ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Inflammation Disrupts Memory - What Can You Do to Protect Your Brain?

All About Ginkgo Biloba: Benefits of This Timeless Herbal Supplement

Yarrow Oil: Here's Why It Deserves a Place in Your First-Aid Kit

Artificial sweeteners linked to risk of weight gain, heart disease and other health issues

Vitamin D supplement use associated with lower risk of breast cancer

Carnitine deficiency suggested as contributor to autism

Hop Oil: A Safe Sleep Aide

Lutein — An Important Nutrient for Eye and Brain Health

White Camphor Oil: The Purest Camphor Oil

Taurine: Facts About This Crucial Amino Acid

 
Print Page
Email Article

Link between Obesity and Breast Cancer Identified

  [ 36 votes ]   [ Discuss This Article ]
www.ProHealth.com • November 20, 2002


Leptin, the growth factor associated with weight gain, has been found to promote breast cancer cell growth, according to research published in the Nov. 20 issue of the Journal of the National Cancer Institute. The research also found a lack of leptin or its receptor is associated with a lack of breast tissue development in mice.

Previous research identified an association between obesity and breast cancer, but scientists were unsure of what was responsible for linking these two diseases. New research, led by University of Minnesota researcher Margot Cleary, Ph.D., may close that gap in understanding.

"These findings may explain why weight gain, which is accompanied by higher than expected leptin concentrations, also has been associated with increased breast cancer risk," said Cleary. "Preventive measures need to be taken to control these deadly diseases."

Obesity is considered a risk factor for breast cancer, and women who are obese tend, at the time of diagnosis, to have more aggressive disease with a poorer prognosis. Increased leptin levels have been tied to increased body fat levels and obesity.

Research conducted at the University of Minnesota's Hormel Institute, in collaboration with researchers at the Mayo Clinic, found that leptin enhanced the proliferation of both normal and cancerous breast cells.

The study shows that, in the presence of leptin, the number of cancerous breast cells increased 150 percent as compared to 50 percent for normal breast cells. In addition, leptin receptors, the docking sites responsible for signaling various metabolic activities within the cells, were identified.

In a test used to assess the cells' ability to form tumors, it was found that only the breast cancer cell line exposed to leptin responded, supporting the idea that leptin can promote tumor growth and development. Evidence that leptin promotes breast cancer tumor development provides an explanation of why obesity and breast cancer are associated.

Future studies should focus on determining whether the presence of leptin receptors in breast tumors is associated with those factors commonly assessed during breast cancer diagnosis, such as hormonal receptors, said Cleary.



Post a Comment

Featured Products From the ProHealth Store
Energy NADH™ 12.5mg FibroSleep™ Mitochondria Ignite™ with NT Factor®


Article Comments



Be the first to comment on this article!

Post a Comment


 
NAD+ Ignite with Niagen

Featured Products

Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function

Natural Remedies

Inflammation Disrupts Memory - What Can You Do to Protect Your Brain? Inflammation Disrupts Memory - What Can You Do to Protect Your Brain?
Front Line Defense Against Colds & Flu - Support for Healthy Immune System Balance Front Line Defense Against Colds & Flu - Support for Healthy Immune System Balance
Restore Youthful Cognition and Well-Being Restore Youthful Cognition and Well-Being
IBS, Crohn’s Disease, Colitis, and Other Digestive Disorders IBS, Crohn’s Disease, Colitis, and Other Digestive Disorders
The Crucial Role CoQ10 Plays in Fibromyalgia and ME/CFS The Crucial Role CoQ10 Plays in Fibromyalgia and ME/CFS

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map