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Treatment-Resistant Woman with Fibromyalgia Experiences Marked Improvement with Dextroamphetamine

  [ 22 votes ]   [ 5 Comments ]
www.ProHealth.com • April 10, 2014


Editor's comment: Dextroamphetamine is a central nervous system stimulate. “Uppers” is a colloquial term often used to describe this class of drugs. It is labeled as having high abuse potential and dependency. Dextroamphetamine has been FDA approved for the treatment of ADHD, narcolepsy and obesity. Although this patient experienced significant improvement, it's important to keep in mind that this is a case study of just one patient so we can't draw conclusions for other FM patients without more extensive studies.

Marked improvement of pain from long-term fibromyalgia with dextroamphetamine sulfate in a woman who failed to improve with conventional pharmacologic treatment.

By J.H. Check and R. Cohen

Abstract:

PURPOSE: To determine if treatment with the sympathomimetic amine dextroamphetamine sulfate, which has been so effective in treating a variety of pain syndromes, including severe pelvic pain and interstitial cystitis in women with the sympathetic neural hyperalgesia edema syndrome would also mitigate pain from fibromyalgia which was resistant to multiple therapies.

MATERIALS AND METHODS: Dextroamphetamine sulfate extended release capsules once daily was gradually increased to 25 mg per day in a woman with treatment resistant fibromyalgia of 20 years duration.

RESULTS: Within a short time, the woman experienced dramatic relief of pain. Furthermore, her edema improved resulting in a 27 pound weight loss and her chronic fatigue improved.

CONCLUSIONS: Fibromyalgia can be effectively treated with an innocuous dose of dextroamphetamine sulfate.

Source: Clinical and Experimental Obstetrics and Gynecology, 2014. By J.H. Check and R. Cohen.





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Article Comments Post a Comment

Treatment-Resistant fibromyalgia
Posted by: IanH
Apr 10, 2014
In my experience most cases of fibromyalgia ARE treatment-resistant. However it is interesting that we are seeing another case of stimulant responsive FM.
Reply Reply

Stimulans fibromyalgia sxs
Posted by: sdi
May 7, 2014
Stimulant medication has significantly improved my fibro sxs. ADD (inattentive type) was diagnosed after my fibro dx and has changed my life in many positive ways. I am sure I have always had ADD. My hope is for more research to address the strong association between attention deficit disorders and fibromyalgia. My experience of talking with many fibro patients in the past 9 years as a Disease Mgt registered nurse has been apparent to me that many patients likely would also fit in the spectrum of ADD or ADHD. I was in my 50's when I was diagnosed. The work that Nadeau and Quinn have done for girls and women with attention deficit problems is huge. Their chapter on Fibromyalgia in "Understanding Women with AD/HD" gave me the information I needed to successfully live and work well with fibromyalgia and ADD. I am so anxious to see the medical community embrace this association and offer the appropriate treatment and help for all those who need it.Thank you so much for your article.
Reply Reply

Stimulants and fibromyalgia sxs
Posted by: sdi
May 7, 2014
Stimulant medication has significantly improved my fibro sxs. ADD (inattentive type) was diagnosed after my fibro dx and has changed my life in many positive ways. I am sure I have always had ADD. My hope is for more research to address the strong association between attention deficit disorders and fibromyalgia. My experience of talking with many fibro patients in the past 9 years as a Disease Mgt registered nurse has been apparent to me that many patients likely would also fit in the spectrum of ADD or ADHD. I was in my 50's when I was diagnosed. The work that Nadeau and Quinn have done for girls and women with attention deficit problems is huge. Their chapter on Fibromyalgia in "Understanding Women with AD/HD" gave me the information I needed to successfully live and work well with fibromyalgia and ADD. I am so anxious to see the medical community embrace this association and offer the appropriate treatment and help for all those who need it.Thank you so much for your article.
Reply Reply

Vyvanse for Fibromyalgia
Posted by: juliesaunders
Oct 19, 2014
Finally! a site that acknowledges the positive effects of dextroamphetamine on Fibromyalgia. I have been searching for months. I had been disabled by symptoms of FM, Chronic Fatigue Syndrome, ADD (brain fog), Irritable bowel, bipolar, myoclonis, wakefulness during night, etc. All seem to be coming from some sort of an Autonomic Nervous System Dysfunction. I was literally bedridden six months ago. I couldn't read or write any more and was pretty much out of ideas as to how to cope without going on some crazy strong pain killers. Thankfully I didn't. Instead, I asked to try Vyvanse to help with the CFS and pain. I couldn't believe it when all my symptoms were immediately improved and continued to improve in past months. Even my eyesight has improved. Anyone else that has had this much improvement, could you please reply? I have been searching endlessly on the internet for anyone else that has had the same miraculous results as myself. Thank you.
Reply Reply

