ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Vitamin D supplements, sleep could help manage pain

Bacopa: The Herb That May Increase Your Brain Power

Eat More Yogurt and Avoid Osteoporosis

Lilac Oil: More Than Just for Fragrance

What Is Bilberry Good For?

Coffee, herbal tea may help prevent liver fibrosis

Crafty Uses for Carrot Seed Oil

Higher omega 3 levels linked to improved brain blood flow

Curcumin, resveratrol, ursolic acid show promise against prostate cancer

Olive oil compound could help protect against brain cancer

 
Print Page
Email Article

NIH Scientists Find Nicotinic Receptor in Brain: May Help to Explain Epilepsy, Alzheimer's, Addiction

  [ Not Yet Rated ]   [ Discuss This Article ]
By Press Release by the National Institute on Aging • www.ProHealth.com • November 5, 1997


Two scientists of the National Institute of Environmental Health Sciences have found evidence for a new role for a specialized neurotransmitter receptor, the nicotinic receptor, in a region of the brain that is thought to be important in learning and memory processes, the hippocampus.

The researchers believe their discovery provides a "molecular mechanism" that may help to explain some of the pathology of a certain form of epilepsy, Alzheimer's and Parkinson's diseases, nicotine addiction, and depression.
Neurotransmitter receptors are specialized molecules located on the outside of cells. A neurotransmitter binds to the receptor and, in effect, carries information into the cell. The natural neurotransmitter that ordinarily binds to this nicotinic receptor and carries messages throughout the nervous system and the brain is acetylcholine, a chemical released from one nerve cell to elicit an electrical signal in the next cell within the circuit.

Although acetylcholine is the usual "activator" of this receptor, it is also so-named as it binds and responds to nicotine. The scientists said that this nicotinic receptor, to which nicotine binds, exists in a subset of nerve cells in the hippocampus. This receptor was studied through a technique which records electrical nerve impulses in individual nerve cells. The researchers -- Susan Jones, Ph.D., and Jerrel L. Yakel, Ph.D., worked with thin slices of rat hippocampus which is similar to, but much smaller than, a human's. The scientists reported their work in the Journal of Physiology, Volume 504, #3.

Both are with the Laboratory of Signal Transduction at NIEHS, an Institute of NIH, located in Research Triangle Park, N.C.

Dr. Yakel said the identification of this receptor in the hippocampus may have relevance to nicotine's apparent enhancement of memory in some Alzheimer's patients, nicotine addiction, and a rare form of epilepsy.
The receptor's function may be a key to understanding epilepsy and Alzheimer's disease, Dr. Jones added, but it may also be important in other diseases such as Parkinson's or depression. "Basic research like this can ultimately lead to disease-specific solutions," Dr. Jones said.

Source:
National Institute on Aging
Press release
November 5, 1997



Post a Comment

Featured Products From the ProHealth Store
Vitamin D3 Extreme™ Ultra EPA  - Fish Oil Ultra ATP+, Double Strength

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
NAD+ Ignite with Niagen

Featured Products

FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils

Natural Remedies

Aching Muscles? Top 10 Nutrients to Take Back Your Life Aching Muscles? Top 10 Nutrients to Take Back Your Life
Front Line Defense Against Colds & Flu - Support for Healthy Immune System Balance Front Line Defense Against Colds & Flu - Support for Healthy Immune System Balance
Bone Broth Benefits for Digestion, Arthritis and Cellulite Bone Broth Benefits for Digestion, Arthritis and Cellulite
Curcumin - a Golden Gift of Nature with Benefits Still Untold Curcumin - a Golden Gift of Nature with Benefits Still Untold
Live Without Anxiety or Stress Live Without Anxiety or Stress

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map