ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

15 Health Benefits of Chia Seeds, According to Science

Tangerine Oil: A Citrusy Essential Oil With Well-Rounded Uses

Magnesium Deficiency Raises Your Risk of Many Chronic Ailments

Resveratrol supplementation improves arterial stiffness in type 2 diabetics

CoQ10's Potential Capabilities for Your Health

Testosterone replacement therapy associated with improved urinary, sexual function

How Can Melatonin Benefit You?

Cloves: Boost Your Immune System the Sweet and Spicy Way

The Many Potential Health Benefits of Curcumin

8 Chia Seed Recipes

 
Print Page
Email Article

Parkinson’s Drug Linked to Heart Disease Risk Factor

  [ 59 votes ]   [ Discuss This Article ]
www.ProHealth.com • February 19, 2003


DALLAS - Feb. 19, 2003 – A drug used for the last 40 years to treat Parkinson’s disease increases blood levels of an amino acid that could put patients at increased risk for heart disease, according to researchers at UT Southwestern Medical Center at Dallas.

Doctors have suspected that the drug levodopa can elevate body levels of the amino acid homocysteine, which is associated with an increased risk of heart disease and stroke, said Dr. Ramon Diaz-Arrastia, associate professor of neurology.

In a study published in the Archives of Neurology, Diaz-Arrastia and his colleagues measured homocysteine levels in blood samples from 235 Parkinson's patients, including 201 who had been treated with levodopa.

“We did find that there is a statistically modest increased risk of heart disease in Parkinson’s patients with elevated homocysteine,” Diaz-Arrastia said.

The findings imply that patients being treated with levodopa should ask their neurologists to monitor the level of homocysteine in their blood, particularly if they are at risk for heart disease, Diaz-Arrastia said.

The conclusions should not prevent people from using levodopa, he said.

“This medicine is necessary for parkinsonism,” Diaz-Arrastia said. “It is very effective therapy, but physicians may need to pay attention to their patients’ homocysteine levels.”

Parkinson's disease leads to a reduction of dopamine, a brain chemical vital for controlling body movement. As a result, patients suffer from muscle tremors, rigidity of movement, and balance and coordination problems. Levodopa alleviates symptoms by replenishing lost stores of dopamine in the brain, but the drug does not cure the disorder or slow its progression.

Participants in the study who had received levodopa showed significantly higher levels of homocysteine in their blood than people who had not taken the drug. Patients with the highest homocysteine levels had an increased prevalence of coronary artery disease, according to the study; however, the retrospective nature of the study made it impossible to determine conclusively if levodopa therapy was responsible for the increased prevalence of vascular disease, Diaz-Arrastia said.

Low levels of vitamin B12 and folic acid are a common cause of increases in homocysteine levels in the blood. Deficiencies of these vitamins, however, did not explain the elevated homocysteine levels among patients who had used levodopa in the study.

Previous studies have suggested that high levels of homocysteine can also elevate the risk of dementia and depression.

“Homocysteine has gotten a lot of attention over the last 10 years or so as a risk factor for heart disease and has gotten even more attention lately as a risk factor for Alzheimer’s disease,” Diaz-Arrastia said.

About one-third of patients with Parkinson’s develop dementia. Diaz-Arrastia said the study raises the question of whether levodopa increases that risk.

Dr. Alan Frol, assistant professor of psychiatry at UT Southwestern, also participated in the study published in January 2003, as well as scientists from the Hyman-Newman Institute for Neurology and Neurosurgery at Beth Israel Medical Center in New York.

The study was funded by grants from the National Institutes of Health and the Institute for the Study of Aging.



Post a Comment

Featured Products From the ProHealth Store
Energy NADH™ 12.5mg Optimized Curcumin Longvida® Vitamin D3 Extreme™


Article Comments



Be the first to comment on this article!

Post a Comment


 
Optimized Curcumin Longvida with Omega-3

Featured Products

Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils

Natural Remedies

"It's Not Easy Being Green" - But It Is Healthy
How to Jump-start and Sustain Energy Production in CFS How to Jump-start and Sustain Energy Production in CFS
Probiotic Mint Promotes Healthy Gums & Teeth, Freshens Breath and Whitens Teeth Probiotic Mint Promotes Healthy Gums & Teeth, Freshens Breath and Whitens Teeth
Sunshine Vitamin Has D-lightful Health Benefits Sunshine Vitamin Has D-lightful Health Benefits
Running on Empty? Fuel Up with NADH Running on Empty? Fuel Up with NADH

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map