ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Is Magnesium the Missing Link in Your Heart Healthy Routine?

Why the Mediterranean Diet Is so Successful

A Little Zinc Goes a Long Way

Supplementation with vitamin D associated with improved testosterone, erectile function among middle...

Vitamin D deficiency increases risk of chronic headache

Wearable biosensors can flag illness, Lyme disease, risk for diabetes; low airplane oxygen

VIDEO: The Best Brain Foods That Help Increase Your Memory!

More evidence for calorie restriction’s longevity effect

Iron (And More) For Lasting, Natural Energy

Affordable Care Act made cancer screening more accessible for millions, study finds

 
Print Page
Email Article

Rush Testing Kinder, Gentler Therapy for Lung Cancer

  [ 173 votes ]   [ Discuss This Article ]
www.ProHealth.com • May 22, 2003


CHICAGO -- Oncologists at Rush-Presbyterian-St. Luke's Medical Center have begun testing a new medication that seeks to improve lung cancer treatment, reduce chemotherapy's common side effects and decrease infusion time from one hour to about 15 minutes.

The medication being studied is called Xyotax, which links paclitaxel, a commonly used chemotherapuetic agent, to a biogradeable polymer. This polymer creates a new chemical, designed to deliver higher and potentially more effective levels of paclitaxel to tumors.

Paclitaxel is one of the families of chemotherapy agents known as taxanes, the most widely used anticancer drugs in the treatment of non-small cell lung, breast, ovarian, and prostate cancers. Patients with non-small cell lung cancer who qualify for this Phase III study will receive either Xyotax, or another therapy called docetaxel.

"It is a kinder, gentler treatment for lung cancer," said Dr. Philip Bonomi, director of the Rush section of Oncology and Hematology and the only Chicago investigator in this study. "Xyotax offers patients convenience, shorter time spent in doctors' offices, and I believe it will be less toxic."

Unlike blood vessels in healthy tissue, those in tumor tissues have openings that make them porous to large molecules. Xyotax flows through healthy blood vessels and because the chemotherapy is inactive when bound to the polymer, lower levels of the drug are seen in the bloodstream. However, in tumor blood vessels, Xyotax leaks through the pores and is trapped in tumor tissue.

Xyotax is taken up by tumor cells through a process called pinocytosis. Because the polymer is made up of biodigestible amino acids, it is metabolized inside the tumor, releasing the paclitexal.

This allows Xyotax to bypass a primary mechanism by which tumor cells grow resistant. The result is that Xyotax should work better and be potentially safer than many existing chemotherapy agents.

Bonomi said that because this is a Phase III study, it is unclear just how well patients who take Xyotax will do. Bonomi believes that even if this drug shows a small improvement, the decreased side effects -- nausea, hair loss and fatigue -- it still might make Xyotax an attractive alternative to other chemotherapy agents if it gets Food and Drug Administration approval for widespread use.

Lung cancer is the leading cancer killer in both men and women. There were an estimated 156,900 deaths from lung cancer in the United States in 2000 and non small cell lung cancer deaths account for 85 percent of the 164,000 news cases of lung cancer that develop each year.



Post a Comment

Featured Products From the ProHealth Store
FibroSleep™ Ultra ATP+, Double Strength Energy NADH™ 12.5mg

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
NAD+ Ignite with Niagen

Featured Products

Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium

Natural Remedies

The Most Powerful Natural Antioxidant Discovered to Date - Hydroxytyrosol The Most Powerful Natural Antioxidant Discovered to Date - Hydroxytyrosol
Herbal Inflammation Management for Whole Body Health Herbal Inflammation Management for Whole Body Health
Stop Bacteria With Nature's Antibiotics Stop Bacteria With Nature's Antibiotics
Mitochondria-Booster NIAGEN® Shows Promise in First Human Clinical Trial Mitochondria-Booster NIAGEN® Shows Promise in First Human Clinical Trial
Guarding Against the Dangers of Vitamin D Deficiency Guarding Against the Dangers of Vitamin D Deficiency

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map