Three powerhouse supplements have come together in a new way to support the liver and digestion and may just change the way we think about disease and pain.
The heart, lungs and brain get a lot of attention. After all, if one fails, the immediate impact is critical. Yet, each of these - and every other organ in the body - owes its long-term survival to the liver and its partner, your digestive tract.
And that's why Optimized Curcumin Liver unites three potent liver and digestive health supplements. They support the organs that support your health and may offer much larger health benefits.
Why a 3 in 1 Supplement?
The liver plays a vital role in digestion and nutrient storage as well as more than 300 metabolic functions. It also detoxifies the body, regulates hormones and is involved in the immune system. To say it's vital is an understatement. It is so important you can lose 75% of your liver and, given a chance, it will re-grow into a fully functioning, healthy liver. It's the only organ that can do that.
When the liver gets overwhelmed, health suffers. Symptoms of an exhausted liver can include chronic fatigue, moodiness and irritability, and skin irritations. Toxins, stress and hormone imbalances can wreak havoc on the liver's ability to perform all its functions. A 2015 study published in the Journal of Gastroenterology and Hepatology
reports that high estrogen and low testosterone levels in men indicates advanced liver damagei
Diet can also play a role, as today one in four Americans suffer from non-alcoholic fatty liver disease (NAFLD).ii
In the past, fatty liver was associated with excess alcohol consumption. Today it's associated with excess blood sugar. One of the liver's many jobs is to pull excess sugar from the blood and convert it into glycogen. As it stores more and more glycogen, liver cells become enlarged and inflamed, and if the swelling continues, they die.
Liver damage like this impacts digestion. Bile ducts in a damaged liver become blocked, reducing the ability to digest dietary fat. In addition, a damaged liver can't efficiently metabolize carbs, fats and proteins as part of digestion.
Inefficient digestion creates a host of problems in the intestines. Ultimately, whether it's small intestine bacterial overgrowth (SIBO), undigested food, or an immune response, the intestinal lining becomes inflamed. Some symptoms of this include bloating, gas, abdominal discomfort, and nausea.
Frequent occurrence of these symptoms indicates irritable bowel syndrome or disease (IBS/IBD). Left untreated, more serious conditions like leaky gut, Crohn's Disease, ulcers or worse can develop. Digestive problems like these have been linked to many chronic diseases, including fatigue, weakness, allergies, arthritis, poor memory, an inability to focus, and even cancer.
Just as bad, nutrient digestion suffers with the body lacking the vitamins, minerals and proteins needed to work right. Then, as the body lacks nutrients, toxins further build up and tax the liver even more.
The Connection Between Fibromyalgia, the Liver and Digestion
As if a digestive condition like IBS wasn't bad enough, research suggests links between bowel function and fibromyalgia. Studies report 60% of patients with conditions like Irritable Bowel Disease (or IBS) also experience fibromyalgiaiii
. An even earlier study reported 73% of fibromyalgia patients experienced altered bowel functioniv
. And in one study 33% of IBS patients met the criteria for fibromyalgia.v
More recently a study published in Digestive Diseases and Studies found significant links between symptoms of fibromyalgia and a more serious form of liver disease known as NASH or non-alcoholic steatohepatitis.vi
While it's not known if liver disease causes fibromyalgia, it is now known that a high percentage of fibromyalgia patients also suffer from liver disorders.
More research is needed, but the importance of the liver to every system in the body suggests keeping the liver healthy may be the key to overall health.
It's a complex system, but its needs are simple.
Here's What Makes Optimized Curcumin Liver Special
Optimized Curcumin Liver combines three of the most potent liver and digestive support nutrients. For thousands of years traditional medicines used artichoke, turmeric (the source of curcumin) and broccoli as digestive aids and to treat liver conditions. Modern science confirms these uses and has discovered they reduce inflammation and pain to support the liver and digestion.
. Where curcumin is well known for its ability to ease pain and reduce inflammation, Longvida Curcumin is a breakthrough supplement that elevates the power and potency through a proprietary process that makes it 65 times more bioavailable than regular curcumin. Normally, curcumin breaks down quickly during digestion, with the body only absorbing about 5% of the total amount ingested. Longvida Curcumin has been created to survive digestion to deliver a much higher dose.
