ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

On-and-off fasting helps fight obesity, study finds

Can Pomegranates Slow Aging?

Calorie restriction promotes longevity through effects on mitochondrial network

Discover Why Ashwagandha Can Be Used for Stress and Anxiety

Lower magnesium levels linked with increased mortality risk during up to 40 years of follow-up

A spoonful of oil: Fats and oils help to unlock full nutritional benefits of veggies, study suggests

Higher resveratrol dose linked to lower glucose levels in type 2 diabetics

How Can You Benefit From Vitamin B12?

Drug can dramatically reduce weight of people with obesity

What Is Bitter Orange?

 
Print Page
Email Article

NADH study reports long-term gains for Chronic Fatigue Syndrome

  [ 110 votes ]   [ Discuss This Article ]
By Source: Annals of Allergy • www.ProHealth.com • February 1, 1999


A nutritional supplement, NADH may be a valuable adjunctive therapy for CFS, according to a published report by a team of researchers at Georgetown University Medical Center in Washington, D.C. In a double-blind, placebo-controlled, cross-over study of 26 patients with CFS, Dr. Joseph Bellanti and colleagues reported that eight patients improved during the four weeks they were on NADH, while only two patients improved while on placebo. In a continuation of the study in which all the volunteers were knowingly taking the supplement, 72% (18 of 25 patients) reported significant improvement of their fatigue with no severe adverse effects from the supplement.

NADH (the reduced form of nicotinamide adenine dinucleotide) is a co-enzyme that triggers energy production in cells by generating ATP (adenosine triphosphate), which stores energy in cells. If cellular levels of NADH are depleted, brain and muscle cells lose their ability to function effectively. The theory is that as NADH levels rise in the body, the cells become more energized, making the body feel stronger and more energized.

This trial used a dosage of 10 mg per day (two tablets, taken 45 minutes before breakfast) of a patented, oral form of NADH manufactured under the brand name Enada by the European company Menuco.

This study was small, with just 26 patients, but it does appear to have been carefully controlled. The study protocol was approved by the Food and Drug Administration (FDA), which does not regulate the distribution of nutritional supplements but does regulate medical claims made for such products. This was the equivalent of a Phase II safety and efficacy trial.

Subjects were 17 women and nine men, ranging in age from 26 to 57, and they had experienced fatigue for an average of seven years (ranging from one to 16 years). One patient was African-American; 25 were Caucasian. All had fatigue, neurocognitive difficulties and sleep disturbances, and nearly all experienced postexertional malaise, headaches, muscle weakness, arthralgia, myalgias and a history of allergy. Eighteen had swollen or tender lymph nodes. There was no correlation between a specific symptom pattern or laboratory test results and response to treatment. Response was measured primarily by a subjective questionnaire, with at least a 10% improvement required to be considered a favorable response.

One of the subjects reported being overly stimulated, and the researchers suggested that patient’s dosage could have been decreased. Other non-responders may have benefited from an increased dosage. Dosages were not adjusted for weight in this study.

The study was published in the February 1999 issue of Annals of Allergy, Asthma and Immunology. A larger open-label study is planned at Georgetown. NADH also is being studied as a potential treatment for persons with Alzheimer’s disease and Parkinson’s disease.



Post a Comment

Featured Products From the ProHealth Store
Mitochondria Ignite™ with NT Factor® Ultra ATP+, Double Strength Optimized Curcumin Longvida®


Article Comments



Be the first to comment on this article!

Post a Comment


 
Optimized Curcumin Longvida with Omega-3

Featured Products

Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%

Natural Remedies

Repair Damaged Mitochondria and Reduce Fatigue Up to 45% Repair Damaged Mitochondria and Reduce Fatigue Up to 45%
More Weight Loss than Any Other Discovery in Supplement History More Weight Loss than Any Other Discovery in Supplement History
Enhance Eyelashes Naturally Enhance Eyelashes Naturally
The Brain Boosting and Fatigue Fighting B-12 The Brain Boosting and Fatigue Fighting B-12
Herbal Rescue for High Blood Sugar Herbal Rescue for High Blood Sugar

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map