ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

10 Fibro-Friendly Foods with a Bonus: Beautiful Skin

Studies Show that Magnesium L-threonate Improves Brain Plasticity, Leading to Direct and Significant...

Clary Sage Oil May Be Pricey, but Its Benefits Are Priceless

Pumpkin Pie Turmeric Breakfast Smoothie - Vegan + Gluten-Free

Component of red wine, grapes can help to reduce inflammation, study finds

Poly MVA: A Novel Therapy for Increasing Energy, Repairing DNA, and Promoting Overall Health

Vitamin D supplementation extends life in mouse model of Huntington's disease

Omega-3 fatty acid stops known trigger of lupus

Conquer Your Email Inbox, Increase Productivity and Reduce Stress

The Significance of Selenium

Print Page
Email Article

Researchers Discover Mechanism That May Trigger Autoimmune Disease

  [ 148 votes ]   [ Discuss This Article ] • May 5, 2003

In animal studies, researchers at the University of Virginia Health System have discovered a mechanism that may trigger autoimmune disease in newborn babies. The research is published in the May, 2003 issue of the Journal of Immunology.

The researchers found that certain antibodies in female mice attached to an antigen in the cells of their babies. That process then stimulated a response by T-cells, which attacked the ovaries of the baby mice. Eighty to 90 percent of the baby mice had ovarian destruction or inflammation in the study, an indication of autoimmune disease.

Usually, T-cells help direct and control the immune response and are important in the destruction of invaders in the body such as viruses, bacteria and cancer. T-cells also are required for optimum production of antibodies. But under abnormal conditions, the same T-cells can turn on the body's own cells and cause autoimmune disease.

"The findings were unexpected," said Kenneth S. K. Tung, a professor of pathology and microbiology at U.Va. "This suggests that autoimmune disease, in addition to a genetic influence, also has an environmental and non-genetic influence. It is really a new paradigm, a new way of thinking about autoimmune disease."

Tung and his colleagues also found that there is a time window in which exposure to the mother's antibody is critical for development of autoimmune disease. Mice exposed to the maternal antibody did not develop autoimmune disease after the first five days of life. Tung believes that's because special cells that control the action of T cells weren't functioning in the early days of life.

Mice transfer antibodies to their offspring through milk. In humans, the transfer of antibodies from mother to baby happens through the placenta during pregnancy, Tung says.

Autoimmune disease occurs when the normal tolerance of the body to its own cells disappears and healthy cells are attacked. Diabetes mellitus, rheumatoid arthritis, lupus and multiple sclerosis are types of autoimmune disease.

Post a Comment

Featured Products From the ProHealth Store
Mitochondria Ignite™ with NT Factor® Vitamin D3 Extreme™ Ultra EPA  - Fish Oil

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products

Article Comments

Be the first to comment on this article!

Post a Comment

Natural Pain Relief Supplements

Featured Products

Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function

Natural Remedies

Coping When Colds or Flu Catch Up with You Coping When Colds or Flu Catch Up with You
The Fast-Acting Solution for Healthy Digestive Function The Fast-Acting Solution for Healthy Digestive Function
Fatigue & Fibro Fog: Could You Have a B-12 Deficiency? Fatigue & Fibro Fog: Could You Have a B-12 Deficiency?
Rejuvenating the Brain - How PQQ Helps Power Up Mental Processing Rejuvenating the Brain - How PQQ Helps Power Up Mental Processing
Sleep Like a Baby in Nature's Cradle Sleep Like a Baby in Nature's Cradle

ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
Credit Card Processing
Be the first to know about new products, special discounts and the latest health news. *New subscribers only

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map