Activate Now
 
ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

The New Dual Activation Pain Relief Cream

SURVEY RESULTS: Medical Marijuana

Recipe: Mega-Golden Milk

Sweep Away Senile Cells

Vitamin D supplementation shows promise for Hashimoto's thyroiditis

A Paleolithic-type diet may help reduce future risk of diabetes and cardiovascular disease

Large whey protein breakfast may help manage type 2 diabetes

Decreased levels of vitamin D associated with reduced methylation in African American teens

Selenium — What Is it and Where Do I Get It?

Meta-analysis adds evidence to antidepressant effect for omega-3

 
Print Page
Email Article

Low B12 associated with faster brain & cognitive decline, Chicago Health & Aging Project reports

  [ 17 votes ]   [ Discuss This Article ]
www.ProHealth.com • September 27, 2011


“Our findings lend support for the contention that poor vitamin B12 status is a potential risk factor for brain atrophy and may contribute to cognitive impairment.”

Older adults with low blood levels of vitamin B12 markers may be more likely to have lower brain volumes and have problems with their thinking skills, according to researchers at Rush University Medical Center, Chicago.

(Aside from dietary supplements, vitamin B12 is derived from animal foods mostly – fish, meat, poultry, dairy products and eggs. Its absorption from food depends on a healthy gut, and may be limited by drugs such as acid blockers, age, and other factors.*) 

This study, published Sep 27 by the journal Neurology, tracked 121 older Chicago residents as part of the Chicago Health and Aging Project (CHAP) - a large, ongoing prospective study involving a biracial cohort of 10,000 subjects over the age of 65.

• The 121 participants had blood drawn to measure levels of vitamin B12 and B12-related markers that can indicate a B12 deficiency. The same subjects took tests measuring their memory and other cognitive skills.

• An average of four-and-a-half years later, MRI scans of the participants’ brains were taken to measure total brain volume and look for other signs of brain damage.

Having high levels of four of five markers for vitamin B12 deficiency was associated with having lower scores on the cognitive tests - and smaller total brain volume.

“Our findings definitely deserve further examination,” says clinical nutritionist and lead author Christine C. Tangney, PhD. She adds:

• “Findings from a British trial with B vitamin supplementation are also supportive of these outcomes.”

• And “It’s too early to say whether increasing vitamin B12 levels in older people through diet or supplements could prevent these problems, but it is an interesting question to explore.”

On the cognitive tests, the scores ranged from -2.18 standardized units or points to 1.42 points, with an average of 0.23. For each increase of one micromole (one millionth of a mole, or 1mM) per liter of homocysteine, which is one of the markers of B12 deficiency, the cognitive scores decreased by 0.03 points.

Dr. Tangney noted that the level of vitamin B12 itself in the blood was not associated with cognitive problems or loss in brain volume.

She said that low vitamin B12 can be difficult to detect in older people when looking only at blood levels of the vitamin. (Blood tests don’t measure the amount of B12 that is being absorbed into and utilized by the cells. And because, unlike other water-soluble vitamins, B12 is stored in the liver, kidneys and other tissues, deficiencies of B12 in the blood per se often appear slowly.*)

“Our findings lend support for the contention that poor vitamin B12 status is a potential risk factor for brain atrophy and may contribute to cognitive impairment,” Dr. Tangney concludes.

The study was supported by the National Institute on Aging.

___

Source: Rush University Medical Center news release, Sep 27, 2011

* See “Could a Common B-12 Deficiency Be Causing Your Symptoms?”  by Dr. Dana Myatt, NMD, and Mark Ziemann, RN.




Post a Comment

Featured Products From the ProHealth Store
Neuro B-12, Methylcobalamin B-12 Extreme™ Vitamin D3 Extreme™

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
20 Helpful Tips for Cleaning and Organizing When You're Chronically Ill

Featured Products

Neuro B-12, Methylcobalamin Neuro B-12, Methylcobalamin
Promote energy levels and mental sharpness
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
B-12 Extreme™ B-12 Extreme™
The Most Potent Vitamin B-12 on Earth
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health

Natural Remedies

Fight Inflammation and Promote Cognitive Health with High-OPC Grape Seed Fight Inflammation and Promote Cognitive Health with High-OPC Grape Seed
Magnesium + Malic Acid: One-Two Punch for Pain & Fatigue Magnesium + Malic Acid: One-Two Punch for Pain & Fatigue
Sunshine Vitamin Has D-lightful Health Benefits Sunshine Vitamin Has D-lightful Health Benefits
Three-Step Strategy to Reverse Mitochondrial Aging Three-Step Strategy to Reverse Mitochondrial Aging
Aching Muscles? Top 10 Nutrients to Take Back Your Life Aching Muscles? Top 10 Nutrients to Take Back Your Life

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler

· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE AND SAVE 15% NOW*
Be the first to know about new products, special discounts and the latest health news. *New subscribers only

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map