Brassicare Broccoli Extract
. Broccoli contains sulforaphane, a compound known to support liver health with powerful antioxidant and anti-inflammatory properties. Brassicare contains glucoraphane, a precursor compound to sulforophane that delivers a high potency dose at lower concentrations than pure sulforophane. Research shows these compounds increase the liver's glutathione production, the body's most powerful antioxidant and toxin remover.vii
This protects against damage to the liver, intestines and all organs throughout the body. And according to recent research in animal trials, it may even help the liver reverse the damage of acute liver injury.viii
. Records dating back to 400 B.C. refer to artichoke as a medical remedy for indigestion and liver problems. Earlier studies support its use for indigestion, reporting reduced nausea, appetite loss, bloating, and constipation. In addition to its action as a digestive aid, artichoke extract improves liver enzymes that support liver function and digestion.
Who Gets the Biggest Benefits?
Each of these supplements could stand on their own as a powerful aid for the liver and digestion. Together, they create one incredible supplement to support the health of organs every person needs for long, healthy living with a great quality of life. Here are a few of Optimized Curcumin Liver's benefits:
. A healthy liver and intestinal tract digests foods and absorbs it easily. All of the nutrients in Optimized Curcumin Liver are known to support healthy digestion.
Alleviates Symptoms of IBS/IBD
. A recent study suggests highly bioavailable curcumin helps reduce intestinal inflammation and helps with symptoms of IBD.ix
Patients with IBS who have taken artichoke reported it alleviates symptoms and pain and improves the overall quality of life.x
Whole Body Antioxidant Protection
. Glucoraphane, found in broccoli extract, supports liver production of glutathione, the most powerful antioxidant in the body. Your liver uses it to remove toxins and neutralize free radicals from every organ, muscle and tissue in the body. The more you have, the less total damage you have. Curcumin is also recognized as a powerful antioxidant.xi
. A study performed by North Texas researchers found Longvida Curcumin extract helped reduce inflammation and encouraged faster physical healing. It specifically reduced the presence of IL-8, a protein that triggers an inflammatory response, and TNF-a, the protein that causes inflammation.xii
Reduces Liver Fat Accumulation
. As broccoli extract protects liver cells, curcumin appears to help the body reduce liver fat. A study reported curcumin improved liver fat content by nearly 80% with a positive effect on cholesterol and triglyceride levels.xiii
Protects Against Stress
. Cortisol, the stress hormone, puts stress on the liver. As the liver removes and breaks down hormones to keep them as balanced as possible, excess cortisol interferes with the liver doing its other jobs and interrupts normal digestion. By giving the liver the nutrients it needs to make it strong and efficient, it removes cortisol faster, keeps hormones balanced and helps to handle stress better.
How to Use Optimized Curcumin Liver:
Follow dosage directions on the label or consult with a doctor to determine your appropriate daily dosage.
Although the ingredients are known to be safe in much higher values than present in a single dose of Optimized Curcumin Liver, pregnant and nursing women should always consult with their doctors before starting a new supplement.
Anyone taking medications for liver disease or certain pain-relief medications should consult with their doctor to avoid interference with the effects of any prescribed medications.
Optimized Curcumin Liver delivers a breakthrough curcumin supplement with the addition of potent broccoli and artichoke extracts to create a powerhouse three-in-one supplement solution to ease indigestion, support vital liver function and promote great living and longevity.
* Copywriter and researcher Peter Rufa writes for a wide range of clients but specializes in health. He has written for doctors, supplement providers, healthcare, medical, and fitness organizations and businesses throughout the United States.
