ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

|
|
|
|

Trending News

Guarding Against the Dangers of Vitamin D Deficiency

Omega-3 fatty acids, vitamin D may control brain serotonin, affecting behavior and psychiatric disor...

Fatigue & Fibro Fog: Could You Have a B-12 Deficiency?

How Glutathione Can Save Your Life

New Dietary Guidelines Reverse Flawed Recommendations on Cholesterol

Long term antibiotic therapy may be an effective treatment for children co-morbid with Lyme disease ...

Anticancer Properties Of Saffron

Beyond Depression... SAMe Broad-Spectrum Protection Against Disorders Of Aging

BPA exposure linked to autism spectrum disorder, study reports

Omega-3 Fatty Acids Appear to Protect Damaged Heart After Heart Attack

 
Print Page
Email Article

Use of isoflavone supplements is associated with reduced postmenopausal breast cancer risk

  [ 1 vote ]   [ 1 Comment ]
By B.A. Boucher et al.. • www.ProHealth.com • August 11, 2013


Editor's Note: Isoflavones are organic compounds, commonly found in soy. Because these compounds may contain phytoestrogens (plant-based hormones), they have been extensively researched for possible effects on breast cancer. While some studies have found that isoflavones have no effect on the incidence of breast cancer, others have shown a decrease of up to 35% in populations which regularly consume isoflavones. This study found a significnt reduction in post-meopausal cancer risk among women taking isoflavone supplements.

By B.A. Boucher et al..

Abstract

Botanical supplements are widely used and contain diverse ingredients, including isoflavones. Food-based isoflavones have been associated with reduced breast cancer risk. However, no study has comprehensively evaluated supplements identified by isoflavone content and breast cancer risk.

Associations between ever use of 28 isoflavone supplements and breast cancer risk in Ontario, Canada were evaluated using cases (n = 3,101) identified in 2002-2003 from the Ontario Cancer Registry and controls (n = 3,471) identified through random digit dialing methods. Multivariate logistic regression was used to estimate age-adjusted odds ratio (AOR) and 95% confidence intervals (CI).

Several individual supplements were associated with reduced breast cancer risk (e.g., Natural HRT; AOR = 0.39; 95% CI: 0.22, 0.69; n(users) = 58). Use of any isoflavone supplements was associated with reduced risk when 3 or more were ever used (AOR = 0.68; 95% CI: 0.54, 0.86; n(users) = 332; p(trend) = 0.008) or any was taken >5 years (AOR = 0.75; 95% CI: 0.60, 0.94; n(users) = 325; p(trend) = 0.01); high content supplements were consistently associated with reduced risk. Risk reduction was confined to postmenopausal breast cancer for both individual and combined supplements, and was strongest in the latter among high content users who ever took 3 or more supplements (AOR = 0.55; 95% CI: 0.38, 0.81; n(users) = 118; p(trend) = 0.04) or any >5 years (AOR = 0.47; 95% CI: 0.27, 0.81; n(users) = 60; p(trend) = 0.03). Associations did not differ by estrogen-progesterone tumor receptor status.

In conclusion, isoflavone supplements were associated with decreased postmenopausal breast cancer risk. Further research to examine these novel findings is warranted, given the low supplement use and potential limitations of our results.

Source: Int J Cancer. 2013 Mar 15;132(6):1439-50. doi: 10.1002/ijc.27769. Epub 2012 Sep 18. Boucher BA, Cotterchio M, Anderson LN, Kreiger N, Kirsh VA, Thompson LU. Prevention and Cancer Control, Cancer Care Ontario, Toronto, ON, Canada. beatrice.boucher@cancercare.on.ca




Please Discuss This Article:   Post a Comment 

Breast cancer & soy/isoflavones
Posted by: reginakay
Aug 12, 2013
Please be careful in your research. Soy/isoflavones/hormones are the LAST thing the majority of women with breast cancer need. Breast cancer is usually hormone receptor positive (75-80%) and these compounds actually feed the cancer.
Reply Reply
 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Save on Vitamins and Supplements

Featured Products

Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Optimized Curcumin Longvida® by ProHealth Optimized Curcumin Longvida® by ProHealth
Supports Cognition, Memory & Overall Health
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
FibroSleep™ by ProHealth FibroSleep™ by ProHealth
The All-in-One Natural Sleep Aid
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium

Natural Remedies

Quercetin: Natural Support for Allergy & Inflammation Relief and More Quercetin: Natural Support for Allergy & Inflammation Relief and More
Energy Breakthrough - One Fibromyalgia Patient’s Fortuitous Discovery Energy Breakthrough - One Fibromyalgia Patient’s Fortuitous Discovery
Herbal Inflammation Management for Whole Body Health Herbal Inflammation Management for Whole Body Health
How to Jump-start and Sustain Energy Production in CFS How to Jump-start and Sustain Energy Production in CFS
CoQ10's Role in Fibromyalgia and ME/CFS

FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia Diagnosis
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS Diagnosis
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE  |  PRIVACY
CONTACT US
LIBRARY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing