ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

SURVEY: Weight Management & Chronic Illness

Japanese green tea consumers have reduced risk of dementia

Do Nothing, Accomplish Everything! The Connection Between Breathing and Healing

Meet the ProHealth Editors

Best Herbs to Help With Insomnia

Choline: Why You Should Eat Your Egg Yolks and Take Krill

Calcium, vitamin D supplementation associated improved stroke recovery

Acupressure reduced fatigue in breast cancer survivors

More positive evidence for melatonin in breast cancer battle

Omega-3 shows promise as stroke treatment

 
Print Page
Email Article

Scientists Develop Mouse Model for Alzheimer's Disease

  [ Not Yet Rated ]   [ Discuss This Article ]
By Press Release by the National Institute on Aging • www.ProHealth.com • October 3, 1996


A new mouse model that will further understanding of Alzheimer's disease and ultimately allow for testing of drug therapies has been developed by scientists at the University of Minnesota. The genetically-engineered mouse is the first to exhibit both behavioral characteristics of Alzheimer's dementia and protein-derived plaques like those which appear in the brains of people with Alzheimer's disease.

Findings and Implications

The development of the transgenic mouse is described in the October 4, 1996, Science. Karen Hsiao, M.D., Ph.D., University of Minnesota, led a team of scientists from the Veterans Administration Medical Center, Sepulveda, California; the Mayo Clinic Jacksonville, Florida; and other institutions. The National Institute on Aging (NIA) and the National Institute of Neurological Disorders and Stroke (NINDS), both parts of the National Institutes of Health, supported the work along with the Alzheimer's Association.

Early in life, the transgenic mouse appeared normal. But later, at 9-10 months, the mice had considerable difficulty in a number of memory tasks when compared with a control group of similarly trained mice. The oldest transgenics also had between 5 and 14 times the amount of A-beta peptides associated with amyloid plaques as the younger, normal mice.

For years, scientists have been in disagreement as to whether the amyloid plaques cause Alzheimer's disease or whether they are a byproduct of some other process. "This is the first animal model to show that amyloid and deficits in learning and memory are associated," says D. Stephen Snyder, Ph.D., Program Director, Etiology of Alzheimer's Disease, NIA. "However, whether the deficits are caused by or merely correlate with the presence of amyloid remains unresolved. Further testing with this model may help us understand the relationship between plaques and behavior, something we need to know for the development of effective drug therapies."

Source:
National Institute on Aging
Press Release
October 3, 1996



Post a Comment

Featured Products From the ProHealth Store
Optimized Curcumin Longvida® Ultra EPA  - Fish Oil Vitamin D3 Extreme™

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
Natural Pain Relief Supplements

Featured Products

Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength

Natural Remedies

SAM-e: a Hard-Working Molecule that May Help Ease Pain & Brighten Mood SAM-e: a Hard-Working Molecule that May Help Ease Pain & Brighten Mood
The Brain Boosting and Fatigue Fighting B-12 The Brain Boosting and Fatigue Fighting B-12
Clinically Studied Joint Relief Product for FM & ME/CFS Clinically Studied Joint Relief Product for FM & ME/CFS
Can Glycine + Amino Acids Be the Secret to Deep, Rejuvenating Sleep? Can Glycine + Amino Acids Be the Secret to Deep, Rejuvenating Sleep?
Guarding Against the Dangers of Vitamin D Deficiency Guarding Against the Dangers of Vitamin D Deficiency

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE AND SAVE 15% NOW*
Be the first to know about new products, special discounts and the latest health news. *New subscribers only

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map