ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Is a Good Night's Sleep at the Top of Your Wishlist?

Ashwagandha Helps Hormones - Aids Arthritis

Why You Should Be Eating More Porcini Mushrooms

A Breathalyzer for Disease?

How Bacopa Can Help Improve Your Cognitive Function

Magnesium Reduces Diabetes and Helps Keep You Young

Lavender Aromatherapy Can Ease Pre-Op Anxiety

Give Your Health a Much-Needed Boost With Geranium

The Role of Resveratrol in Achieving Optimal Health

Could Coconut Oil Help Reduce Antibiotics?

 
Print Page
Email Article

Prions and Alzheimer's Disease

  [ Not Yet Rated ]   [ Discuss This Article ]
By Report by the AD Educ and Referral Ctr • www.ProHealth.com • March 21, 1999


The journalists also had the rare opportunity of hearing a Nobel Laureate describe his work. Dr. Stanley Prusiner, of the University of California at San Francisco, winner of the Nobel Prize in Physiology or Medicine in 1997, took time for the journalists that morning, prior to delivering NIA’s prestigious Florence Mahoney Lecture that afternoon. Dr. Prusiner discussed his work on a novel class of protein-like infectious particles, dubbed prions. Well known in the research community, these "infectious proteins," or prion proteins (PrP), cause several neurodegenerative diseases, including Creutzfeldt-Jakob disease in humans, scrapie in sheep, and bovine spongiform encephalopathy (BSE), otherwise known as "mad cow disease." Dr. Prusiner’s research has turned a once obscure corner of medicine into an important source of new ideas about fundamental biological mechanisms in the etiology of these diseases.

Both prion diseases and AD cause dementia and death and are each associated with insoluble protein deposits that result in cell death. For example, once the brain is infected in scrapie, PrPsc (scrapie prion protein) accumulates and causes nerve cells (neurons) to malfunction. These PrPsc deposits, or plaques, consist chiefly of protein fragments collectively called amyloid. In AD, the amyloid is formed from a protein fragment named beta-amyloid, which itself is clipped from the larger protein APP. NIA-funded researchers have studied amyloid formation in prion diseases, and their findings may be useful in studying the pathway by which plaques are formed in AD.

Dr. Prusiner described his lab’s recent experiments in transgenic mice, which show promise for one day determining, for the first time, the levels of prions in brain and other tissues. Further research may lead to ways to stop the transmission of prion diseases between animal species and between animals and humans. It also will lead to an understanding of the biological mechanisms behind protein malformations in other types of dementia-related diseases, including AD. And finally, it will suggest avenues of research for new treatment strategies for both prion diseases and other dementia-related diseases. Currently, prion research involves primarily animal models and cell cultures. The development of new technologies, Dr. Prusiner stressed, is needed to advance this field of infectious proteins.


Source: Connections Magazine [Volume 8(1), Spring 1999]



Post a Comment

Featured Products From the ProHealth Store
Ultra EPA  - Fish Oil Vitamin D3 Extreme™ Mitochondria Ignite™ with NT Factor®


Article Comments



Be the first to comment on this article!

Post a Comment


 
Optimized Curcumin Longvida with Omega-3

Featured Products

Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength

Natural Remedies

Coconut Oil - Healthy Gifts from the 'Tree of Life' Coconut Oil - Healthy Gifts from the 'Tree of Life'
Vital Molecule Increases Cellular Energy and Improves Cognitive Function Vital Molecule Increases Cellular Energy and Improves Cognitive Function
Red Yeast Rice - Natural Option for Supporting Healthy Cholesterol Red Yeast Rice - Natural Option for Supporting Healthy Cholesterol
Supercharge Your Brain with Two Powerful Nutrients Supercharge Your Brain with Two Powerful Nutrients
Research Links Green Tea to Weight Loss Research Links Green Tea to Weight Loss

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map