i) Marie Sinclair1,3,*, Mathis Grossmann2,3, Paul J Gow1,3 and Peter W Angus. Testosterone in men with advanced liver disease: Abnormalities and implications. Article first published online: 24 JAN 2015. DOI: 10.1111/jgh.12695. Journal of Gastroenterology and Hepatology Volume 30, Issue 2, pages 244–251, February 2015. http://onlinelibrary.wiley.com/doi/10.1111/jgh.12695/full
ii) Nonalcoholic Fatty Liver Disease: America’s Greatest Health Risk of 2015? Dr. Hyder Z. Jamal, MD, http://blogs.scientificamerican.com/guest-blog/2015/02/09/non-alcoholic-fatty-liver-disease-americas-greatest-health-risk-of-2015/
iii) Nonalcoholic Fatty Liver Disease: America’s Greatest Health Risk of 2015? Dr. Hyder Z. Jamal, MD, http://blogs.scientificamerican.com/guest-blog/2015/02/09/non-alcoholic-fatty-liver-disease-americas-greatest-health-risk-of-2015/
iv) Triadafilopoulos G1, Simms RW, Goldenberg DL. Bowel dysfunction in fibromyalgia syndrome. Dig Dis Sci. 1991 Jan;36(1):59-64. http://www.ncbi.nlm.nih.gov/pubmed/0001985007
v) Wallace DJ1, Hallegua DS. Fibromyalgia: the gastrointestinal link. Curr Pain Headache Rep. 2004 Oct;8(5):364-8. http://www.ncbi.nlm.nih.gov/pubmed/15361320
vi) Rogal SS1, Bielefeldt K, Wasan AD, Szigethy E, Lotrich F, DiMartini AF. Fibromyalgia symptoms and cirrhosis. Dig Dis Sci. 2015 May;60(5):1482-9. doi: 10.1007/s10620-014-3453-3. Epub 2014 Nov 30. http://www.ncbi.nlm.nih.gov/pubmed/25433921
vii) Kikuchi M1, Ushida Y1, Shiozawa H1, Umeda R1, Tsuruya K1, Aoki Y1, Suganuma H1, Nishizaki Y1. Sulforaphane-rich broccoli sprout extract improves hepatic abnormalities in male subjects. World J Gastroenterol. 2015 Nov 21;21(43):12457-67. doi: 10.3748/wjg.v21.i43.12457. http://www.ncbi.nlm.nih.gov/pubmed/26604653
vii) Yoshida K1, Ushida Y1, Ishijima T1, Suganuma H1, Inakuma T1, Yajima N1, Abe K1, Nakai Y1.Broccoli sprout extract induces detoxification-related gene expression and attenuates acute liver injury. World J Gastroenterol. 2015 Sep 21;21(35):10091-103. doi: 10.3748/wjg.v21.i35.10091. http://www.ncbi.nlm.nih.gov/pubmed/26401074
ix) Beloqui A1, Memvanga PB2, Coco R1, Reimondez-Troitiño S3, Alhouayek M4, Muccioli GG4, Alonso MJ5, Csaba N5, de la Fuente M6, Préat V7. A comparative study of curcumin-loaded lipid-based nanocarriers in the treatment of inflammatory bowel disease. Colloids Surf B Biointerfaces. 2016 Jul 1;143:327-35. doi: 10.1016/j.colsurfb.2016.03.038. Epub 2016 Mar 16. http://www.ncbi.nlm.nih.gov/pubmed/27022873
x) Bundy R1, Walker AF, Middleton RW, Marakis G, Booth JC. Artichoke leaf extract reduces symptoms of irritable bowel syndrome and improves quality of life in otherwise healthy volunteers suffering from concomitant dyspepsia: a subset analysis. J Altern Complement Med. 2004 Aug;10(4):667-9. http://www.ncbi.nlm.nih.gov/pubmed/15353023
xi) Zhong W1, Qian K2, Xiong J3, Ma K4, Wang A1, Zou Y5. Curcumin alleviates lipopolysaccharide induced sepsis and liver failure by suppression of oxidative stress-related inflammation via PI3K/AKT and NF-?B related signaling. Biomed Pharmacother. 2016 Jul 6;83:302-313. doi: 10.1016/j.biopha.2016.06.036. [Epub ahead of print] http://www.ncbi.nlm.nih.gov/pubmed/27393927
xii) McFarlin, Brian K., et al. Reduced inflammatory and muscle damage biomarkers following oral supplementation with bioavailable curcumin. BBA Clinical 5 (2016) 72–78. Available online 18 February 2016.
xiii) Rahmani S1, Asgary S2, Askari G1, Keshvari M2, Hatamipour M3, Feizi A4, Sahebkar A5,6. Treatment of Non-alcoholic Fatty Liver Disease with Curcumin: A Randomized Placebo-controlled Trial. Phytother Res. 2016 Jun 8. doi: 10.1002/ptr.5659. [Epub ahead of print] http://www.ncbi.nlm.nih.gov/pubmed/27270872