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Low Dose Naltrexone for Chronic Lyme Disease

  [ 11 votes ]   [ 1 Comment ]
By Jenna Seaver • • January 26, 2017

Low Dose Naltrexone for Chronic Lyme Disease
Reprinted from JennasLymeBlog with the kind permission of Jenna Seaver. To read the original article, click here.

Have you heard about LDN (Low Dose Naltrexone) for chronic Lyme disease? I am excited to say that I have been taking it successfully for chronic pain although it took awhile to kick in. There appear to be many amazing health benefits for taking LDN, including the inhibition of cancerous cell growth!
The major mechanism of action of LDN involves blocking the body’s opioid/narcotic receptors for just a very few hours (rather than the all-day blockade caused by the 50mg dosage). Those are the same receptors used by the body’s endorphins. The body responds to this by greatly increasing its endorphin production, and those higher levels last all day — far after the blockade by LDN has ended. Endorphins turn out to be the major normalizer/upregulator of one’s immune system.
It is best to start low at between .5 and 1.5 mg and work up to as much as 4.5 mg (vs 50 – 300 mg for drug addicts or alcoholics). My doctor prescribed 2 weeks at 1.5 mg, 2 weeks at 3 mg and three weeks ago I moved up to my full dose of 4.5 mg.  I didn’t notice any improvement during the first month (although I know a few people who felt benefits at 2 mg), but about two weeks into the full dose I started to notice a marked improvement in pain relief and general well-being.
I have read that some people who had NOT been diagnosed with Lyme and were treated with LDN for fibromyalgia had a worsening of symptoms due to an apparent immune response. This patient writes from LDN Yahoo group:
“LDN can and usually does backfire with untreated Lyme disease. That is how I discovered that I have Lyme, because I tried LDN and everything got much worse, and prompted me to get testing done that revealed Lyme. Since then I have heard the same story repeated again and again from many people with Lyme. In my opinion, the ability to tolerate LDN is a good test of the relative severity of infection when you do have Lyme. LDN seems to “turn the lights on” for your immune system and reveal everything that was previously invisible. If there’s nothing there, you’re fine. If your body is riddled with spirochetes, you’re in for a BUMPY ride as all-out warfare commences.  Lyme sufferers that have been on antibiotics for extended lengths of time or have less severe cases seem to do alright with LDN.”
Some people experience a relief in symptoms much faster than I did, but like most treatments it takes consistency for lasting relief.
Some of the other things LDN has found to be helpful in treating:
ALS (Lou Gehrig’s disease)
Alzheimer’s disease
Ankylosing spondylitis
Autism (see Jacob’s amazing piano-playing story in the MOVIE)
Behcet’s Disease
Celiac disease
Chronic fatigue syndrome
CREST syndrome
Crohn’s disease
Hashimoto’s Thyroiditis
Inflammatory bowel disease (IBS)
Multiple sclerosis (MS)
Myasthenia Gravis (MG)
Nephrotic Syndrome
Parkinson’s disease
Primary lateral sclerosis (PLS)
Primary Biliary Cirrhosis
Progressive Supranuclear Palsy
Rheumatoid arthritis
Sjogren’s Syndrome
Stiff Person Syndrome (SPS)
Systemic Lupus (SLE)
Transverse Myelitis
Ulcerative colitis
Wegener’s Granulomatosis
Additionally, LDN has been found helpful in combating the following cancers:
Brain tumors (both astrocytoma and glioblastoma)
Bladder Cancer
Breast cancer
Colon & Rectal Cancer
Endometrial cancer
Head and neck squamous cell carcinoma
Liver Cancer
Lung Cancer (both small cell and non-mmall cell)
Lymphocytic Leukemia (chronic)
Lymphoma (Hodgkin’s and Non-Hodgkin’s)
Malignant Melanoma
Multiple Myeloma
Myeloid leukemia
Ovarian Cancer
Pancreatic Cancer
Prostate Cancer (untreated)
Renal Cell Carcinoma
Throat Cancer
Uterine Cancer
Where do you get it?
Like all prescription medications LDN must be prescribed by a MD, and it is usually mixed by an independent lab and sent directly to you rather than through a pharmacy.  No, it is not covered by insurance but thankfully it is relatively inexpensive – between $30 and $40 per month.
For more information:
LDN – The Movie
The LDN Book by Linda Elsegood
video testimonials
the mechanics of LDN
Research: is written by Jenna Seaver, a writer who is a victim of Lyme disease herself. Formerly a successful entrepreneur, competitive equestrian, wife, mother to six and grandmother to seven, Jenna is now single having lost most of family, friends and unfortunately all her horses, dogs and cats as a result of this disease. Finally recovering (however slowly) after dozens of failed protocols Jenna now focuses on writing, Lyme activism and internet marketing.

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Article Comments Post a Comment

Posted by:
Jul 13, 2017
Hi Jenna,

I am taking LDN for Fibromyalgia, I also have Epstein Barr Virus which is what I think created the Fibro. It is having but I have been having that bumpy ride you are talking about. I am now on 1 mg after at least six months of treatment and I have a mysterious rash on my neck and face. What did you do to treat you Lymes so you could continue on with your LDN treatment. I was tested for Lyme's about a year ago but it was negative. I have heard that can happen even if you have Lyme's or maybe I wan't tested for the the type of Lyme's I have. I would like to hear how you are healing yourself. Thank you so much,
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