ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

SURVEY: Cognitive Impairment II

Top 3 Nutrients to Detox the Liver and Soothe Digestion

Natural Bladder Control, Go Less and Live More

Top Vitamin and Mineral Deficiencies — Are You at Risk?

Vital Molecule Increases Cellular Energy and Improves Cognitive Function

Omega Fix for Obesity: How the Right Fats Fight Fat

How Pomegranate May Protect Against Cancer

Trimming the spare tire: Canola oil may cut belly fat

The Onion: Cancer Fighter and Food Preserver

Safely Reduce a Common Cause of Stomach Distress

 
Print Page
Email Article

Rush Testing Kinder, Gentler Therapy for Lung Cancer

  [ 173 votes ]   [ Discuss This Article ]
www.ProHealth.com • May 22, 2003


CHICAGO -- Oncologists at Rush-Presbyterian-St. Luke's Medical Center have begun testing a new medication that seeks to improve lung cancer treatment, reduce chemotherapy's common side effects and decrease infusion time from one hour to about 15 minutes.

The medication being studied is called Xyotax, which links paclitaxel, a commonly used chemotherapuetic agent, to a biogradeable polymer. This polymer creates a new chemical, designed to deliver higher and potentially more effective levels of paclitaxel to tumors.

Paclitaxel is one of the families of chemotherapy agents known as taxanes, the most widely used anticancer drugs in the treatment of non-small cell lung, breast, ovarian, and prostate cancers. Patients with non-small cell lung cancer who qualify for this Phase III study will receive either Xyotax, or another therapy called docetaxel.

"It is a kinder, gentler treatment for lung cancer," said Dr. Philip Bonomi, director of the Rush section of Oncology and Hematology and the only Chicago investigator in this study. "Xyotax offers patients convenience, shorter time spent in doctors' offices, and I believe it will be less toxic."

Unlike blood vessels in healthy tissue, those in tumor tissues have openings that make them porous to large molecules. Xyotax flows through healthy blood vessels and because the chemotherapy is inactive when bound to the polymer, lower levels of the drug are seen in the bloodstream. However, in tumor blood vessels, Xyotax leaks through the pores and is trapped in tumor tissue.

Xyotax is taken up by tumor cells through a process called pinocytosis. Because the polymer is made up of biodigestible amino acids, it is metabolized inside the tumor, releasing the paclitexal.

This allows Xyotax to bypass a primary mechanism by which tumor cells grow resistant. The result is that Xyotax should work better and be potentially safer than many existing chemotherapy agents.

Bonomi said that because this is a Phase III study, it is unclear just how well patients who take Xyotax will do. Bonomi believes that even if this drug shows a small improvement, the decreased side effects -- nausea, hair loss and fatigue -- it still might make Xyotax an attractive alternative to other chemotherapy agents if it gets Food and Drug Administration approval for widespread use.

Lung cancer is the leading cancer killer in both men and women. There were an estimated 156,900 deaths from lung cancer in the United States in 2000 and non small cell lung cancer deaths account for 85 percent of the 164,000 news cases of lung cancer that develop each year.



Post a Comment

Featured Products From the ProHealth Store
Energy NADH™ 12.5mg FibroSleep™ Optimized Curcumin Longvida®


Article Comments



Be the first to comment on this article!

Post a Comment


 
Natural Pain Relief Supplements

Featured Products

Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid

Natural Remedies

Cocoa's Polyphenol Riches - All the Health Benefits without the Sugar, Calories or Guilt Cocoa's Polyphenol Riches - All the Health Benefits without the Sugar, Calories or Guilt
How to Jump-start and Sustain Energy Production in CFS How to Jump-start and Sustain Energy Production in CFS
The Big Blue Fish that Helps Chase the Blues Away The Big Blue Fish that Helps Chase the Blues Away
Bone Broth Benefits for Digestion, Arthritis and Cellulite Bone Broth Benefits for Digestion, Arthritis and Cellulite
Sunshine Vitamin Has D-lightful Health Benefits Sunshine Vitamin Has D-lightful Health Benefits

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map