ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

10 Fibro-Friendly Foods with a Bonus: Beautiful Skin

Fight Back! Win the War Being Waged Against Your Immune System

Studies Show that Magnesium L-threonate Improves Brain Plasticity, Leading to Direct and Significant...

Clary Sage Oil May Be Pricey, but Its Benefits Are Priceless

Component of red wine, grapes can help to reduce inflammation, study finds

Poly MVA: A Novel Therapy for Increasing Energy, Repairing DNA, and Promoting Overall Health

Pumpkin Pie Turmeric Breakfast Smoothie - Vegan + Gluten-Free

Vitamin D supplementation extends life in mouse model of Huntington's disease

What’s Fenugreek Good For?

Omega-3 fatty acid stops known trigger of lupus

Print Page
Email Article

T cell clones shrink melanoma tumors

  [ 15 votes ]   [ Discuss This Article ] • November 13, 2002

Paper published in the Proceeding of the National Academy of Sciences
Below is an advisory distributed today by the Proceedings of the National Academy of Sciences (PNAS). The paper can be found in the online early edition of PNAS at

The study, conducted by Dr. Cassian Yee, a researcher at the Fred Hutchinson Cancer Research Center, involved 10 people diagnosed with advanced melanoma. For each patient immune system cells able to identify and target melanoma were extracted and cloned. The cloned cells were expanded in the lab and re-injected into the patient. The results of the study showed that in five patients tumors stopped growing for up to one year and in three of the patients the tumors appeared to shrink.

"While we did not expect to cure the cancers, the technique appears to benefit patients by curbing the spread of their tumors, says Dr. Yee."

Soldier Clones: T Cells Target Tumors

A preliminary clinical trial suggests that armies of T cells generated in the lab can be injected into patients to halt the spread of cancerous tumors. One strategy for treating cancer is to sensitize the immune system to the presence of tumors so it can attack the cancerous cells. Vaccinating patients with proteins present on the cancerous cells could kick the immune system into action.

Instead of relying on the immune system to manufacture a defense, however, Cassian Yee and colleagues tried supplying ready-made soldiers. In the lab, the authors grew T cells, those cells that destroy invaders or aberrant cells. To insure that the T cells found their target, the authors trained them on their quarry, stimulating the cells with a protein found on metastatic melanoma cells.

The authors then injected these designer T cells into 10 patients over the course of 12 weeks. The results, reported in article #6000, indicate that the T cells clones were able to home in on the tumors, which regressed slightly or stabilized in 8 of the 10 patients, for an average period of 11 months. In addition to T cells, the injections contained IL-2, a chemical that stimulates the T cells to replicate, resupplying the troops. Although IL-2 can be toxic in high doses, the patients showed little reaction to the low dose of IL-2 used.

Post a Comment

Featured Products From the ProHealth Store
Vitamin D3 Extreme™ FibroSleep™ Energy NADH™ 12.5mg

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products

Article Comments

Be the first to comment on this article!

Post a Comment

Natural Pain Relief Supplements

Featured Products

Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid

Natural Remedies

Nutrients to Combat the Modern Stress Epidemic Nutrients to Combat the Modern Stress Epidemic
Green Coffee Extract: Unique Obesity Intervention Green Coffee Extract: Unique Obesity Intervention
The Curcumin Revolution: 'Golden' Ticket to Better Health The Curcumin Revolution: 'Golden' Ticket to Better Health
Anti-Inflammatory Properties of Tart Cherry Anti-Inflammatory Properties of Tart Cherry
Soothe, Heal and Regulate Your Digestive System with Nutrient-Rich Aloe Vera Soothe, Heal and Regulate Your Digestive System with Nutrient-Rich Aloe Vera

ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
Credit Card Processing
Be the first to know about new products, special discounts and the latest health news. *New subscribers only

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map