ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

B Vitamins May Protect Against Damaging Effects of Air Pollution, and Improve Cognition and Psychiat...

Relief for IBS, Colitis, Crohn’s And More

Can Magnesium Relieve Your Tinnitus?

Restless Leg Syndrome (RLS) - are you running a marathon each night?

Resveratrol Proven to Slow Brain Aging

Magnesium Protects Against Stroke, Heart Disease and Diabetes

Fruits and vegetables' latest superpower? Lowering blood pressure

Neroli Oil: The Pleasantly Fragrant Citrus Oil

Restoring NAD+ could reduce DNA damage accumulation

Whole-body vibration may be as effective as regular exercise

 
Print Page
Email Article

Researchers release baseline data from randomized colorectal cancer screening trial

  [ 126 votes ]   [ Discuss This Article ]
www.ProHealth.com • December 4, 2002


A major trial is under way to determine the impact of single screening sigmoidoscopy on colorectal cancer incidence and mortality. Although the trial will take years to complete, outcomes from the recruitment and screening phases of the trial suggest that single screening sigmoidoscopy has a high cancer detection rate and is relatively safe and acceptable to patients. The findings appear in the December 4 issue of the Journal of the National Cancer Institute.

Scientists believe that colorectal cancers develop from adenomous polyps (abnormal growths) over a period of 10 to 15 years. Some have proposed that a single screening sigmoidoscopy around age 60 is a cost-effective approach to screening people for colorectal cancer. A sigmoidoscopy involves inserting a short, lighted tube into the rectum to check the colon wall for cancer and other abnormalities.

SCORE is a multicenter randomized controlled trial in Italy designed to measure the extent of reduction in colorectal cancer incidence and mortality achieved by a single screening sigmoidoscopy examination and to determine both the optimum age range for screening and how long the protective effect lasts.

Nereo Segnan, M.D., and his colleagues from the SCORE Working Group in Italy randomly assigned 34,292 people aged 55 to 64 to either an intervention group that was invited to undergo a sigmoidoscopy or a control group that was not invited for screening. Screenees who were found to have colorectal cancer or high risk polyps were referred for further testing with colonoscopy.

Of the people examined by sigmoidoscopy, 10.8% were found to have adenomas in the left side of the colon, the side closest to the rectum. Of the people who underwent further testing with colonoscopy, 15.5% were found to have adenomas in the right side of the colon. Colorectal cancers were found in 54 of the participants, a rate of 5.4 per 1,000. Furthermore, the procedures appeared relatively safe, with one perforation in nearly 10,000 sigmoidoscopy exams and one perforation in nearly 800 colonoscopies. There was also one hemorrhage requiring hospitalization after polypectomy (removal of a polyp). More than 80% of those screened described the associated pain as mild or less than expected.

"In conclusion, the baseline results from the SCORE trial show that sigmoidoscopy can be an acceptable and safe screening strategy for colorectal cancer," the authors write. "The high yield of advanced lesions and early colorectal cancer is consistent with the projected substantial impact of sigmoidoscopy screening on colorectal cancer incidence and mortality."



Post a Comment

Featured Products From the ProHealth Store
Energy NADH™ 12.5mg Optimized Curcumin Longvida® Mitochondria Ignite™ with NT Factor®

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
NAD+ Ignite with Niagen

Featured Products

Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils

Natural Remedies

Physically and Mentally Exhausted? How to Restore Energy at Its Source Physically and Mentally Exhausted? How to Restore Energy at Its Source
Why Berries Offer a Rainbow of Health Benefits Why Berries Offer a Rainbow of Health Benefits
More Weight Loss than Any Other Discovery in Supplement History More Weight Loss than Any Other Discovery in Supplement History
Top 3 Nutrients to Detox the Liver and Soothe Digestion Top 3 Nutrients to Detox the Liver and Soothe Digestion
Aches and Pains? A Simple Solution You'll Love Aches and Pains? A Simple Solution You'll Love

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map