ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

10 Fibro-Friendly Foods with a Bonus: Beautiful Skin

Studies Show that Magnesium L-threonate Improves Brain Plasticity, Leading to Direct and Significant...

Clary Sage Oil May Be Pricey, but Its Benefits Are Priceless

Pumpkin Pie Turmeric Breakfast Smoothie - Vegan + Gluten-Free

Component of red wine, grapes can help to reduce inflammation, study finds

Poly MVA: A Novel Therapy for Increasing Energy, Repairing DNA, and Promoting Overall Health

Vitamin D supplementation extends life in mouse model of Huntington's disease

Omega-3 fatty acid stops known trigger of lupus

Conquer Your Email Inbox, Increase Productivity and Reduce Stress

The Significance of Selenium

Print Page
Email Article

Clinical Trial to Investigate Infliximab Therapy for Prevention of Rheumatoid Arthritis

  [ 75 votes ]   [ Discuss This Article ] • June 18, 2003

An international coalition of leading rheumatologists have announced the launch of the new DINORA trial that will investigate infliximab (Remicade®) in the treatment of pre-clinical rheumatoid arthritis (RA) to determine whether or not it can prevent the development of rheumatoid arthritis. DINORA was launched at the European League Against Rheumatism (EULAR) Annual Meeting and will be partially funded by Schering-Plough Corporation and Centocor, Inc.

“We anticipate very positive results from the ASPIRE trial (Active Controlled Study of Patients Receiving Infliximab for Treatment of Rheumatoid Arthritis of Early Onset) which looked at the combination of infliximab plus methotrexate in patients with early RA", said Peter Lipsky, MD, Scientific Director of the National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health. "DINORA will examine various combinations of infliximab and methotrexate in patients at an even earlier stage of RA -- some of whom are only a few weeks into the disease. We are now exploring the possibility of a cure for RA."

DINORA (Definitive Intervention in New-Onset Rheumatoid Arthritis) is a placebo controlled, double-blind, 12-month study, which will have a four-year follow-up period. The primary endpoint is absolute remission of disease -- the absence of all signs and symptoms of RA, at 12 months and 24 months. The DINORA study will have seven different treatment regimen arms, comparing methotrexate monotherapy, infliximab monotherapy, and infliximab/methotrexate combination therapy and placebo. Patients in DINORA will exhibit the entire spectrum of very early arthritis, as encountered in clinical practice. However, patients will be selected for the trial only if they have been diagnosed with arthritis in the last two to six weeks, and have had symptoms for no longer than six to 16 weeks.

Rheumatoid arthritis is a painful, crippling condition that affects an estimated 9.7 million people worldwide. This inflammatory disease causes swelling of joints, and leads to the deterioration and destruction of joint surfaces, and breakdown of bone. Within two years of disease onset, research shows joint destruction occurs within 50 to70 percent of RA patients and one-third become unable to continue working.

Post a Comment

Featured Products From the ProHealth Store
Vitamin D3 Extreme™ Optimized Curcumin Longvida® Mitochondria Ignite™ with NT Factor®

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products

Article Comments

Be the first to comment on this article!

Post a Comment

Natural Pain Relief Supplements

Featured Products

Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%

Natural Remedies

Improve Cardiovascular and Metabolic Health with Omega-7 Improve Cardiovascular and Metabolic Health with Omega-7
Complete and Natural Menopause Relief Complete and Natural Menopause Relief
Everything You Always Wanted to Know About Sleep But Were Too Tired to Ask Everything You Always Wanted to Know About Sleep But Were Too Tired to Ask
Front Line Defense Against Colds & Flu - Support for Healthy Immune System Balance Front Line Defense Against Colds & Flu - Support for Healthy Immune System Balance
Relief for Dry, Itchy Skin Caused by Fibromyalgia Relief for Dry, Itchy Skin Caused by Fibromyalgia

ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
Credit Card Processing
Be the first to know about new products, special discounts and the latest health news. *New subscribers only

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map