ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Is Magnesium the Missing Link in Your Heart Healthy Routine?

More evidence for calorie restriction’s longevity effect

A Little Zinc Goes a Long Way

Supplementation with vitamin D associated with improved testosterone, erectile function among middle...

Vitamin D deficiency increases risk of chronic headache

VIDEO: The Best Brain Foods That Help Increase Your Memory!

Get the Most From Your Green Tea

Iron (And More) For Lasting, Natural Energy

Metabolic syndrome increases the need for vitamin E

Supplement combo improves bone density, mood, in postmenopausal women

 
Print Page
Email Article

Exercise Shown to Have Positive Effect On Cholesterol

  [ 38 votes ]   [ Discuss This Article ]
www.ProHealth.com • November 6, 2002


For the first time, Duke University Medical Center researchers have demonstrated that exercise -- without accompanying weight loss -- has a positive impact on improving cholesterol levels.

Furthermore, they report that it is the amount of activity, and not necessarily any changes in fitness or intensity of exercise, that is important for cholesterol improvement. In the process of their studies, the Duke researchers also demonstrated that the standard lipid panels used by doctors to measure the so-called "bad" LDL and "good" HDL forms of cholesterol do not necessarily provide the most accurate information in determining one?s risk of developing heart disease.

The results of the Duke study, published today (Nov. 7, 2002) in the New England Journal of Medicine, show that exercise has a positive effect on the number and size of the particles that carry cholesterol through the bloodstream.

Cholesterol is an energy-rich fat, or lipid, that must "attach" to protein particles in order to circulate throughout the bloodstream and nourish tissues. This combined cholesterol-protein unit is known as a lipoprotein, and abnormal levels of these lipoproteins have been linked to the progression of atherosclerosis and heart disease.

"It appears from our study that cholesterol carried by smaller, denser protein particles appear to cause cardiovascular disease more efficiently than cholesterol carried by large, fluffy particles," said Duke cardiologist William Kraus, M.D., who led the study.

"We showed that increasing amounts of exercise increased the size of the particles carrying both the good and the bad cholesterol," Kraus continued. "By using new methods of measuring the particles carrying cholesterol, we found that some exercise is better than no exercise, and conversely, those patients in the control group who did not exercise actually showed worsening cholesterol levels."

According to Kraus, past studies of exercise?s effects on cholesterol have been unable to find a link because the measurements were based on the standard lipid levels as opposed to the actual cholesterol-carrying particles.

"This study had to be done because there was very little scientific information indicating whether or not exercise training would have beneficial effects on cholesterol when conducted in a state-of-the art, randomized fashion, comparing individuals who exercised to those who did not," Kraus said.

For example, exercise guidelines issued recently by the Centers for Disease Control and Prevention and the National Academy of Science are based more on expert opinion and consensus than data gained from controlled clinical studies, Kraus said.

The study, which is still studying patients, was funded by a $4.3 million grant from the National Heart, Lung and Blood Institute. One-third of the patients in the study were enrolled at East Carolina University (ECU), with the rest enrolled at Duke. Joseph Houmard, Ph.D., led the ECU portion of the study.

The results are based on the analysis of blood cholesterol changes in 84 sedentary overweight men and women with elevated lipid levels who were randomized to one of three different exercise groups: high-amount/vigorous intensity (the caloric equivalent of 20 miles of jogging per week); low-amount/vigorous intensity (equivalent of jogging 12 miles per week); and low-amount/moderate intensity (equivalent of walking briskly for 12 miles per week). Importantly, Kraus said, the group included significant numbers of African-Americans, as well as equal numbers of men and women.

"While several studies have shown that low intensity exercise can improve lipoproteins, the data from this study, taken together with other research, suggests that if there is an exercise intensity effects on lipids, it is small compared to the much clearer role that the amount of exercise plays," Kraus said.

In order to determine the role of exercise alone, participants were not allowed to change their diet during the course of the study. Each participant followed a two- to three-month "ramp-up" exercise period, followed by six months of exercise, which was carried out on cycle ergometers, treadmills or elliptical trainers in a supervised setting.

Throughout the course of the study, researchers took blood samples from participants, and then used two new and different methods to determine the subtle and specific changes in cholesterol particle size and number.

While Kraus, an ardent proponent of the benefits of exercise, believed that it would have a beneficial effect on cholesterol, he was most surprised by what appeared to happen to the control group that did not exercise during the course of the study.

"We were actually surprised that the individuals who did not exercise deteriorated as rapidly as they did in measurements of blood cholesterol, weight gain and overall health," he said. "This is characteristic of what is happening to the American population. So if we can get these people exercising, perhaps we can prevent bad things from happening."

Kraus believes that during the next 10 years, physicians will gradually move away from using the standard lipid profile tests and begin to look more closely at particle size to determine their patients' risk for heart disease. According to Kraus, inactivity ranks closely behind smoking as the greatest risk factor for heart disease, and like smoking cessation, exercise is a lifestyle modification proven to protect the heart.

"Exercise can be a very powerful way of reducing risk, not only by improving lipids as our study has shown, but also by having a positive effect on glucose levels and mood modification," he said. "We should understand that patients do not need to lose weight or focus so much on the scale, but they do need to exercise to decrease their risk of heart disease."

Joining Kraus in the study were, from Duke, Cris Slentz, Ph.D., Brian Duscha, Kenneth Knetzger, Connie Bales, Ph.D., Sarah Henes and Gregory Samsa, Ph.D. From ECU, other team members were Michelle Wharton and Jennifer McCartney.

James Otvos, Ph.D., from LipoScience, Inc., Cary, N.C., and Krishnaji Kulkarni, Ph.D., from Atherotech, Inc., Birmingham, Ala., were also members of the team. LipoScience and Atherotech developed the two different technologies for analyzing the blood samples. Kraus has no financial interest in either company.



Post a Comment

Featured Products From the ProHealth Store
Vitamin D3 Extreme™ FibroSleep™ Mitochondria Ignite™ with NT Factor®

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
NAD+ Ignite with Niagen

Featured Products

Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%

Natural Remedies

Aching Muscles? Top 10 Nutrients to Take Back Your Life Aching Muscles? Top 10 Nutrients to Take Back Your Life
Vitamin K-2 – A Key Player in Cardiovascular and Bone Health Vitamin K-2 – A Key Player in Cardiovascular and Bone Health
Everything You Always Wanted to Know About Sleep But Were Too Tired to Ask Everything You Always Wanted to Know About Sleep But Were Too Tired to Ask
The Big Blue Fish that Helps Chase the Blues Away The Big Blue Fish that Helps Chase the Blues Away
The Guaifenesin Story: A centuries-old bark extract used for clearing the airways – now key to a popular FM symptom-reversal protocol The Guaifenesin Story: A centuries-old bark extract used for clearing the airways – now key to a popular FM symptom-reversal protocol

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map