ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Can Autoimmune Conditions be Reversed? Researchers Make a Surprising Discovery

Scientifically-designed fasting diet lowers risks for major diseases

How One Tiny Molecule Turned into One Huge Health Breakthrough

Acupuncture boosts effectiveness of standard medical care for chronic pain, depression

Research on Astaxanthin Demonstrates Significant Whole Body Benefits

Humans have three times more brown body fat

Nutrients Boost Stem Cell Function

B12 Proven Essential for Every Cell

Soy isoflavones may benefit breast cancer patients

Dietary prebiotics improve sleep, buffer impacts of stress, says study

 
Print Page
Email Article

Researchers release baseline data from randomized colorectal cancer screening trial

  [ 126 votes ]   [ Discuss This Article ]
www.ProHealth.com • December 4, 2002


A major trial is under way to determine the impact of single screening sigmoidoscopy on colorectal cancer incidence and mortality. Although the trial will take years to complete, outcomes from the recruitment and screening phases of the trial suggest that single screening sigmoidoscopy has a high cancer detection rate and is relatively safe and acceptable to patients. The findings appear in the December 4 issue of the Journal of the National Cancer Institute.

Scientists believe that colorectal cancers develop from adenomous polyps (abnormal growths) over a period of 10 to 15 years. Some have proposed that a single screening sigmoidoscopy around age 60 is a cost-effective approach to screening people for colorectal cancer. A sigmoidoscopy involves inserting a short, lighted tube into the rectum to check the colon wall for cancer and other abnormalities.

SCORE is a multicenter randomized controlled trial in Italy designed to measure the extent of reduction in colorectal cancer incidence and mortality achieved by a single screening sigmoidoscopy examination and to determine both the optimum age range for screening and how long the protective effect lasts.

Nereo Segnan, M.D., and his colleagues from the SCORE Working Group in Italy randomly assigned 34,292 people aged 55 to 64 to either an intervention group that was invited to undergo a sigmoidoscopy or a control group that was not invited for screening. Screenees who were found to have colorectal cancer or high risk polyps were referred for further testing with colonoscopy.

Of the people examined by sigmoidoscopy, 10.8% were found to have adenomas in the left side of the colon, the side closest to the rectum. Of the people who underwent further testing with colonoscopy, 15.5% were found to have adenomas in the right side of the colon. Colorectal cancers were found in 54 of the participants, a rate of 5.4 per 1,000. Furthermore, the procedures appeared relatively safe, with one perforation in nearly 10,000 sigmoidoscopy exams and one perforation in nearly 800 colonoscopies. There was also one hemorrhage requiring hospitalization after polypectomy (removal of a polyp). More than 80% of those screened described the associated pain as mild or less than expected.

"In conclusion, the baseline results from the SCORE trial show that sigmoidoscopy can be an acceptable and safe screening strategy for colorectal cancer," the authors write. "The high yield of advanced lesions and early colorectal cancer is consistent with the projected substantial impact of sigmoidoscopy screening on colorectal cancer incidence and mortality."



Post a Comment

Featured Products From the ProHealth Store
Ultra ATP+, Double Strength Ultra EPA  - Fish Oil Optimized Curcumin Longvida®

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
NAD+ Ignite with Niagen

Featured Products

Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength

Natural Remedies

Priming Your Immune System for Cold & Flu Season Priming Your Immune System for Cold & Flu Season
Running on Empty? Fuel Up with NADH Running on Empty? Fuel Up with NADH
Olea25 Olive Hydroxytyrosol Hits Astonishing 68,000+ ORAC Antioxidant Value Olea25 Olive Hydroxytyrosol Hits Astonishing 68,000+ ORAC Antioxidant Value
Bone Broth Benefits for Digestion, Arthritis and Cellulite Bone Broth Benefits for Digestion, Arthritis and Cellulite
Pioneer Scientists Uncover a Revolutionary Neuroprotective Supplement for Nerve Health Pioneer Scientists Uncover a Revolutionary Neuroprotective Supplement for Nerve Health

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map