ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Astaxanthin Is a Longevity Promoter

Meta-analysis links vitamin D deficiency with increased risk of mortality during 10.5 year median pe...

Prevent Or Reverse Diabetes: An Amazing Herbal Intervention

Exercise and Vitamin D Better Together for Heart Health

VIDEO: Essential Oils for Weight Loss

Can Valerian Root Help You Sleep Better?

Eight servings of veggies a day is clearly best for the heart

Can Ginkgo Give Your Brain a Boost?

Fighting Statin-Induced Diabetes with CoQ10

The Many Wonders of Calming Sandalwood Oil

 
Print Page
Email Article

Rewiring The Brain

  [ Not Yet Rated ]   [ Discuss This Article ]
By Andy Coghlan • www.ProHealth.com • June 17, 1998


A protein that helps broken bones and damaged kidneys to heal now looks as though it may speed the recovery of stroke patients. It works by rewiring the connections around damaged brain cells. There is also a chance that the protein may be able to improve memory in Alzheimer's patients. "It looks very encouraging at this point," says Marc Charette of Creative BioMolecules in Massachusetts, the company that is developing the protein. "The region of the brain that's damaged dies, but the protein rewires the circuitry around the damage, through tissue surviving the stroke," he says.

The experiment, reported in NeuroReport (vol. 9, p 1441), used rats in which the researchers had induced strokes. Osteogenic protein-1 (OP-1) was injected into their brains and it quickly helped them to recover lost movement in their limbs. OP-1 has already proved its ability to help bridge gaps between broken bones (New Scientist, Science, 18 December 1993, p 20) and Creative BioMolecules is now close to having the procedure approved by the US Food and Drug Administration. The company is also progressing with work showing that OP-1 helps to heal damaged kidneys (Technology, 25 May 1996, p 25).

The substance, a member of a family of proteins called transforming growth factor-b, seems to orchestrate the repair of several types of tissue. The company has established that OP-1 directs primordial stem cells to differentiate into tissue that matches the damaged tissue. When the company discovered that OP-1 triggers the growth of tendril-like projections on neurons, called dendrites, it decided to test the protein's potential for brain repair after strokes. "Dendrites receive signals from other neurons," says Charette. "They behave like a switchboard, so you can rewire around the damage."

To test OP-1 in rats after artificially induced strokes, Charette and his colleagues from Massachusetts General Hospital and Harvard Medical School injected it into the cisterna magna, a brain cavity containing cerebral fluid. Through tests that measured how easily the rats could place their limbs on a nearby platform, the researchers proved that rats on the higher dose-10 micrograms-recovered faster than those on the 1 microgram dose (see Graph). All the rats receiving OP-1 recovered far faster than those in the control group.

Source: New Scientist issue 20th June 1998, page 14

UK Contact: Claire Bowles, claire.bowles@rbi.co.uk, 44 171 331 2751

US Contact: Barbara Thurlow, newscidc@idt.net, 202 452 1178



Post a Comment

Featured Products From the ProHealth Store
Ultra EPA  - Fish Oil Vitamin D3 Extreme™ Optimized Curcumin Longvida®

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
NAD+ Ignite with Niagen

Featured Products

FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength

Natural Remedies

Itching to Find Dry Skin Relief? Itching to Find Dry Skin Relief?
The Remarkable Benefits of Reishi Medicinal Mushrooms The Remarkable Benefits of Reishi Medicinal Mushrooms
Natural Relief for Soreness, Pain and Swelling - Putting Out the Fire Natural Relief for Soreness, Pain and Swelling - Putting Out the Fire
Repair Damaged Mitochondria and Reduce Fatigue Up to 45% Repair Damaged Mitochondria and Reduce Fatigue Up to 45%
The Most Powerful Natural Antioxidant Discovered to Date - Hydroxytyrosol The Most Powerful Natural Antioxidant Discovered to Date - Hydroxytyrosol

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map