ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Is a Good Night's Sleep at the Top of Your Wishlist?

Ashwagandha Helps Hormones - Aids Arthritis

Why You Should Be Eating More Porcini Mushrooms

A Breathalyzer for Disease?

How Bacopa Can Help Improve Your Cognitive Function

Magnesium Reduces Diabetes and Helps Keep You Young

Lavender Aromatherapy Can Ease Pre-Op Anxiety

Give Your Health a Much-Needed Boost With Geranium

The Role of Resveratrol in Achieving Optimal Health

Could Coconut Oil Help Reduce Antibiotics?

 
Print Page
Email Article

Alzheimer protein found critical to brain development

  [ 27 votes ]   [ Discuss This Article ]
By Press Release by the Univ. of Toronto • www.ProHealth.com • October 31, 1999


Researchers from Mount Sinai Hospital's Samuel Lunenfeld Research Institute and the University of Toronto have discovered that some of the proteins responsible for familial Alzheimer's disease are also critical to mammalian development. The study is published in the November 1st edition of the journal Genes and Development.

Previous work in Toronto by Dr. Peter St. George Hyslop and others has shown that the human genes Presenilin 1 (PS1) and Presenilin 2 (PS2) are responsible for certain hereditary forms of Alzheimer's. To investigate how these proteins normally function, the Lunenfeld scientists developed mice lacking PS1 and PS2. These mutant mice do not survive past the early embryonic stage of development due to multiple defects, including brain development.

"The study shows that the same proteins that malfunction late in life have a key role in the beginning of life," said study author Dr. Alan Bernstein, director of the Samuel Lunenfeld Research Institute of Toronto's Mount Sinai Hospital and professor of medical genetics at the University of Toronto.
Post-doctoral researcher Dr. Dorit Donoviel, also of the Lunenfeld, said mice were used in the study because they are genetically and biochemically similar to humans. "These observations raise the intriguing possibility that early decisions in human development can have serious effects late in life," Dr. Donoviel says. "These mice will provide a valuable biological tool with which to understand the function of the molecules implicated in Alzheimer's Disease."

According to the Alzheimer Society of Canada there is no known cure for the disease that destroys vital nerve cells in the brain. Alzheimer Disease is the most common form of dementia, which affects 316,500 Canadians. The number is expected to grow to 750,000 Canadians affected by the year 2031.

The other study authors are: Anna-Katerina Hadjantonakis, Samuel Lunenfeld Research Institute of Mount Sinai Hospital; Masaki Ikeda, Centre for Research in Neurodegenerative Diseases and department of medicine, division of neurology, University of Toronto; Hui Zheng, Merck Research Laboratories, Rahway, New Jersey; Peter St. George Hyslop, Centre for Research in Neurodegenerative Diseases and department of medicine, division of neurology, University of Toronto and Toronto Western Hospital.

Source: University of Toronto Press Release: October 31, 1999

Contact: Steven de Sousa, steven.desousa@utoronto.ca, 416-978-5949



Post a Comment

Featured Products From the ProHealth Store
FibroSleep™ Optimized Curcumin Longvida® Energy NADH™ 12.5mg


Article Comments



Be the first to comment on this article!

Post a Comment


 
Optimized Curcumin Longvida with Omega-3

Featured Products

Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function

Natural Remedies

Herbal Inflammation Management for Whole Body Health Herbal Inflammation Management for Whole Body Health
Why Berries Offer a Rainbow of Health Benefits Why Berries Offer a Rainbow of Health Benefits
The Revolutionary 'Good Fat' That Promotes Heart, Brain, Bone and Joint Health The Revolutionary 'Good Fat' That Promotes Heart, Brain, Bone and Joint Health
The Fibromyalgia and Glutathione Link The Fibromyalgia and Glutathione Link
Joint Aches May Have Met Their Match in Curcumin Joint Aches May Have Met Their Match in Curcumin

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map