ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

B Vitamins May Protect Against Damaging Effects of Air Pollution, and Improve Cognition and Psychiat...

Relief for IBS, Colitis, Crohn’s And More

Can Magnesium Relieve Your Tinnitus?

Restless Leg Syndrome (RLS) - are you running a marathon each night?

Resveratrol Proven to Slow Brain Aging

Magnesium Protects Against Stroke, Heart Disease and Diabetes

Fruits and vegetables' latest superpower? Lowering blood pressure

Neroli Oil: The Pleasantly Fragrant Citrus Oil

Prenatal vitamin D could help prevent autism in children

Restoring NAD+ could reduce DNA damage accumulation

 
Print Page
Email Article

Leflunomide Is Safe, Effective for Rheumatoid Arthritis

  [ 69 votes ]   [ Discuss This Article ]
www.ProHealth.com • February 4, 2004


Leflunomide is a safe and effective treatment in patients with active rheumatoid arthritis, according to a European team of researchers. Dr. Maxime Dougados, from Hopital Cochin, Paris, and colleagues examined the safety and efficacy of leflunomide, one of a novel class of disease modifying antirheumatic drugs (DMARD), that may be achieved in clinical practice. They report the results of the first phase of the RELIEF study, which involved a 24-week, open-label cohort, in the December issue of the Journal of Rheumatology. The 969 participants received 100 mg leflunomide once daily for 3 days, followed by 20 mg once daily thereafter. The team recorded all adverse events. Efficacy variables included the European League Against Rheumatism (EULAR) response criteria using the Disease Activity Score (DAS 28) responder rate and the response rate according to American College of Rheumatology (ACR) criteria.

The team observed no adverse events that had not previously been reported with leflunomide. Of the 968 evaluable patients, 69.6% were responders according to DAS 28 and 60.6% were responders according to ACR criteria. "There was a high correlation between the EULAR and ACR criteria in determining treatment response," Dr. Dougados and colleagues report. They found that at study endpoint, 24.8% had low disease activity and 12.7% met the criteria for disease remission. Overall, the findings "confirm the acceptable safety profile and clinical efficacy of leflunomide in patients with active RA," they write. The data also suggest that this drug is effective "across a broad range of patient characteristics as there were no clinically significant differences in predisposing factors to treatment response." J Rheumatol 2003;30:2572-2579. Source: Medscape



Post a Comment

Featured Products From the ProHealth Store
FibroSleep™ Mitochondria Ignite™ with NT Factor® Optimized Curcumin Longvida®

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
NAD+ Ignite with Niagen

Featured Products

Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%

Natural Remedies

Can Autoimmune Conditions be Reversed? Researchers Make a Surprising Discovery Can Autoimmune Conditions be Reversed? Researchers Make a Surprising Discovery
Fatigue & Fibro Fog: Could You Have a B-12 Deficiency? Fatigue & Fibro Fog: Could You Have a B-12 Deficiency?
Block food Cravings At Their Molecular Root Block food Cravings At Their Molecular Root
Thyroid Health and Fibromyalgia Thyroid Health and Fibromyalgia
Fighting Fatigue with Ground-breaking French Oak Wood Extract Fighting Fatigue with Ground-breaking French Oak Wood Extract

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map