ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Inflammation Disrupts Memory - What Can You Do to Protect Your Brain?

Artificial sweeteners linked to risk of weight gain, heart disease and other health issues

All About Ginkgo Biloba: Benefits of This Timeless Herbal Supplement

Yarrow Oil: Here's Why It Deserves a Place in Your First-Aid Kit

Vitamin D supplement use associated with lower risk of breast cancer

Carnitine deficiency suggested as contributor to autism

Hop Oil: A Safe Sleep Aide

Lutein — An Important Nutrient for Eye and Brain Health

White Camphor Oil: The Purest Camphor Oil

Taurine: Facts About This Crucial Amino Acid

 
Print Page
Email Article

Nasal-spray insulin improved mild-to-moderate Alzheimer’s memory function in NIH-led trial

  [ 24 votes ]   [ Discuss This Article ]
www.ProHealth.com • September 18, 2011


Results of a pilot clinical trial show a nasal-spray form of insulin delayed memory loss and preserved cognition in people with cognitive deficits that range from mild cognitive impairment (MCI) to moderate Alzheimer’s disease.

A team led by Suzanne Craft, PhD, at the Veterans Affairs Puget Sound Health Care System in Seattle led the trial, which was sponsored in large part by the National Institute on Aging (NIA), part of the National Institutes of Health. Importantly:

• Previous research suggests that insulin abnormalities contribute to Alzheimer’s pathophysiology.

• Researchers suspected that restoring normal insulin function in the brain may provide cognitive benefit and slow disease progression.

• A nasal spray delivers insulin quickly and directly to the brain - and does not result in harmful side effects, such as increased insulin levels in the rest of the body.

The trial included 104 adults with either “amnestic MCI” - in which people have memory loss and may progress to Alzheimer’s - and those with mild to moderate Alzheimer’s disease dementia.

The trial participants received either: 20 IU (international units) of insulin; 40 IU of insulin; or a saline placebo, all administered through a nasal drug delivery device for 4 months.

Memory, cognition and functional ability were measured before and after treatment. A subset of participants also received lumbar punctures to test cerebrospinal fluid and brain scans before and after treatment.

As outlined in the researchers’ report,* published online Sep 12 by the AMA's Archives of Neurology, "Treatment with 20 IU of intranasal insulin improved memory - and both doses of insulin preserved general cognition and functional ability."

These results point out the need for larger trials of insulin nasal-spray therapy to further test its effectiveness in treating Alzheimer’s disease.

___

* Free full-text article: “Intranasal Insulin Therapy for Alzheimer Disease and Amnestic Mild Cognitive Impairment: A Pilot Clinical Trial” Craft S, et al. Archives of Neurology. Online Sep 12, 2011.

Source: National Institute on Aging news release, Sep 12, 2011




Post a Comment

Featured Products From the ProHealth Store
Energy NADH™ 12.5mg Optimized Curcumin Longvida® Ultra EPA  - Fish Oil


Article Comments



Be the first to comment on this article!

Post a Comment


 
NAD+ Ignite with Niagen

Featured Products

Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function

Natural Remedies

When a Good Night's Sleep Is Just a Daydream... When a Good Night's Sleep Is Just a Daydream...
Block food Cravings At Their Molecular Root Block food Cravings At Their Molecular Root
The Genetic Mutation That May Compromise Your Health - And What to Do About It The Genetic Mutation That May Compromise Your Health - And What to Do About It
How I Found My Long-Lost Energy How I Found My Long-Lost Energy
More Weight Loss than Any Other Discovery in Supplement History More Weight Loss than Any Other Discovery in Supplement History

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map