ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

15 Health Benefits of Chia Seeds, According to Science

Tangerine Oil: A Citrusy Essential Oil With Well-Rounded Uses

Natural Remedies for the Prevention of Dry Eyes

Magnesium Deficiency Raises Your Risk of Many Chronic Ailments

Resveratrol supplementation improves arterial stiffness in type 2 diabetics

CoQ10's Potential Capabilities for Your Health

How Can Melatonin Benefit You?

Cloves: Boost Your Immune System the Sweet and Spicy Way

8 Chia Seed Recipes

Testosterone replacement therapy associated with improved urinary, sexual function

 
Print Page
Email Article

Omega-3 Supplementation Lowers Inflammation and Anxiety in Medical Students: A Randomized Controlled Trial – Source: Brain, Behavior, and Immunity, Jul 16, 2011

  [ 10 votes ]   [ Discuss This Article ]
By Janice K Kiecolt-Glaser, et al. • www.ProHealth.com • July 18, 2011


[Note: Even in healthy young subjects without diagnosed anxiety disorders, this trial demonstrated that higher levels of dietary omega-3 fish oil (2.5 grams a day) supported significant reduction of anxiety symptoms and the pro-inflammatory cytokines that accompany depression, stress, and many age-associated sources of death and disability. Further, the authors have noted that the medical students as a group already tended to eat foods supporting a much healthier omega-3 to omega-6 ratio than the US population overall. The researchers therefore suggest that even greater benefits might be derived from omega-3 supplementation by individuals with less healthful diets and/or anxiety, stress, and other inflammation-related disorders.]

Observational studies have linked lower omega-3 (n-3) polyunsaturated fatty acids (PUFAs) and higher omega-6 (n-6) PUFAs with inflammation and depression, but randomized controlled trial (RCT) data have been mixed.

To determine whether n-3 decreases proinflammatory cytokine production and depressive and anxiety symptoms in healthy young adults, this parallel group, placebo-controlled, double-blind 12-week RCT compared n-3 supplementation with placebo.

The participants, 68 medical students, provided serial blood samples during lower-stress periods as well as on days before an exam. The students received either n-3 (2.5 g/d, 2085 mg eicosapentaenoic acid and 348 mg docosahexanoic acid) [fish oil] or placebo capsules that mirrored the proportions of fatty acids in the typical American diet.

Compared to controls, those students who received n-3 [fish oil] showed:

• A 14% decrease in lipopolysaccharide (LPS) stimulated interleukin 6 (IL-6) production [inflammatory markers]

• And a 20% reduction in anxiety symptoms, without significant change in depressive symptoms.

Individuals differ in absorption and metabolism of n-3 PUFA supplements, as well as in adherence; accordingly, planned secondary analyses that used the plasma omega-3 to omega-6 ratio in place of treatment group showed that decreasing omega-3 to omega-6 ratios led to lower anxiety and reductions in stimulated IL-6 and tumor necrosis factor alpha (TNF-alpha)  production, as well as marginal differences in serum TNF-alpha.

These data suggest that n-3 supplementation can reduce inflammation and anxiety even among healthy young adults.

The reduction in anxiety symptoms associated with n-3 supplementation provides the first evidence that n-3 may have potential anxiolytic [anxiety-reducing] benefits for individuals without an anxiety disorder diagnosis.

ClinicalTrials.gov identifier: NCT00519779

Source: Brain, Behavior, and Immunity, online Jul 16, 2011. Kiecolt-Glaser JK, Belury MA, Andridge R, Malarkey WB, Glaser R. Institute for Behavioral Medicine Research, and Departments of Psychiatry, Internal Medicine, Molecular Virology, Immunology, and Medical Genetics, Ohio State University College of Medicine; Department of Human Nutrition, Ohio State University, Columbus, Ohio, USA. [E-mail: Janice.Kiecolt-Glaser@osumc.edu]





Post a Comment

Featured Products From the ProHealth Store
Ultra EPA  - Fish Oil Ultra ATP+, Double Strength FibroSleep™


Article Comments



Be the first to comment on this article!

Post a Comment


 
Optimized Curcumin Longvida with Omega-3

Featured Products

Arctic Select Krill Oil™ Arctic Select Krill Oil™
Your Ultimate Source of Omega-3
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium

Natural Remedies

The Big Blue Fish that Helps Chase the Blues Away The Big Blue Fish that Helps Chase the Blues Away
Running on Empty? Fuel Up with NADH Running on Empty? Fuel Up with NADH
Optimize Your Immune System Naturally: Thymic Protein A Optimize Your Immune System Naturally: Thymic Protein A
Natural Support for Mood, Sleep and Mental Focus? L-theanine Natural Support for Mood, Sleep and Mental Focus? L-theanine
When a Negative is Positive - Goodnighties Recovery Sleepwear When a Negative is Positive - Goodnighties Recovery Sleepwear

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map