ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Basic Aromatherapy to Help Balance and Calm

Tea drinkers have lower glaucoma risk

Soy, cruciferous vegetables could help lower breast cancer treatment side effects

The Long-Term Benefits of Drinking Oolong Tea

Why You Should Try This Sweet-Smelling and Health-Boosting Essential Oil

Wonderful White Tea: A Drink Fit for an Emperor

Arnica: This Powerful Herb Promotes Various Kinds of Healing

Chamomile Tea: Why This Ancient Therapeutic Drink Still Stands Out Today

Get ‘Hooked’ on Cat’s Claw: The Many Benefits of This Amazonian Herb

Try Apple Cider Vinegar and Black Cumin Oil as Your Go-To Salad Dressing

 
Print Page
Email Article

Broccoli compound could be helpful to diabetes

  [ Not Yet Rated ]   [ Discuss This Article ]
By Life Extension • www.ProHealth.com • June 21, 2017


Reprinted with the kind permission of Life Extension.

June 19 2017. The June 14, 2017 issue of Science Translational Medicine published the finding of an ability for sulforaphane, a compound that occurs in broccoli and other vegetables, to lower the liver’s production of glucose.

By comparing gene signatures for diabetes with the potential ability of 3,852 compounds to affect these genes, Anders Rosengren and colleagues identified sulforaphane as having the highest overlap. “A large number of genetic variants and tissue gene expression profiles (“disease signatures”) have been associated with complex polygenic diseases over the last decade,” the authors explain. “One potentially interesting approach is to use genetic and gene expression data to interrogate libraries of drug signatures. A drug signature denotes differentially expressed genes between untreated and treated samples and takes into account that most compounds have multiple gene effects on expression beyond the primary target.”

In rat liver cells, the administration of sulforaphane was associated with a decrease of glucose production. In rodents with dietary-induced diabetes, sulforaphane decreased excess glucose production and glucose intolerance to a degree comparable to that of metformin. "We tested removing sulforaphane from the extract and the effect disappeared,” Dr Rosengren reported. “We also looked at the genes from the liver of the animals and saw that the 50 key genes had been changed in the right direction."

When tested in a trial of diabetics, broccoli sprout extract significantly improved fasting glucose levels in obese participants who entered the study with dysregulated disease compared to controls.

"There are strong indications that this can become a valuable supplement to existing medication," Dr Rosengren predicted. "Sulforaphane targets a central mechanism in type 2 diabetes and has a mild side-effect profile. As functional food, it can reach the patients faster than a medication, and it is also an interesting concept from a diabetes perspective where diet is central."



Post a Comment

Featured Products From the ProHealth Store
Vitamin D3 Extreme™ FibroSleep™ Optimized Curcumin Longvida®


Article Comments



Be the first to comment on this article!

Post a Comment


 
Optimized Curcumin Longvida with Omega-3

Featured Products

Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid

Natural Remedies

Magnesium + Malic Acid: One-Two Punch for Pain & Fatigue Magnesium + Malic Acid: One-Two Punch for Pain & Fatigue
Physically and Mentally Exhausted? How to Restore Energy at Its Source Physically and Mentally Exhausted? How to Restore Energy at Its Source
Itching to Find Dry Skin Relief? Itching to Find Dry Skin Relief?
A Hard-Working Molecule that May Help Ease Pain & Brighten Mood A Hard-Working Molecule that May Help Ease Pain & Brighten Mood
Coenzyme Q10 - The Energy Maker Coenzyme Q10 - The Energy Maker

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2018 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map