ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

On-and-off fasting helps fight obesity, study finds

16 Tips from 16 Years Sick

Fibromyalgia Fare Fit for All Seasons

New Study Shows Artificial Sweeteners Lead to Diabetes

Essential Oils — An Effective and Healthy Option to Treat Headaches

Higher vitamin D levels associated with less severe disease in NAFLD patients

Can Pomegranates Slow Aging?

Krill Oil: Make This Omega-3 Supplement Part of Your Health Regimen

How zinc helps fight esophageal cancer

What Benefits Can You Get From High-Quality Whey Protein?

 
Print Page
Email Article

Chondroitin sulfate supports reduced OA hand pain & stiffness safely

  [ 9 votes ]   [ Discuss This Article ]
www.ProHealth.com • September 6, 2011


[Note: According to the authors of this large, well-controlled study, 20% to 30% of all adults have OA of the hand, rising to 50% after age 60. Little research has focused on therapies for hand OA per se, so the trial provides valuable insight regarding potential benefits of sustained nutritional supplementation for this group.]

Article:
Symptomatic effect of chondroitin sulfate 4&6 in hand osteoarthritis the finger osteoarthritis chondroitin treatment study (FACTS) – Source: Arthritis & Rheumatism, Sep 6, 2011

By Cem Gabay, et al.

Objective: To evaluate the symptomatic effect of highly purified chondroitin 4&6 sulfate (CS) in patients with hand osteoarthritis (OA). [Considered a dietary supplement in the US and a medicinal product in Europe, CS is a naturally occurring molecule that is a main component of joint cartilage.]

Methods: This investigator initiated, single-center, randomized, placebo-controlled, double-blind, clinical trial included 162 symptomatic patients with radiographic hand OA (ACR criteria).

Inclusion criteria included global:

• Spontaneous hand pain on a 0-100 mm visual analogue scale (VAS) of at least 40 mm,

• And a level of functional impairment of at least 6 on the Functional Index for Hand OA (FIHOA: 0-30 scale)

… in the most symptomatic hand.

Patients received either 800 mg CS (n=80 patients) or placebo (n= 82 patients) once daily for 6 months and were analyzed in an intent-to-treat approach.

The two primary outcomes were the change from baseline to month 6 in global spontaneous hand pain and in hand function.

Secondary outcomes were improvement in grip strength, duration of morning stiffness, acetaminophen consumption, and a global impression of efficacy.

Results:

• Decrease in global hand pain was significantly more pronounced in the CS than in the placebo group (VAS: reduced 8.7 mm, P=0.02).

Hand function improved significantly more in the CS than in the placebo group (FIHOA: reduced 2.14 points, P=0.008).

• There was a statistically significant difference between groups in favor of CS for the duration of morning stiffness and for the global impression of treatment efficacy.

• Evolution of grip strength, acetaminophen consumption, and safety endpoints were not significantly different between the two groups.

Conclusion: This study demonstrates that CS improves hand pain and function in symptomatic hand OA, with a good safety profile.

Source: Arthritis & Rheumatism, Sep 6, 2011. DOI: 10.1002/art.30574, by Gabay C, Medinger-Sadowski C, Gascon D, Kolo F, Finckh A. Divisions of Rheumatology and Radiology, University Hospitals of Geneva and University of Geneva School of Medicine, Switzerland.





Post a Comment

Featured Products From the ProHealth Store
Glucosamine, Chondroitin & MSM Optimized Curcumin Longvida® Glucosamine Chondroitin Extra Strength


Article Comments



Be the first to comment on this article!

Post a Comment


 
Optimized Curcumin Longvida with Omega-3

Featured Products

Glucosamine Chondroitin Extra Strength Glucosamine Chondroitin Extra Strength
Move More Freely and Stay Healthier Longer
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Glucosamine, Chondroitin & MSM Glucosamine, Chondroitin & MSM
Comprehensive Nutritional Joint Support

Natural Remedies

Reversing Neurodegeneration with a New Magnesium Compound Reversing Neurodegeneration with a New Magnesium Compound
SAD? Coping with Seasonal Affective Disorder SAD? Coping with Seasonal Affective Disorder
Astaxanthin - A Little-Known but Power-Packed Nutrient Astaxanthin - A Little-Known but Power-Packed Nutrient
When a Negative is Positive - Goodnighties Recovery Sleepwear When a Negative is Positive - Goodnighties Recovery Sleepwear
Natural Support for Mood, Sleep and Mental Focus? L-theanine Natural Support for Mood, Sleep and Mental Focus? L-theanine

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map