Beyond mind over matter- Fibromyalgia is real & ADD/ADHD meds improve quality of life
Posted by: Jk2Jkwith2
Apr 25, 2015
I have always been an active person and on the move. I am now 31 and I have noticed over the years that certain trauma accidents have 'caught up' with me...but due to certain medication I am properly prescribed help to continue and maintain my ability to enjoy life and maintain active and keep up with my children. Yes, I believe I am at a young age of 31 but sadly I know there are both even younger and older individuals who suffer due to not having medical help or even not proper medical help. I'm not a doctor or scientist or in the field of psychology. I am an everyday person who has already experienced plenty of knowledge with pain, sadness, uncertainty, accident trauma, countless attempts to defeat medical prescription need and trial & error attempts. I am a firm believer in mental health and toughness but the truth is sometimes,with us simply being human- that is not enough. Medical individuals and medications are indeed in existence for a purpose. If you are not understanding of why individuals, like me and millions of others truly need and benefit from medical intervention....well you are Blessed and I commend you as you have not suffered any long-lasting, near debilitating and life altering accidents/situations to cause you several areas of suffering which is not just physical. My mother (who is still amazing & strong-willed) was a hard working, strong, supportive and wonderful single-parent for certain reasons so my school issues were not due to her slacking whatsoever. During my early school years I had a speech impediment as I spoke too fast and was rambling words together then with therapy I basically overcame it but still had trouble in later school years with several issues with not slowing down on school work, not finishing or forgetting school work, easily discouraged with work I didn't understand and would do the minimum to pass, attitude and anger issues too but with certain school challenges and subjects I enjoyed or really was interested in, I exceeded...hence the ADD/ADHD diagnosis (it's a true disorder too) but I never took the medication.
My mother eventually dated and met someone when I was 11 who became my dad, they married when I was 13 and he chose to raise me as his own and is also an amazing parent but years later in my last 2 years of high school my parents began to separate and my senior year they divorced. Still did not take medication but with depression, feelings of loss and anxiety is what I dealt with and eventually I was taking Prozac in 2002 and it was not for me. My parents are divorced, I still to this day, have a great relationship with them.
Now, where I feel the beginning of my fibromyalgia may have physically resulted from was on March 1, 2002 as I was in a terrible car accident which I thought I walked away (amazingly) with just cuts & bruises....but a little more than a year later I started hurting in my neck and mid-back. After a while of trying new exercises and dietary supplements and even doing my best to out - think the pain, I had went to a chiropractor and had x-rays which showed whiplash and mid-back vertebrae re-alignment. This was from my car accident. I maintained an active and healthy lifestyle, dealt with minor aches and pain and eventually gave birth to my son. When my son was 6 yrs old (5 yrs ago) he and I had a Segway accident at a family cook out. He was fine but I landed on my low - back first (coccyx) and was unable to get up or walk for 30 minutes and then it took 3 days for me to finally start walking comfortably on my own. I didn't go to doctor as I was able to get up eventually without severe pain plus I didn't want to sit and wait. I decided to go to chiropractor here and there and just take Ibuprofen or Tylenol as needed. Over the next couple years I noticed that I was becoming very tired even after sleeping all night, I started hurting throughout my body in areas I hadn't hurt, loosing interest in previous things I enjoyed, depression and eventually my work habits were changing as I was becoming late due to not able to get up as quickly or too tired, lost motivation- this was not good. I enjoyed my job but I decided to take on a new career. I was with new employment for 2 months when I was close to termination as I was still having problems with multi-tasking and not finishing, I was exhausted and aching, becoming forgetful and a month later my spouse and I found out we were having another child. The previous issues were present but I assumed this time with new job it was pregnancy related. As I began prenatal care,overtime I told the doctor about my issues and she said that she recommended Lexapro. No, I didn't feel it was safe to take while pregnant and I eventually left that job as I felt it was best. I handled the issues as best as I could and only took prenatal vitamins and healthier eating habits. I gave birth to a healthy daughter and went back to work part-time. But, sadly the issues were still present and intensifying. I finally 'gave in' and started research on local doctor's and their practice. I found a doctor around 3 years ago who listened to my life story, asked questions, medical history etc..and he prescribed me Vyvanse. After a month or shorter I FELT the improvement both mentally and physically. My co-workers and family noticed as well. I continued to have some fatigue and minor aches throughout so my doctor also prescribed a low-down of dextroamphetamine to take as needed in the early afternoon to assist with remaining symptoms. It has helped me gain back my life and stay motivated and on-task beyond work. The connection of the Central Nervous System and fibromyalgia has to be researched to help eventually defeat fibromyalgia. My whiplash and back trauma issues have had to of disrupted my CNS as these prescriptions help by 'turning off' the pain and fatigue or just simply eliminating the tiredness and soreness I have when taking them. If only there was a permanent correction or surgery to reduce the need of medication. My current job is very physical as I am a Pick Up & Delivery Driver where I easily lift 1500 lbs throughout the day. I still maintain chiropractor care in hopes that in due time I can have my body back in alignment, my pain and aches to back off and no longer wake up needing my 'Limitless' medication every day. I am a sincere advocate for ADD/ADHD medication to help bring back the quality of life in those with fibromyalgia as well.
Thank you for reading and I hope my personal experience can help anyone to understand more about a controversial disorder and/or even to not feel alone.
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