ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

SURVEY: Cognitive Impairment II

Top 3 Nutrients to Detox the Liver and Soothe Digestion

Natural Bladder Control, Go Less and Live More

Top Vitamin and Mineral Deficiencies — Are You at Risk?

Vital Molecule Increases Cellular Energy and Improves Cognitive Function

Omega Fix for Obesity: How the Right Fats Fight Fat

Potential of Quercetin in the Treatment of Melanoma

How Pomegranate May Protect Against Cancer

Trimming the spare tire: Canola oil may cut belly fat

Supplementation with vitamins C and E associated with decreased risk of cognitive impairment, dement...

 
Print Page
Email Article

Shortness of Breath in ME/CFS May be Due to CNS Dysregulation

  [ 5 votes ]   [ Discuss This Article ]
www.ProHealth.com • March 5, 2013


Editor’s Comment: This study used the CDC “Fukuda” criteria to establish the two CFS cohorts. Although the Fukuda criteria do not require post-exertional malaise, the researchers found a positive correlation between shortness of breath (dyspnea), and “Exertional Exhaustion.” There was also a high occurrence of fibromyalgia (42% and 47%) in the two CFS groups. In the full study the authors suggest that the sensations of dyspnea, including lightheadedness and chest pain, may be due to central nervous system dysregulation, specifically, dysautonomia

Dyspnea in Chronic Fatigue Syndrome (CFS): Comparison of Two Prospective Cross-sectional Studies

~Source: Global Journal of Health Science; Vol. 5, No. 2; 2013

By Murugan Ravindran et al. 

Abstract

Background: Chronic Fatigue Syndrome (CFS) subjects have many systemic complaints including shortness of breath. Dyspnea was compared in two CFS and control cohorts to characterize potential pathophysiological mechanisms.

Methods: Cohort 1 of 257 CFS and 456 control subjects were compared using the Medical Research Council chronic Dyspnea Scale (MRC Score; range 0–5). Cohort 2 of 106 CFS and 90 controls answered a Dyspnea Severity Score (range 0–20) adapted from the MRC Score. Subsets of both cohorts completed CFS Severity Scores, fatigue, quality of life, and systemic complaints questionnaires. Cohort 2 also responded to other Dyspnea, affective and anxiety instruments. A subset had pulmonary function and total lung capacity (TLC) measurements.

Results: MRC Scores were equivalent for females and males in Cohort 1 CFS (1.92 [1.72-2.16]; mean [95% confidence interval]) and controls (0.31 [0.23-0.39]; P < 0.0001 by 2-tailed, unpaired Student's t tests with Bonferroni corrections). Receiver-operator curves identified 2 as the threshold for positive MRC Scores in Cohort 1. This indicated 54% of CFS, but only 3% of controls, had significant Dyspnea. In Cohort 2, the threshold Dyspnea Severity Score of 4 indicated shortness of breath in 67% of CFS and 23% of these controls. Cohort 2 Dyspnea Scores were higher for CFS (7.80 [6.60-9.00]) than controls (2.40 [1.60-3.20]; P < 0.0001). CFS had significantly worse fatigue, other CFS defining criteria and quality of life compared to controls. Although CFS had worse depressive affect and anxiety scores, only the controls showed correlations with Dyspnea Score. Pulmonary function was normal in CFS, but Borg scores and sensations of chest pain and dizziness were significantly greater during testing than controls. TLC was normal except for 2 of 16 CFS who had hyperinflation. A general linear model of Cohort 2 CFS responses linked Dyspnea Scores with rapid heart rate, chest pain and dizziness.

Conclusions: Sensory hypersensitivity without airflow limitation contributed to Dyspnea in CFS. Correlates of Dyspnea in controls were distinct from CFS suggesting different mechanisms.

Source: Global Journal of Health Science; Vol. 5, No. 2; 2013. Murugan Ravindran, Oluwatoyin Adewuyi, Yin Zheng, Uyenphuong Le, Christian Timbol, Samantha Merck, Rania Esteitie, Michelle Cooney, Charles Read, James Baraniuk. Georgetown University, Washington DC, USA

The full article can be accessed HERE.





Post a Comment

Featured Products From the ProHealth Store
Ultra EPA  - Fish Oil Energy NADH™ 12.5mg Ultra ATP+, Double Strength


Article Comments



Be the first to comment on this article!

Post a Comment


 
Natural Pain Relief Supplements

Featured Products

Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium

Natural Remedies

Secret Nutrient for Radiant Skin Secret Nutrient for Radiant Skin
Vital Molecule Increases Cellular Energy and Improves Cognitive Function Vital Molecule Increases Cellular Energy and Improves Cognitive Function
Front Line Defense Against Colds & Flu - Support for Healthy Immune System Balance Front Line Defense Against Colds & Flu - Support for Healthy Immune System Balance
Vitamin K-2 – A Key Player in Cardiovascular and Bone Health Vitamin K-2 – A Key Player in Cardiovascular and Bone Health
The Crucial Role CoQ10 Plays in Fibromyalgia and ME/CFS The Crucial Role CoQ10 Plays in Fibromyalgia and ME/CFS

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map