ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

|
|
|
|

Trending News

Gut Bacteria, Artificial Sweeteners and Glucose Intolerance

Reverse Mitochondrial Damage

Culprits of Autism Identified: Toxins, Gut Bacteria, Nutritional Deficiencies, and Vaccines Made wit...

Turmeric compound boosts regeneration of brain stem cells

Use of Broad-Spectrum Antibiotics Before Age 2 Associated with Obesity Risk

CoQ10: The Longevity Factor

Is Homocysteine Making You Sick?

VIDEO: Beautiful Clouds - Relaxation and Meditation

Magnesium: Widespread Deficiency with Deadly Consequences

Elevated plasma biomarkers of chronic inflammation in Gulf War illness

 
Print Page
Email Article

Warmer weather linked to cognitive difficulties in multiple sclerosis (as in ME/CFS and fibromyalgia)

  [ 5 votes ]   [ Discuss This Article ]
www.ProHealth.com • April 27, 2012


Article:
Warmer outdoor temperature is associated with worse cognitive status in multiple sclerosis
- Source: Neurology, Mar 27, 2012

By Victoria M Leavitt, et al.

[Note: Dr. Charles Shepherd, Hon Medical Adviser to the ME Association, joins Dr. David Bell and other ME/CFS & fibromyalgia specialists in noting that these illnesses share many symptoms with multiple sclerosis - and this tendency to increased cognitive difficulties in warmer weather is one of them. Regarding ME/CFS and FM, Dr. Sarah Myhill’s theory is that poor mitochondrial energy generation requires the body to conserve blood/oxygen supply to the organs, including first the skin, causing heat intolerance, and eventually other organs including cardiovascular system and brain, causing orthostatic and cognitive symptoms.]

Objective: Patients with multiple sclerosis (MS) have more clinical exacerbations and T2 lesion activity during warmer weather. [T2 lesions are the bright spots that appear on MRI images of the MS patient’s brain. Lesions are seen in MRI brain scans of ME/CFS patients also.]

The current study is the first to investigate:

• Whether outdoor temperature is related to cognitive status across patients with MS (cross-sectional analysis),

• And whether cognitive status fluctuates with changes in outdoor temperature within patients with MS (longitudinal analysis).

Methods: For the cross-sectional analysis, 40 patients with MS and 40 healthy control (HC) subjects were recruited throughout the calendar year. Cognitive status (processing speed, memory) and outdoor temperature were recorded for the day of testing.

We calculated partial correlations between cognitive status and temperature for patients with MS and HCs, controlling for demographic and disease variables.

For the longitudinal analysis, cognitive status and outdoor temperature were recorded at baseline and 6-month follow-up in a separate sample of 45 patients with MS. We calculated the partial correlation between temperature and cognitive status at follow-up, controlling for baseline temperature and cognitive status (i.e., whether temperature changes are related to cognitive changes within patients with MS).

Results: Cross-sectionally, warmer temperature was related to worse cognitive status in patients with MS (rp = ?0.45, p = 0.006), not in HCs (rp = 0.00, p = 0.984). Longitudinally, increased outdoor temperature from baseline to follow-up was related to a decline in cognitive status within patients with MS (rp = ?0.39, p = 0.010).

Conclusions:
Cognitive status in patients with MS is worse on warmer days, consistent with a previously established link between heat and lesion activity.

Our findings have implications for clinical trial planning, treatment, and lifestyle decisions. We discuss cognitive status as a potential marker of quiescent exacerbations.

Source: Neurology, Mar 27, 2012; 78-964-968. Leavitt VM, Sumowski JF, Chiaravalloti N, DeLuca J. Kessler Foundation Research Center, West Orange, New Jersey; Departments of Physical Medicine & Rehabilitation and Neurology & Neurosciences, UMDNJ–New Jersey Medical School, Newark, New Jersey, USA. [Email: vleavitt@kesslerfoundation.org]



Please Discuss This Article:   Post a Comment 



[ Be the first to comment on this article ]




 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Save on Vitamins and Supplements

Featured Products

Vitamin D3 Extreme™ by ProHealth Vitamin D3 Extreme™ by ProHealth
50,000 IU Vitamin D3 - Prescription Strength
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
FibroSleep™ by ProHealth FibroSleep™ by ProHealth
The All-in-One Natural Sleep Aid
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%

Natural Remedies

Front Line Defense Against Colds & Flu - Support for Healthy Immune System Balance Front Line Defense Against Colds & Flu - Support for Healthy Immune System Balance
Fatigue & Fibro Fog: Could You Have a B-12 Deficiency? Fatigue & Fibro Fog: Could You Have a B-12 Deficiency?
Shoo Pain, Don't Bother Me - Top 10 Nutrients to Take Back Your Life Shoo Pain, Don't Bother Me - Top 10 Nutrients to Take Back Your Life
Anti-Inflammatory Properties of Tart Cherry Anti-Inflammatory Properties of Tart Cherry
Live Longer: Groundbreaking Research on Omega-3s Live Longer: Groundbreaking Research on Omega-3s

FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia 101
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS 101
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE
CONTACT US
PRIVACY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing