over 14.9 year media...

 
Print Page
Email Article

Glucosamine associated with reduced lung cancer risk

  [ 5 votes ]   [ Discuss This Article ]
www.ProHealth.com • July 11, 2011


Long used for support of healthy cartilage and joint structure, research indicates glucosamine supports free-radical scavenging and immunostimulating activities as well.

Article:
Use of glucosamine and chondroitin and lung cancer risk in the VITamins And Lifestyle (VITAL) cohort
- Source: Cancer Causes & Control, Jun 25, 2011

By Theodore M Brasky, et al.

Objective: Inflammation plays an important role in lung carcinogenesis. Epidemiologic studies have reported inverse associations of non-steroidal anti-inflammatory drug (NSAID) use and lung cancer risk [more NSAID use, less lung cancer incidence].

Previously, we found that use of glucosamine and chondroitin, which have anti-inflammatory properties, were inversely associated with lung cancer risk.

After an additional year of follow-up, we further examined the association including frequency/duration of use, interaction with factors associated with inflammation, and lung cancer histology.

Methods: Participants were members of the VITamins And Lifestyle cohort. A study of dietary supplements and cancer risk, run by the Fred Hutchinson Cancer Research Center.] Adults, aged 50-76 years, who were residents of western Washington State, completed a baseline questionnaire in 2000-2002 (number = 76,904).

Participants were queried on their use of glucosamine and chondroitin, over the 10 years prior to baseline, and categorized as:

• Non-user,

• Low use (less than 4 days/week or less than 3 years),

• Or high use (4 days/week or more and 3 years or more).

Lung cancer cases (n = 808) were ascertained through linkage to the Surveillance, Epidemiology, and End Results cancer registry.

Results: High 10-year use of glucosamine [hazard ratio (HR), 0.77; 95% CI: 0.56-1.07; p trend = 0.04] but not chondroitin was associated with a reduction in lung cancer risk.

The association with glucosamine was limited to adenocarcinoma (HR, 0.49; 95% CI: 0.27-0.90; p trend <0.01) and was not modified by NSAID use or smoking status. [A hazard ratio of 1.00 would indicate no difference in risk between high glucosamine use group and others. An HR of 0.49 indicates risk is reduced by half, or 51% lower.]

Conclusion: Our results for glucosamine use are similar to the prior human studies of NSAID use and lung cancer, both in magnitude and the limitation of the association to adenocarcinoma.

Unlike NSAIDs, glucosamine has no known adverse effects.

Although confirmatory studies are needed, glucosamine is an attractive candidate for lung cancer chemoprevention.

Source: Cancer Causes & Control, Jun 25, 2011. PMID: 21706174, by Brasky TM, Lampe JW, Slatore CG, White E. Cancer prevention Unit, The Fred Hutchinson Cancer Research Center, Seattle Washington, USA. [Email: tbrasky@fhcrc.org]





Post a Comment

Featured Products From the ProHealth Store
FibroSleep™ Energy NADH™ 12.5mg Ultra EPA  - Fish Oil

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
NAD+ Ignite with Niagen

Featured Products

Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Glucosamine Chondroitin Extra Strength Glucosamine Chondroitin Extra Strength
Move More Freely and Stay Healthier Longer
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium

Natural Remedies

The Fast-Acting Solution for Healthy Digestive Function The Fast-Acting Solution for Healthy Digestive Function
Pioneer Scientists Uncover a Revolutionary Neuroprotective Supplement for Nerve Health Pioneer Scientists Uncover a Revolutionary Neuroprotective Supplement for Nerve Health
The Surprising Benefits of Probiotics - What You Didn't Know The Surprising Benefits of Probiotics - What You Didn't Know
D-ficient? Health Risks You Need to Know About D-ficient? Health Risks You Need to Know About
How I Found My Long-Lost Energy How I Found My Long-Lost Energy

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map