ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Is a Good Night's Sleep at the Top of Your Wishlist?

Ashwagandha Helps Hormones - Aids Arthritis

Why You Should Be Eating More Porcini Mushrooms

A Breathalyzer for Disease?

How Bacopa Can Help Improve Your Cognitive Function

Black Tea Is Great for Your Gut

Magnesium Reduces Diabetes and Helps Keep You Young

Lavender Aromatherapy Can Ease Pre-Op Anxiety

Give Your Health a Much-Needed Boost With Geranium

The Role of Resveratrol in Achieving Optimal Health

 
Print Page
Email Article

Exercise and Dietary Changes Can Kill Prostate Cancer Cells, UCLA Scientists Report

  [ 70 votes ]   [ Discuss This Article ]
www.ProHealth.com • January 15, 2003


UCLA scientists report that 11 days of daily exercise and the Pritikin low-fat, high-fiber diet induce prostate cancer cells to die. The research, published in the new issue of the journal Cancer Causes and Control, is the first to show that diet and exercise can kill prostate cancer cells.

"You can make changes in a short period of time that have a dramatic impact on your health — in this case, on the growth and death of prostate tumor cells," said R. James Barnard, professor of physiological science at UCLA and lead investigator on the study.

Barnard and his UCLA colleagues studied two groups of men: 14 obese men, ages 42 to 73, without prostate cancer, who participated in an 11-day diet and exercise program at the Pritikin Longevity Center; and 8 men, ages 38 to 74, who have exercised regularly and followed a low-fat, high-fiber diet for more than 14 years.

The researchers collected blood serum samples from the 14 men before they began the 11-day Pritikin program. At UCLA, the researchers mixed these serum samples in dishes with prostate cancer cells. At the end of the 11-day program, the researchers collected a second set of blood serum samples from the same 14 men, and placed these samples in laboratory dishes with prostate cancer cells.

Prostate cancer cell death

Among the 14 men at the beginning of their diet and exercise program, fewer than three percent of the LNCaP cells — prostate cancer cells — in the cell culture showed apoptosis (programmed cell death). At the conclusion of the 11-day program, more than 40 percent of these cells were on their way to death, and in the 14-year group of eight men, more than 50 percent of these cells were on their way to apoptosis, or death.

"That was the finding that made our jaws drop," Barnard said. "We don't know yet whether these dramatic changes that occurred to prostate cancer cells cultured in a laboratory will also occur in patients; we have hope that these changes will occur."

In an attempt to understand what might be inducing the apoptosis of the tumor cells, the scientists measured blood serum levels of a hormone called IGF-I, which stimulates tumor cells to grow; a high level of IGF-I is a risk factor for prostate cancer, Barnard said.

At the end of the 11 days, IGF-I levels for the 14 men had decreased by 20 percent. The eight men who had followed the diet and exercise program for 14 years had IGF-I levels 55 percent lower than the 14 men had at the start of their diet and exercise program.

"Insulin is the primary factor that stimulates the liver to produce IGF-I," Barnard said. "In previous research, we have shown that diet and exercise lower the serum insulin level; we suspected that diet and exercise should lower the IGF-I level as well, and we have found that to be true."

While IGF-I floats in the bloodstream, it binds to a protein, IGFBP-I, which limits the amount of IGF-I that is available to interact with tissue. Higher levels of this binding protein are desirable, causing a drop in free IGF-I levels, Barnard said.

Over the 11-day program, IGFBP-I levels increased by 53 percent, while in the long-term group of eight men, IGFBP-I levels were 150 percent higher than the short-term group had at the outset of the program.

"We didn't expect the results would be this dramatic," Barnard said. "We found dramatic changes in both IGF-I and IGFBP-I levels with diet and exercise. The important message is you can change your levels of both IGF-I and IGFBP-I in a very short period of time, and that may have an important impact on your prostate health."

"I've been telling people for years if they want to avoid most of the health problems we have in this country, they should go on a low-fat, high-fiber diet and do about an hour of aerobic exercise every day," Barnard said. "You make up your mind: Do you want to be healthy? It's not a tough choice."

Barnard, 65, has worked with the Pritikin Longevity Center since 1978, and serves as a consultant. He weighs five pounds less than when he graduated from college, and his cholesterol dropped from 235 when he was in his early 40s to 180 when he changed his diet; he has maintained his cholesterol around 180–190 for more than 20 years.

The Pritikin program focuses on a diet of whole grains, fruits and vegetables, and small portions of meat (no more than 3-and-a-half ounces a day), and 60 minutes of exercise a day.

Prostate cancer is the most common type of cancer in American men, other than skin cancer, and the second leading cause of cancer death in men, exceeded only by lung cancer. Some 30,000 men in the United States die of prostate cancer each year.



Post a Comment

Featured Products From the ProHealth Store
Energy NADH™ 12.5mg Ultra ATP+, Double Strength Optimized Curcumin Longvida®


Article Comments



Be the first to comment on this article!

Post a Comment


 
Optimized Curcumin Longvida with Omega-3

Featured Products

Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%

Natural Remedies

Restoring Gut Health: How to Create a Firewall Against Toxins Entering the Gut Wall Restoring Gut Health: How to Create a Firewall Against Toxins Entering the Gut Wall
Are You Obtaining the Proper Enzymes? Are You Obtaining the Proper Enzymes?
Reversing Neurodegeneration with a New Magnesium Compound Reversing Neurodegeneration with a New Magnesium Compound
Olea25 Olive Hydroxytyrosol Hits Astonishing 68,000+ ORAC Antioxidant Value Olea25 Olive Hydroxytyrosol Hits Astonishing 68,000+ ORAC Antioxidant Value
Health Benefits Are Brewing in Green Tea Health Benefits Are Brewing in Green Tea

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map