ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

|
|
|
|

Trending News

Gut Bacteria, Artificial Sweeteners and Glucose Intolerance

Reverse Mitochondrial Damage

Culprits of Autism Identified: Toxins, Gut Bacteria, Nutritional Deficiencies, and Vaccines Made wit...

Turmeric compound boosts regeneration of brain stem cells

CoQ10: The Longevity Factor

Magnesium: Widespread Deficiency with Deadly Consequences

Use of Broad-Spectrum Antibiotics Before Age 2 Associated with Obesity Risk

Is Homocysteine Making You Sick?

Extending Life and Fighting Disease with Resveratrol

VIDEO: Beautiful Clouds - Relaxation and Meditation

 
Print Page
Email Article

Belgian Trial of Sodium Oxybate for Chronic Fatigue Syndrome Announced

  [ 62 votes ]   [ Discuss This Article ]
www.ProHealth.com • May 3, 2012


May 2: Belgian investigators at University Hospital, Ghent, have announced they’re preparing to enroll about 65 patients with chronic fatigue syndrome (ME/CFS) but without fibromyalgia in a placebo controlled, randomized, double blind, cross-over efficacy trial of the experimental drug sodium oxybate (Xyrem). They apparently expect to launch in June.

Sodium oxybate is a short-acting central nervous system depressant that has gained publicity for its abuse as “the date-rape drug.” It is FDA approved to prevent episodes of cataplexy (sudden episodes of muscle weakness) or narcolepsy (sudden uncontrollable episodes of sleep during day). Currently a costly drug, physicians have tried it off-label for treatment of ME/CFS sleep & fatigue, and it has shown some promise in trials for treatment of fibromyalgia insomnia, fatigue and pain; but so far with questionable promise of FDA approval for the fibromyalgia diagnosis.  

The primary outcome measure in the Belgian trial will be effect on fatigue in ME/CFS. Secondary measures, sleepiness, sleep quality, general health, and pain. The researchers suggest the findings may support a better understanding of “the enigmatic relationship between sleep and fatigue.”

According to principal investigator An Mariman, MD, both the subjects receiving sodium oxybate and the group receiving placebo (fake medication) will be treated in their home with varying amounts of medication each night over a period of weeks.

For details and inclusion/exclusion criteria, see the study’s ClinicalTrials.gov description - http://clinicaltrials.gov/ct2/show/NCT01584934.

For questions, e-mail principal investigator An Mariman, MD: An.Mariman@ugent.be



Please Discuss This Article:   Post a Comment 



[ Be the first to comment on this article ]




 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Save on Vitamins and Supplements

Featured Products

Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Vitamin D3 Extreme™ by ProHealth Vitamin D3 Extreme™ by ProHealth
50,000 IU Vitamin D3 - Prescription Strength
Optimized Curcumin Longvida® by ProHealth Optimized Curcumin Longvida® by ProHealth
Supports Cognition, Memory & Overall Health
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%

Natural Remedies

Ubiquinol - A More Advanced Form of the Energy Producing Nutrient CoQ-10 Ubiquinol - A More Advanced Form of the Energy Producing Nutrient CoQ-10
VIDEO: Healthy Eating and Fibromyalgia VIDEO: Healthy Eating and Fibromyalgia
Protect Against Sun-Induced Skin Aging From The Inside Out Protect Against Sun-Induced Skin Aging From The Inside Out
The Revolutionary 'Good Fat' That Promotes Heart, Brain, Bone and Joint Health The Revolutionary 'Good Fat' That Promotes Heart, Brain, Bone and Joint Health
"It's Not Easy Being Green" - But It Is Healthy

FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia 101
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS 101
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE
CONTACT US
PRIVACY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing