ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Basic Aromatherapy to Help Balance and Calm

Tea drinkers have lower glaucoma risk

Soy, cruciferous vegetables could help lower breast cancer treatment side effects

The Long-Term Benefits of Drinking Oolong Tea

Why You Should Try This Sweet-Smelling and Health-Boosting Essential Oil

Wonderful White Tea: A Drink Fit for an Emperor

Chamomile Tea: Why This Ancient Therapeutic Drink Still Stands Out Today

Arnica: This Powerful Herb Promotes Various Kinds of Healing

Get ‘Hooked’ on Cat’s Claw: The Many Benefits of This Amazonian Herb

Acid Reflux May Respond Better to Foods Than Prescribed Pills

 
Print Page
Email Article

Clinical Trial to Investigate Infliximab Therapy for Prevention of Rheumatoid Arthritis

  [ 75 votes ]   [ Discuss This Article ]
www.ProHealth.com • June 18, 2003


An international coalition of leading rheumatologists have announced the launch of the new DINORA trial that will investigate infliximab (Remicade®) in the treatment of pre-clinical rheumatoid arthritis (RA) to determine whether or not it can prevent the development of rheumatoid arthritis. DINORA was launched at the European League Against Rheumatism (EULAR) Annual Meeting and will be partially funded by Schering-Plough Corporation and Centocor, Inc.

“We anticipate very positive results from the ASPIRE trial (Active Controlled Study of Patients Receiving Infliximab for Treatment of Rheumatoid Arthritis of Early Onset) which looked at the combination of infliximab plus methotrexate in patients with early RA", said Peter Lipsky, MD, Scientific Director of the National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health. "DINORA will examine various combinations of infliximab and methotrexate in patients at an even earlier stage of RA -- some of whom are only a few weeks into the disease. We are now exploring the possibility of a cure for RA."




DINORA (Definitive Intervention in New-Onset Rheumatoid Arthritis) is a placebo controlled, double-blind, 12-month study, which will have a four-year follow-up period. The primary endpoint is absolute remission of disease -- the absence of all signs and symptoms of RA, at 12 months and 24 months. The DINORA study will have seven different treatment regimen arms, comparing methotrexate monotherapy, infliximab monotherapy, and infliximab/methotrexate combination therapy and placebo. Patients in DINORA will exhibit the entire spectrum of very early arthritis, as encountered in clinical practice. However, patients will be selected for the trial only if they have been diagnosed with arthritis in the last two to six weeks, and have had symptoms for no longer than six to 16 weeks.

Rheumatoid arthritis is a painful, crippling condition that affects an estimated 9.7 million people worldwide. This inflammatory disease causes swelling of joints, and leads to the deterioration and destruction of joint surfaces, and breakdown of bone. Within two years of disease onset, research shows joint destruction occurs within 50 to70 percent of RA patients and one-third become unable to continue working.



Post a Comment

Featured Products From the ProHealth Store
Vitamin D3 Extreme™ Mitochondria Ignite™ with NT Factor® Optimized Curcumin Longvida®


Article Comments



Be the first to comment on this article!

Post a Comment


 
Optimized Curcumin Longvida with Omega-3

Featured Products

FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health

Natural Remedies

Repair Damaged Mitochondria and Reduce Fatigue Up to 45% Repair Damaged Mitochondria and Reduce Fatigue Up to 45%
Carry a Massage Therapist in Your Pocket Carry a Massage Therapist in Your Pocket
Everything You Always Wanted to Know About Sleep But Were Too Tired to Ask Everything You Always Wanted to Know About Sleep But Were Too Tired to Ask
Natural Support for Mood, Sleep and Mental Focus? L-theanine Natural Support for Mood, Sleep and Mental Focus? L-theanine
Pioneer Scientists Uncover a Revolutionary Neuroprotective Supplement for Nerve Health Pioneer Scientists Uncover a Revolutionary Neuroprotective Supplement for Nerve Health

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2018 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map