ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

15 Health Benefits of Chia Seeds, According to Science

Tangerine Oil: A Citrusy Essential Oil With Well-Rounded Uses

Magnesium Deficiency Raises Your Risk of Many Chronic Ailments

CoQ10's Potential Capabilities for Your Health

Testosterone replacement therapy associated with improved urinary, sexual function

How Can Melatonin Benefit You?

Cloves: Boost Your Immune System the Sweet and Spicy Way

The Many Potential Health Benefits of Curcumin

8 Chia Seed Recipes

Cinnamon Health Benefits Proven

 
Print Page
Email Article

New Research Suggests Garlic Compounds May Fight Malaria and Cancer

  [ 5 votes ]   [ Discuss This Article ]
By Ian Crandall, et al., University of Toronto • www.ProHealth.com • November 15, 2001





A group of compounds commonly found in garlic may not only be an effective treatment for malaria - the mechanism by which they inhibit the infection appears to be similar to the mechanism they use to fight cancer cells.

Researchers from the University of Toronto reported these findings in early November 2001 at the 50th Annual Meeting of the American Society of Tropical Medicine and Hygiene in Atlanta.

"Does eating garlic influence the outcome of malaria? There is evidence that yes, it may," says Ian Crandall, Assistant Professor of Laboratory Medicine and Pathobiology at the University of Toronto, who presented the study.

The compounds, called disulfides, occur naturally in garlic, onions and mahogany trees and are known to have antifungal, anticancer and antibacterial properties.

For years scientists have suspected that one of these compounds in garlic may be helpful against malaria and have proven it in animal models.

Crandall and his colleagues, though, were more interested in understanding how these disulfides worked against infection.

They tested 11 different synthetic disulfide compounds against malaria-infected cells. They also tested the effect of these compounds on cancer cells. While not all of the disulfides were effective against Plasmodium falciparum, the malaria parasite, those that were also effective at killing the cancer cells.

"We looked at the active compounds to see what they had in common. Apparently P. falciparum-infected cells and these cancer cells seem to have the same susceptibility profile," says Crandall.

Crandall believes that the mechanism of action may be on the glutathione system within the cell. In this system, the glutathione is reduced (the opposite of oxidation) and stored in the cell like energy in a battery. This reduced glutathione can then be brought out to absorb damage caused by oxygen and other harmful particles when needed.

The glutathione system is of particular importance in cells that rapidly reproduce, like cancer cells or malaria-infected cells, because these harmful particles are natural by-products of metabolism.

Ajoene, the disulfide that naturally occurs in garlic, is a known inhibitor of glutathione reduction. "Normal cells recharge glutathione and therefore are able to deal with the oxidative stress that normal metabolism generates, but in the presence of an inhibitor they cannot recharge and therefore are more prone damage and eventually death," says Crandall.

Crandall hopes that one days these compounds may be used to treat not only malaria, but some types of cancer as well. There is one drawback, though. "Does this stuff smell like garlic? Well, every time we open a vial of it in the lab everybody runs."



Post a Comment

Featured Products From the ProHealth Store
FibroSleep™ Ultra ATP+, Double Strength Energy NADH™ 12.5mg


Article Comments



Be the first to comment on this article!

Post a Comment


 
Optimized Curcumin Longvida with Omega-3

Featured Products

Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function

Natural Remedies

Enhance Eyelashes Naturally Enhance Eyelashes Naturally
Guarding Against the Dangers of Vitamin D Deficiency Guarding Against the Dangers of Vitamin D Deficiency
A Hard-Working Molecule that May Help Ease Pain & Brighten Mood A Hard-Working Molecule that May Help Ease Pain & Brighten Mood
Breakthrough Form of Magnesium Enhances Memory and Cognitive Function Breakthrough Form of Magnesium Enhances Memory and Cognitive Function
Strengthen Cell Function with Energy-Boosting Niagen Strengthen Cell Function with Energy-Boosting Niagen

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map