ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Scientifically-designed fasting diet lowers risks for major diseases

Is Magnesium the Missing Link in Your Heart Healthy Routine?

More evidence for calorie restriction’s longevity effect

Supplementation with vitamin D associated with improved testosterone, erectile function among middle...

A Little Zinc Goes a Long Way

Vitamin D deficiency increases risk of chronic headache

VIDEO: The Best Brain Foods That Help Increase Your Memory!

Get the Most From Your Green Tea

Iron (And More) For Lasting, Natural Energy

Metabolic syndrome increases the need for vitamin E

 
Print Page
Email Article

NADH study reports long-term gains for Chronic Fatigue Syndrome

  [ 110 votes ]   [ Discuss This Article ]
By Source: Annals of Allergy • www.ProHealth.com • February 1, 1999


A nutritional supplement, NADH may be a valuable adjunctive therapy for CFS, according to a published report by a team of researchers at Georgetown University Medical Center in Washington, D.C. In a double-blind, placebo-controlled, cross-over study of 26 patients with CFS, Dr. Joseph Bellanti and colleagues reported that eight patients improved during the four weeks they were on NADH, while only two patients improved while on placebo. In a continuation of the study in which all the volunteers were knowingly taking the supplement, 72% (18 of 25 patients) reported significant improvement of their fatigue with no severe adverse effects from the supplement.

NADH (the reduced form of nicotinamide adenine dinucleotide) is a co-enzyme that triggers energy production in cells by generating ATP (adenosine triphosphate), which stores energy in cells. If cellular levels of NADH are depleted, brain and muscle cells lose their ability to function effectively. The theory is that as NADH levels rise in the body, the cells become more energized, making the body feel stronger and more energized.

This trial used a dosage of 10 mg per day (two tablets, taken 45 minutes before breakfast) of a patented, oral form of NADH manufactured under the brand name Enada by the European company Menuco.

This study was small, with just 26 patients, but it does appear to have been carefully controlled. The study protocol was approved by the Food and Drug Administration (FDA), which does not regulate the distribution of nutritional supplements but does regulate medical claims made for such products. This was the equivalent of a Phase II safety and efficacy trial.

Subjects were 17 women and nine men, ranging in age from 26 to 57, and they had experienced fatigue for an average of seven years (ranging from one to 16 years). One patient was African-American; 25 were Caucasian. All had fatigue, neurocognitive difficulties and sleep disturbances, and nearly all experienced postexertional malaise, headaches, muscle weakness, arthralgia, myalgias and a history of allergy. Eighteen had swollen or tender lymph nodes. There was no correlation between a specific symptom pattern or laboratory test results and response to treatment. Response was measured primarily by a subjective questionnaire, with at least a 10% improvement required to be considered a favorable response.

One of the subjects reported being overly stimulated, and the researchers suggested that patient’s dosage could have been decreased. Other non-responders may have benefited from an increased dosage. Dosages were not adjusted for weight in this study.

The study was published in the February 1999 issue of Annals of Allergy, Asthma and Immunology. A larger open-label study is planned at Georgetown. NADH also is being studied as a potential treatment for persons with Alzheimer’s disease and Parkinson’s disease.



Post a Comment

Featured Products From the ProHealth Store
Ultra EPA  - Fish Oil Vitamin D3 Extreme™ Mitochondria Ignite™ with NT Factor®

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
NAD+ Ignite with Niagen

Featured Products

Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium

Natural Remedies

Joint Aches May Have Met Their Match in Curcumin Joint Aches May Have Met Their Match in Curcumin
Restoring Gut Health: How to Create a Firewall Against Toxins Entering the Gut Wall Restoring Gut Health: How to Create a Firewall Against Toxins Entering the Gut Wall
Energy Breakthrough - One Fibromyalgia Patient’s Fortuitous Discovery Energy Breakthrough - One Fibromyalgia Patient’s Fortuitous Discovery
Cocoa's Polyphenol Riches - All the Health Benefits without the Sugar, Calories or Guilt Cocoa's Polyphenol Riches - All the Health Benefits without the Sugar, Calories or Guilt
Strengthen Cell Function with Energy-Boosting Niagen Strengthen Cell Function with Energy-Boosting Niagen

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map