ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

SURVEY: Cognitive Impairment II

Natural Bladder Control, Go Less and Live More

Vital Molecule Increases Cellular Energy and Improves Cognitive Function

Top Vitamin and Mineral Deficiencies — Are You at Risk?

How Pomegranate May Protect Against Cancer

Omega Fix for Obesity: How the Right Fats Fight Fat

Trimming the spare tire: Canola oil may cut belly fat

The Onion: Cancer Fighter and Food Preserver

Fighting Heartburn and Gerd Naturally – And Safely!

Probiotics improve cognition in Alzheimer's patients

 
Print Page
Email Article

Nasal Spray for Arthritis Planned

  [ 58 votes ]   [ Discuss This Article ]
www.ProHealth.com • August 4, 2004


Drugs can be delivered via the nose

Scientists are developing a gene therapy treatment for rheumatoid arthritis (RA) that will come in the form of a nasal spray. Research is still at the laboratory stage, but the team at King's College, London, hope to start clinical trials within three years. The spray would contain a gene that controls production of a natural anti-inflammatory substance.

RA is a joint condition that affects around 350,000 people in the UK. This is exciting research with real potential to provide a new approach to therapy in rheumatoid arthritis. Preliminary tests by the King's team suggest nasal drops or a spray would be an effective way to deliver a shot of the key compound - called Interleukin-10.

Source: BBC news

This compound not only switches off the harmful, inflammatory process that causes RA, it also seems to stimulate cells that can hold the potentially harmful immune system cells in check. Other researchers have tested Interleukin-10 as a treatment for RA. However, when it is delivered by intravenous injection it has been shown to cause side effects such as generalised suppression of the immune system. The King's team is hopeful that administering the IL-10 gene via the nose will produce a more targeted effect, rather than affecting the whole immune system, so avoiding side effects. It could also be considerably cheaper than current immunotherapeutic drugs.

Lead researcher Dr Linda Klavinskis said: "Every step we take we are thinking about patients, and we hope this research will lead to a clinical trial when it is completed in three years' time." Dr Madeleine Devey, of the Arthritis Research Campaign which is helping to fund the research, said: "This is exciting research with real potential to provide a new approach to therapy in rheumatoid arthritis. "

Despite the development of TNFalpha antibody therapy for RA, there is still a need to develop more precise ways of modulating the immune system. "Plasmid therapy is a way of delivering a therapeutic gene to the site of inflammation safely and effectively. "If successful, this could provide an important way to specifically interfere with the disease process in RA without affecting the immune system as a whole. "This could provide long-term therapeutic benefits with fewer side effects and would be considerably less expensive than the existing biological therapies."



Post a Comment

Featured Products From the ProHealth Store
Ultra EPA  - Fish Oil FibroSleep™ Vitamin D3 Extreme™


Article Comments



Be the first to comment on this article!

Post a Comment


 
Natural Pain Relief Supplements

Featured Products

Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health

Natural Remedies

Repair Damaged Mitochondria and Reduce Fatigue Up to 45% Repair Damaged Mitochondria and Reduce Fatigue Up to 45%
Rejuvenating the Brain - How PQQ Helps Power Up Mental Processing Rejuvenating the Brain - How PQQ Helps Power Up Mental Processing
When a Good Night's Sleep Is Just a Daydream... When a Good Night's Sleep Is Just a Daydream...
How I Found My Long-Lost Energy How I Found My Long-Lost Energy
Can Glycine + Amino Acids Be the Secret to Deep, Rejuvenating Sleep? Can Glycine + Amino Acids Be the Secret to Deep, Rejuvenating Sleep?

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map